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Database: UniProt
Entry: A0A1D5R5F4_MACMU
LinkDB: A0A1D5R5F4_MACMU
Original site: A0A1D5R5F4_MACMU 
ID   A0A1D5R5F4_MACMU        Unreviewed;       999 AA.
AC   A0A1D5R5F4;
DT   30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2016, sequence version 1.
DT   05-DEC-2018, entry version 13.
DE   SubName: Full=Inositol 1,4,5-trisphosphate receptor type 1 {ECO:0000313|Ensembl:ENSMMUP00000055541};
GN   Name=ITPR1 {ECO:0000313|Ensembl:ENSMMUP00000055541};
OS   Macaca mulatta (Rhesus macaque).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9544 {ECO:0000313|Ensembl:ENSMMUP00000055541, ECO:0000313|Proteomes:UP000006718};
RN   [1] {ECO:0000313|Ensembl:ENSMMUP00000055541, ECO:0000313|Proteomes:UP000006718}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=17573 {ECO:0000313|Ensembl:ENSMMUP00000055541,
RC   ECO:0000313|Proteomes:UP000006718};
RX   PubMed=17431167; DOI=10.1126/science.1139247;
RA   Gibbs R.A., Rogers J., Katze M.G., Bumgarner R., Weinstock G.M.,
RA   Mardis E.R., Remington K.A., Strausberg R.L., Venter J.C.,
RA   Wilson R.K., Batzer M.A., Bustamante C.D., Eichler E.E., Hahn M.W.,
RA   Hardison R.C., Makova K.D., Miller W., Milosavljevic A., Palermo R.E.,
RA   Siepel A., Sikela J.M., Attaway T., Bell S., Bernard K.E., Buhay C.J.,
RA   Chandrabose M.N., Dao M., Davis C., Delehaunty K.D., Ding Y.,
RA   Dinh H.H., Dugan-Rocha S., Fulton L.A., Gabisi R.A., Garner T.T.,
RA   Godfrey J., Hawes A.C., Hernandez J., Hines S., Holder M., Hume J.,
RA   Jhangiani S.N., Joshi V., Khan Z.M., Kirkness E.F., Cree A.,
RA   Fowler R.G., Lee S., Lewis L.R., Li Z., Liu Y.-S., Moore S.M.,
RA   Muzny D., Nazareth L.V., Ngo D.N., Okwuonu G.O., Pai G., Parker D.,
RA   Paul H.A., Pfannkoch C., Pohl C.S., Rogers Y.-H.C., Ruiz S.J.,
RA   Sabo A., Santibanez J., Schneider B.W., Smith S.M., Sodergren E.,
RA   Svatek A.F., Utterback T.R., Vattathil S., Warren W., White C.S.,
RA   Chinwalla A.T., Feng Y., Halpern A.L., Hillier L.W., Huang X.,
RA   Minx P., Nelson J.O., Pepin K.H., Qin X., Sutton G.G., Venter E.,
RA   Walenz B.P., Wallis J.W., Worley K.C., Yang S.-P., Jones S.M.,
RA   Marra M.A., Rocchi M., Schein J.E., Baertsch R., Clarke L., Csuros M.,
RA   Glasscock J., Harris R.A., Havlak P., Jackson A.R., Jiang H., Liu Y.,
RA   Messina D.N., Shen Y., Song H.X.-Z., Wylie T., Zhang L., Birney E.,
RA   Han K., Konkel M.K., Lee J., Smit A.F.A., Ullmer B., Wang H., Xing J.,
RA   Burhans R., Cheng Z., Karro J.E., Ma J., Raney B., She X., Cox M.J.,
RA   Demuth J.P., Dumas L.J., Han S.-G., Hopkins J., Karimpour-Fard A.,
RA   Kim Y.H., Pollack J.R., Vinar T., Addo-Quaye C., Degenhardt J.,
RA   Denby A., Hubisz M.J., Indap A., Kosiol C., Lahn B.T., Lawson H.A.,
RA   Marklein A., Nielsen R., Vallender E.J., Clark A.G., Ferguson B.,
RA   Hernandez R.D., Hirani K., Kehrer-Sawatzki H., Kolb J., Patil S.,
RA   Pu L.-L., Ren Y., Smith D.G., Wheeler D.A., Schenck I., Ball E.V.,
RA   Chen R., Cooper D.N., Giardine B., Hsu F., Kent W.J., Lesk A.,
RA   Nelson D.L., O'brien W.E., Pruefer K., Stenson P.D., Wallace J.C.,
RA   Ke H., Liu X.-M., Wang P., Xiang A.P., Yang F., Barber G.P.,
RA   Haussler D., Karolchik D., Kern A.D., Kuhn R.M., Smith K.E.,
RA   Zwieg A.S.;
RT   "Evolutionary and biomedical insights from the rhesus macaque
RT   genome.";
RL   Science 316:222-234(2007).
RN   [2] {ECO:0000313|Ensembl:ENSMMUP00000055541}
RP   IDENTIFICATION.
RC   STRAIN=17573 {ECO:0000313|Ensembl:ENSMMUP00000055541};
RG   Ensembl;
RL   Submitted (OCT-2016) to UniProtKB.
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DR   EMBL; JSUE03023307; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; JSUE03023308; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; JSUE03023309; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Ensembl; ENSMMUT00000054295; ENSMMUP00000055541; ENSMMUG00000012574.
DR   GeneTree; ENSGT00940000155071; -.
DR   Proteomes; UP000006718; Chromosome 2.
DR   ExpressionAtlas; A0A1D5R5F4; baseline.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:InterPro.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0070679; F:inositol 1,4,5 trisphosphate binding; IEA:InterPro.
DR   GO; GO:0005220; F:inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; IEA:InterPro.
DR   InterPro; IPR014821; Ins145_P3_rcpt.
DR   InterPro; IPR000493; InsP3_rcpt.
DR   InterPro; IPR036300; MIR_dom_sf.
DR   InterPro; IPR016093; MIR_motif.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   InterPro; IPR035910; RyR/IP3R_RIH_dom_sf.
DR   PANTHER; PTHR13715; PTHR13715; 1.
DR   Pfam; PF08709; Ins145_P3_rec; 1.
DR   Pfam; PF02815; MIR; 1.
DR   Pfam; PF01365; RYDR_ITPR; 1.
DR   PRINTS; PR00779; INSP3RECEPTR.
DR   SMART; SM00472; MIR; 4.
DR   SUPFAM; SSF100909; SSF100909; 1.
DR   SUPFAM; SSF82109; SSF82109; 2.
DR   PROSITE; PS50919; MIR; 5.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000006718};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006718};
KW   Repeat {ECO:0000256|SAAS:SAAS00903904}.
FT   DOMAIN       58    112       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      119    169       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      177    233       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      240    319       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      325    381       MIR. {ECO:0000259|PROSITE:PS50919}.
SQ   SEQUENCE   999 AA;  113958 MW;  DFF93FB56A1985A8 CRC64;
     DCLFKLCPMN RYSAQKQFWK AAKPGANSTT DAVLLNKLHH AADLEKKQNE TENRKLLGTV
     IQYGNVIQLL HLKSNKYLTV NKRLPALLEK NAMRVTLDEA GNEGSWFYIQ PFYKLRSIGD
     SVVIGDKVVL NPVNAGQPLH ASSHQLVDNP GCNEVNSVNC NTSWKIVLFM KWSDNKDDIL
     KGGDVVRLFH AEQEKFLTCD EHRKKQHVFL RTTGRQSATS ATSSKALWEV EVVQHDPCRG
     GAGYWNSLFR FKHLATGHYL AAEVDPDFEE ECLEFQPSVD PDQDASRSRL RNAQEKMVYS
     LVSVPEGNDI SSIFELDPTT LRGGDSLVPR NSYVRLRHLC TNTWVHSTNI PIDKEEEKPV
     MLKIGTSPVK EDKEAFAIVP VSPAEVRDLD FANDASKVLG SIAGKLEKGT ITQNERRSVT
     KLLEDLVYFV TGGTNSGQDV LEVVFSKPNR ERQKLMREQN ILKQIFKLLQ APFTDCGDGP
     MLRLEELGDQ RHAPFRHICR LCYRVLRHSQ QDYRKNQEYI AKQFGFMQKQ IGYDVLAEDT
     ITALLHNNRK LLEKHITAAE IDTFVSLVRK NREPRFLDYL SDLCVSMNKS IPVTQELICK
     AVLNPTNADI LIETKLVLSR FEFEGVSSTG ENALEAGEDE EEVWLFWRDS NKEIRSKSVR
     ELAQDAKEGQ KEDRDVLSYY RYQLNLFARM CLDRQYLAIN EISGQLDVDL ILRCMSDENL
     PYDLRASFCR LMLHMHVDRD PQEQVTPVKY ARLWSEIPSE IAIDDYDSSG ASKDEIKERF
     AQTMEFVEEY LRDVVCQRFP FSDKEKNKLT FEVVNLARNL IYFGFYNFSD LLRLTKILLA
     ILDCVHVTTI FPISKMAKGE ENKGSNVMRS IHGVGELMTQ VVLRGGGFLP MTPMAAAPEG
     NVKQAEPEKE DIMVMDTKLK IIEILQFILN VRLDYRISCL LCIFKREFDE SNSQTSETSS
     GNISQEGPSN VPGALDFEHI EEQAEGIFGG RKVYFQLLW
//
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