ID A0A1D5V1W9_WHEAT Unreviewed; 926 AA.
AC A0A1D5V1W9;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=Glutamate receptor {ECO:0000256|PIRNR:PIRNR037090};
GN ORFNames=CAMPLR22A2D_LOCUS2118 {ECO:0000313|EMBL:SPT17508.1},
GN CFC21_029315 {ECO:0000313|EMBL:KAF7015473.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS2D02G226400.1};
RN [1] {ECO:0000313|EMBL:KAF7015473.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7015473.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS2D02G226400.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS2D02G226400.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EMBL:SPT17508.1, ECO:0000313|Proteomes:UP000280104}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Thind KAUR A.;
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EnsemblPlants:TraesCS2D02G226400.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [5] {ECO:0000313|EMBL:KAF7015473.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7015473.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Glutamate-gated receptor that probably acts as non-selective
CC cation channel. {ECO:0000256|PIRNR:PIRNR037090}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the glutamate-gated ion channel (TC 1.A.10.1)
CC family. {ECO:0000256|ARBA:ARBA00008685, ECO:0000256|PIRNR:PIRNR037090}.
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DR EMBL; CM022216; KAF7015473.1; -; Genomic_DNA.
DR EMBL; LS480641; SPT17508.1; -; Genomic_DNA.
DR SMR; A0A1D5V1W9; -.
DR STRING; 4565.A0A1D5V1W9; -.
DR PaxDb; 4565-Traes_2DS_E9705A040-2; -.
DR EnsemblPlants; TraesCS2D02G226400.1; TraesCS2D02G226400.1; TraesCS2D02G226400.
DR Gramene; TraesCAD_scaffold_012487_01G000200.1; TraesCAD_scaffold_012487_01G000200.1; TraesCAD_scaffold_012487_01G000200.
DR Gramene; TraesCLE_scaffold_051621_01G000200.1; TraesCLE_scaffold_051621_01G000200.1; TraesCLE_scaffold_051621_01G000200.
DR Gramene; TraesCS2D02G226400.1; TraesCS2D02G226400.1; TraesCS2D02G226400.
DR Gramene; TraesCS2D03G0479300.1; TraesCS2D03G0479300.1.CDS; TraesCS2D03G0479300.
DR Gramene; TraesKAR2D01G0145170.1; cds.TraesKAR2D01G0145170.1; TraesKAR2D01G0145170.
DR Gramene; TraesPAR_scaffold_075625_01G000400.1; TraesPAR_scaffold_075625_01G000400.1; TraesPAR_scaffold_075625_01G000400.
DR Gramene; TraesROB_scaffold_059739_01G000200.1; TraesROB_scaffold_059739_01G000200.1; TraesROB_scaffold_059739_01G000200.
DR Gramene; TraesWEE_scaffold_049254_01G000400.1; TraesWEE_scaffold_049254_01G000400.1; TraesWEE_scaffold_049254_01G000400.
DR eggNOG; KOG1052; Eukaryota.
DR OMA; FHSHREN; -.
DR OrthoDB; 1011589at2759; -.
DR Proteomes; UP000019116; Chromosome 2D.
DR Proteomes; UP000280104; Chromosome ii.
DR Proteomes; UP000815260; Chromosome 2D.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0015276; F:ligand-gated monoatomic ion channel activity; IBA:GO_Central.
DR GO; GO:0038023; F:signaling receptor activity; IBA:GO_Central.
DR CDD; cd13686; GluR_Plant; 1.
DR CDD; cd19990; PBP1_GABAb_receptor_plant; 1.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 3.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR044440; GABAb_receptor_plant_PBP1.
DR InterPro; IPR015683; Ionotropic_Glu_rcpt.
DR InterPro; IPR001320; Iontro_rcpt_C.
DR InterPro; IPR017103; Iontropic_Glu_rcpt_pln.
DR InterPro; IPR028082; Peripla_BP_I.
DR InterPro; IPR001638; Solute-binding_3/MltF_N.
DR PANTHER; PTHR18966:SF605; GLUTAMATE RECEPTOR; 1.
DR PANTHER; PTHR18966; IONOTROPIC GLUTAMATE RECEPTOR; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR Pfam; PF00060; Lig_chan; 1.
DR Pfam; PF00497; SBP_bac_3; 2.
DR PIRSF; PIRSF037090; Iontro_Glu-like_rcpt_pln; 1.
DR PRINTS; PR01176; GABABRECEPTR.
DR SMART; SM00079; PBPe; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|PIRSR:PIRSR037090-50};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303, ECO:0000256|PIRNR:PIRNR037090};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065,
KW ECO:0000256|PIRNR:PIRNR037090};
KW Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286,
KW ECO:0000256|PIRNR:PIRNR037090};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR037090};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000256|PIRNR:PIRNR037090};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR037090}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..926
FT /note="Glutamate receptor"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5039972636"
FT TRANSMEM 593..613
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 651..671
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 836..856
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 474..815
FT /note="Ionotropic glutamate receptor C-terminal"
FT /evidence="ECO:0000259|SMART:SM00079"
FT REGION 901..926
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 905..926
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 764..819
FT /evidence="ECO:0000256|PIRSR:PIRSR037090-50"
SQ SEQUENCE 926 AA; 100717 MW; 65544E5A7D7F8E03 CRC64;
MGSAHFAAIL LCVCIIAGGA IADSQNGTNG VSRPAEVRIG ALFTFDSVIG RAAKPAIELA
VADVNADPTV LPGTKLSLLM QDTNCSGFVG TIEALQLLAK DVIAVLGPQS SAIAHIISHA
ANKLQVPLIS FAASDPTLSS LEYPYFVRAT QSDYYQMSAV ASIISQYQWR EVIAIYVDDD
YGRGGITALG DALAKKMSKI AYKAKLPPGA GRTAIQDMLM QVNEMESRVY VVHVNPDSGM
TVFSAAKSLG MMSSGYVWIA TDWLSAVIDS SGHVASDATE NTQGVIMLHQ HVADSGIQQS
LLPKLNSLTR KGNRSSFSSY TAHAYDSVWL VAHAVEQFLS AGNAVSFSAN QNLQAIKGSS
LQLDSLRVLN NGDKLLEKVL QANFTGVSGQ VQFTLDRNLI HPAYDILNIG GTGFRTIGYW
SNFSGLSVAA PENLHSVPLN STTNDIQLHS VIWPGQTAEK PRGWVFPYHG KLLRIGVPLR
TSYNEFVMQD DGPDGVKGFS VDVFKSAISL LPYPVGCTFV LFGDGLKNPS YSDLVQKVSE
NYFDAAIGDI SIVTNRTRLV DFTQPYTESG LIIVAPARET ESNAWAFLKP FTFQMWCVLG
LLFLFVGTVV WILEHRTNTE FRGTPRQQIM TVCWFSFSTM FFAHRENTSS ALGRFVLLVW
LFVVLIINSS YTASLTSLLT VQELTTGVKG LDSLISSSSA IGYQVGSFAR NYLVEELNIA
DSRLVPLNSP SDYARALELG SGNGGVAAII DELPYVEIFL SKYCKFKTVG QVFTKSGWGF
AFPRDSPLAD DLSTAILTLS ENGDLQRIHD EWLSGMKGCE SDDSGMSSNS LSLSSFWGLF
VVCGLACVVA LLIFFWRILF QYSKYNNQVE LEAAIVNRPA RLTSIKSLIS FVDKREEEVK
NALKKKPNGS QQARIGTTEE PSTLPL
//
