ID A0A1D5URX0_WHEAT Unreviewed; 1109 AA.
AC A0A1D5URX0;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN ORFNames=CAMPLR22A2D_LOCUS5793 {ECO:0000313|EMBL:SPT21158.1},
GN CFC21_033077 {ECO:0000313|EMBL:KAF7019949.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS2D02G590600.1};
RN [1] {ECO:0000313|EMBL:KAF7019949.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7019949.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS2D02G590600.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS2D02G590600.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EMBL:SPT21158.1, ECO:0000313|Proteomes:UP000280104}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Thind KAUR A.;
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EnsemblPlants:TraesCS2D02G590600.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [5] {ECO:0000313|EMBL:KAF7019949.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7019949.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the protein kinase superfamily. Ser/Thr protein
CC kinase family. {ECO:0000256|ARBA:ARBA00008684}.
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DR EMBL; CM022216; KAF7019949.1; -; Genomic_DNA.
DR EMBL; LS480641; SPT21158.1; -; Genomic_DNA.
DR SMR; A0A1D5URX0; -.
DR STRING; 4565.A0A1D5URX0; -.
DR EnsemblPlants; TraesCS2D02G590600.1; TraesCS2D02G590600.1; TraesCS2D02G590600.
DR Gramene; TraesCAD_scaffold_004424_01G000100.1; TraesCAD_scaffold_004424_01G000100.1; TraesCAD_scaffold_004424_01G000100.
DR Gramene; TraesCLE_scaffold_011361_01G000600.1; TraesCLE_scaffold_011361_01G000600.1; TraesCLE_scaffold_011361_01G000600.
DR Gramene; TraesCS2D02G590600.1; TraesCS2D02G590600.1; TraesCS2D02G590600.
DR Gramene; TraesCS2D03G1287500.1; TraesCS2D03G1287500.1.CDS; TraesCS2D03G1287500.
DR Gramene; TraesKAR2D01G0468290.1; cds.TraesKAR2D01G0468290.1; TraesKAR2D01G0468290.
DR Gramene; TraesPAR_scaffold_008977_01G000300.1; TraesPAR_scaffold_008977_01G000300.1; TraesPAR_scaffold_008977_01G000300.
DR Gramene; TraesROB_scaffold_010744_01G000700.1; TraesROB_scaffold_010744_01G000700.1; TraesROB_scaffold_010744_01G000700.
DR OMA; LEWFDIG; -.
DR Proteomes; UP000019116; Chromosome 2D.
DR Proteomes; UP000280104; Chromosome ii.
DR Proteomes; UP000815260; Chromosome 2D.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 4.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR013210; LRR_N_plant-typ.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR27008; OS04G0122200 PROTEIN; 1.
DR PANTHER; PTHR27008:SF413; PROTEIN KINASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00560; LRR_1; 3.
DR Pfam; PF13855; LRR_8; 6.
DR Pfam; PF08263; LRRNT_2; 1.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00369; LRR_TYP; 10.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF52047; RNI-like; 2.
DR PROSITE; PS51450; LRR; 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..1109
FT /note="non-specific serine/threonine protein kinase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5039972578"
FT TRANSMEM 741..761
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 798..1092
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT BINDING 826
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 1109 AA; 120588 MW; 66A95E330AE327AA CRC64;
MAMAFPLMIL TLIFLQPAPV LAAPSLPSNN GTDLAALLEF KAQLSDPIGI LGQNWTTATS
FCHWVGVSCS RRRQRVTALV LPGMPLQGLV SPYLGNLSFL HVLNLTNTDL TGSIPPDIGR
LSRLVVLDLG LNRLSGIIPR TIGNLTKLNS LVLVKNDLSG KIPHDLHNLG NLRHIKLGTN
YLSGIIPNQL FNNTPLLVGL GFGNNSLSGP IPPGIASCPM LEYLNLQANQ LSGPVPPTIF
NMSRLQIMSL VGNRYLTGSI PSNQSFSLPM LQRFLIGRNN FTGRIPSGLA SCKHLRVVYL
SENSFADFVP TWLSKLLHLT ILNLSGNDLI GSIPSELSNL TMLSVLDLSR CSLSGKIPDE
LGQMSQLTLL HLSENQLTGS FPAFVGNLSQ LSRLLLESNY LTGAVPTSMG DLRALEWFDI
GSNPLEGTLD FLATFSNCRQ LRYLAIYNCS FTGIIPDHIG NLSRSLTHFD AGTNHLTGGF
PAPISNLSDL KVIILYENQL RGLIPESITL LKNLEALDLT GNSLSGSIPS QIGTLNRLHI
LSLQENNFSG AIPNGIGNLS MLEIISLAYN QLSSTIPESL FHLSNLRQLF LSNNSFTGEL
YSDLGSMEAI DTVDISANSL VGSLPTSFGQ HGLLSYLDLS HNKLQGPIPE SFKKLVNLGA
LDLSLNNLSG TIPKYLANFT SLTSLNLSFN KFQGEIPDGG IFSNISAESL MGNAGLCGAL
RLGFSPCLGD SHPTNRHLLR FVLPTVIITV GVITIVLCLM FRKKNKQQPN VATSLGMADP
TSHRLVSYHE IVRATENFNM DNLLGVGSFG KVFKGKLDDG LVVAIKVLNM HFEQAVRSFD
TECQVLRMAR HRNLIQILNT CSNLDFRALL LQYMPNGSLE AQLHSGNSEP LGFIKRLDIM
LGVSEAMEYL HHHHGQVVLH CDLKPSNVLF DEDMTVHVAD FGIAKLLLGD DNSMISASMP
GTIGYMAPEL AYMGKASRKS DVFSFGIMLL EVFTGKRPMN PMFIGESSLR QWVSQAFPAR
LVVIVDEKLL QGEEISSHGF HQQTNIPPSA SPSTASNTNF LVSAFELGLE CSSDSPDHRP
SMDEVVVKLK NIKKDCSASM AARLGVPQR
//
