ID A0A1D5R885_MACMU Unreviewed; 1225 AA.
AC A0A1D5R885;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=NHS like 2 {ECO:0000313|Ensembl:ENSMMUP00000056525.1};
GN Name=NHSL2 {ECO:0000313|Ensembl:ENSMMUP00000056525.1};
OS Macaca mulatta (Rhesus macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9544 {ECO:0000313|Ensembl:ENSMMUP00000056525.1, ECO:0000313|Proteomes:UP000006718};
RN [1] {ECO:0000313|Proteomes:UP000006718}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=17573 {ECO:0000313|Proteomes:UP000006718};
RX PubMed=17431167; DOI=10.1126/science.1139247;
RA Gibbs R.A., Rogers J., Katze M.G., Bumgarner R., Weinstock G.M.,
RA Mardis E.R., Remington K.A., Strausberg R.L., Venter J.C., Wilson R.K.,
RA Batzer M.A., Bustamante C.D., Eichler E.E., Hahn M.W., Hardison R.C.,
RA Makova K.D., Miller W., Milosavljevic A., Palermo R.E., Siepel A.,
RA Sikela J.M., Attaway T., Bell S., Bernard K.E., Buhay C.J.,
RA Chandrabose M.N., Dao M., Davis C., Delehaunty K.D., Ding Y., Dinh H.H.,
RA Dugan-Rocha S., Fulton L.A., Gabisi R.A., Garner T.T., Godfrey J.,
RA Hawes A.C., Hernandez J., Hines S., Holder M., Hume J., Jhangiani S.N.,
RA Joshi V., Khan Z.M., Kirkness E.F., Cree A., Fowler R.G., Lee S.,
RA Lewis L.R., Li Z., Liu Y.-S., Moore S.M., Muzny D., Nazareth L.V.,
RA Ngo D.N., Okwuonu G.O., Pai G., Parker D., Paul H.A., Pfannkoch C.,
RA Pohl C.S., Rogers Y.-H.C., Ruiz S.J., Sabo A., Santibanez J.,
RA Schneider B.W., Smith S.M., Sodergren E., Svatek A.F., Utterback T.R.,
RA Vattathil S., Warren W., White C.S., Chinwalla A.T., Feng Y., Halpern A.L.,
RA Hillier L.W., Huang X., Minx P., Nelson J.O., Pepin K.H., Qin X.,
RA Sutton G.G., Venter E., Walenz B.P., Wallis J.W., Worley K.C., Yang S.-P.,
RA Jones S.M., Marra M.A., Rocchi M., Schein J.E., Baertsch R., Clarke L.,
RA Csuros M., Glasscock J., Harris R.A., Havlak P., Jackson A.R., Jiang H.,
RA Liu Y., Messina D.N., Shen Y., Song H.X.-Z., Wylie T., Zhang L., Birney E.,
RA Han K., Konkel M.K., Lee J., Smit A.F.A., Ullmer B., Wang H., Xing J.,
RA Burhans R., Cheng Z., Karro J.E., Ma J., Raney B., She X., Cox M.J.,
RA Demuth J.P., Dumas L.J., Han S.-G., Hopkins J., Karimpour-Fard A.,
RA Kim Y.H., Pollack J.R., Vinar T., Addo-Quaye C., Degenhardt J., Denby A.,
RA Hubisz M.J., Indap A., Kosiol C., Lahn B.T., Lawson H.A., Marklein A.,
RA Nielsen R., Vallender E.J., Clark A.G., Ferguson B., Hernandez R.D.,
RA Hirani K., Kehrer-Sawatzki H., Kolb J., Patil S., Pu L.-L., Ren Y.,
RA Smith D.G., Wheeler D.A., Schenck I., Ball E.V., Chen R., Cooper D.N.,
RA Giardine B., Hsu F., Kent W.J., Lesk A., Nelson D.L., O'brien W.E.,
RA Pruefer K., Stenson P.D., Wallace J.C., Ke H., Liu X.-M., Wang P.,
RA Xiang A.P., Yang F., Barber G.P., Haussler D., Karolchik D., Kern A.D.,
RA Kuhn R.M., Smith K.E., Zwieg A.S.;
RT "Evolutionary and biomedical insights from the rhesus macaque genome.";
RL Science 316:222-234(2007).
RN [2] {ECO:0000313|Ensembl:ENSMMUP00000056525.1}
RP IDENTIFICATION.
RC STRAIN=17573 {ECO:0000313|Ensembl:ENSMMUP00000056525.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; A0A1D5R885; -.
DR STRING; 9544.ENSMMUP00000056525; -.
DR Ensembl; ENSMMUT00000074066.2; ENSMMUP00000056525.1; ENSMMUG00000021924.3.
DR VEuPathDB; HostDB:ENSMMUG00000021924; -.
DR GeneTree; ENSGT00950000182963; -.
DR InParanoid; A0A1D5R885; -.
DR OMA; EPEDPHQ; -.
DR Proteomes; UP000006718; Chromosome X.
DR ExpressionAtlas; A0A1D5R885; baseline.
DR GO; GO:0030154; P:cell differentiation; IBA:GO_Central.
DR Gene3D; 1.20.5.340; -; 1.
DR InterPro; IPR024845; NHS-like.
DR PANTHER; PTHR23039; NANCE-HORAN SYNDROME PROTEIN; 1.
DR PANTHER; PTHR23039:SF2; NHS-LIKE PROTEIN 2; 1.
DR Pfam; PF15273; NHS; 3.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000006718}.
FT REGION 161..181
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 193..215
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 290..316
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 335..370
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 472..510
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 543..633
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 670..766
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 812..1010
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1041..1093
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1128..1203
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 161..176
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 670..695
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 706..736
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 812..832
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 852..873
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 874..888
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 934..970
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1050..1071
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1140..1169
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1225 AA; 133057 MW; DB30169AB8544185 CRC64;
MPFYRRTVVP QRLCPRNPPQ QLAELSDVSH LAALSLLRQL ADLCGHSLAL LEDLEGHLLA
LGRRTDSLYR RTVRLRRRLP CRLLGPEEDE EELAAANSGR ENATATAHSR SSWRQPVNVF
LSSGRPPSVE ELLREAQLNL QSLLQEEYEE QYSEARLVGQ TFRSSDEATK PTPNPRPQSA
RRLEFVLMPT KRQLSEDETT TQGVRAPEAS LSLSTTADKQ TAWNNLFPLP ILEEKRWPQP
CSTQSDIVPI NISGQQFDKH ASLRHSLFNT ETAVNPKSTL RRRRTIIGFS NFSQRDQGHS
NSPAGSVAHS TTSDIRPSHS ILEGVHGRVA VGQDARFPSL TSPGLRTPSS EPDEPHQARS
GPNPPGMESM GMVYSVPSSC NGPTESTFST SWKGDAFTYM TPSATSQSNQ VNENGKNPSC
GNSWVSLDKV PPLVPKEAAT LLVARDNPAG CSGSAGYPEH LIQRRHMPER PSKIGLLTSG
TTRLETGPGG ASRFRERSLS VPTDSGTTDV DYDEEQKANE ACALPFASTS SEGSNSADNI
ASLSAQQEAQ HRRQRSKSIS LRKAKKKPSP PTRSVSLVKD EPGLLPEGGS ALPKDQRPKS
LCLSLEHQGH HSSHPDAQGH PAVPNHKDPE GTQFSHHWYL TDWKSGDTYQ SLSSSSTATG
TTVIECTQVQ GSSESLASPS TSRATTPSQL SIEVEAREIS SPGRPPGLMS PSSGYSSQSE
TPTPTVSMSL TLGHLPPPSS SVRVRPVVPE RKSSLPPTSP MEKFPKSRLS FDLPLTSSPN
LDLSGMSISI RSKTKVSRHH SETNFGVKLA QKTNPNQPIM PMVTQSDLRS VRLRSVSKSE
PEDDIESPDC AEESRAEEVF TLPERKTKPP VAEKPPVARR PPSLVHKPPS VPEEYALTSP
TLAMPPRSSI QHARPLPQDS YTVVRKPKSS SFPDGRSPGE STAPSSLVFT PFASSSGAFF
SGTQQPPQGS VEDEGPKVRA LPERISLQSQ EEAEKKKGKI PPPVPKKPSV LYLPLTSPTA
QMEAYVAEPR LPLSPIITLE EDAKCPPTSD DLQSLGQRVT STPQADSERE ASPLGSSVEP
GTEEKSLISD KTAEWIAEDD DDVFVASRTT EDLFTVIHRS KRKLLGWKEP GEAFVGGRTS
SHSPIKNTAE SPISESTATT GSGSSANLDA GRNDDFKALL QKKGSKATPR SRPSAAELLK
TTNPLARRII AQFSKDYETT DNPST
//
