ID A0A1D6DU44_MAIZE Unreviewed; 449 AA.
AC A0A1D6DU44;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Putative cysteine protease RD21B {ECO:0000313|EMBL:ONM12355.1};
GN ORFNames=ZEAMMB73_Zm00001d001900 {ECO:0000313|EMBL:ONM12355.1};
OS Zea mays (Maize).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX NCBI_TaxID=4577 {ECO:0000313|EnsemblPlants:Zm00001eb066830_P002, ECO:0000313|Proteomes:UP000007305};
RN [1] {ECO:0000313|EMBL:ONM12355.1, ECO:0000313|Proteomes:UP000007305}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. B73 {ECO:0000313|EnsemblPlants:Zm00001eb066830_P002,
RC ECO:0000313|Proteomes:UP000007305};
RC TISSUE=Seedling {ECO:0000313|EMBL:ONM12355.1};
RG Maize Genome Sequencing Project;
RA Ware D.;
RT "Update maize B73 reference genome by single molecule sequencing
RT technologies.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblPlants:Zm00001eb066830_P002}
RP IDENTIFICATION.
RC STRAIN=cv. B73 {ECO:0000313|EnsemblPlants:Zm00001eb066830_P002};
RG EnsemblPlants;
RL Submitted (MAY-2021) to UniProtKB.
CC -!- SIMILARITY: Belongs to the peptidase C1 family.
CC {ECO:0000256|ARBA:ARBA00008455}.
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DR EMBL; CM007648; ONM12355.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1D6DU44; -.
DR EnsemblPlants; Zm00001eb066830_T002; Zm00001eb066830_P002; Zm00001eb066830.
DR Gramene; Zm00001eb066830_T002; Zm00001eb066830_P002; Zm00001eb066830.
DR OMA; CDRVVDQ; -.
DR Proteomes; UP000007305; Chromosome 2.
DR ExpressionAtlas; A0A1D6DU44; baseline and differential.
DR GO; GO:0008234; F:cysteine-type peptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd02248; Peptidase_C1A; 1.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR Gene3D; 2.10.25.160; Granulin; 1.
DR InterPro; IPR000118; Granulin.
DR InterPro; IPR037277; Granulin_sf.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR025661; Pept_asp_AS.
DR InterPro; IPR000169; Pept_cys_AS.
DR InterPro; IPR025660; Pept_his_AS.
DR InterPro; IPR013128; Peptidase_C1A.
DR InterPro; IPR000668; Peptidase_C1A_C.
DR InterPro; IPR039417; Peptidase_C1A_papain-like.
DR InterPro; IPR013201; Prot_inhib_I29.
DR PANTHER; PTHR12411; CYSTEINE PROTEASE FAMILY C1-RELATED; 1.
DR PANTHER; PTHR12411:SF962; CYSTEINE PROTEASE RD21C-RELATED; 1.
DR Pfam; PF00396; Granulin; 1.
DR Pfam; PF08246; Inhibitor_I29; 1.
DR Pfam; PF00112; Peptidase_C1; 1.
DR PRINTS; PR00705; PAPAIN.
DR SMART; SM00277; GRAN; 1.
DR SMART; SM00848; Inhibitor_I29; 1.
DR SMART; SM00645; Pept_C1; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR SUPFAM; SSF57277; Granulin repeat; 1.
DR PROSITE; PS00640; THIOL_PROTEASE_ASN; 1.
DR PROSITE; PS00139; THIOL_PROTEASE_CYS; 1.
DR PROSITE; PS00639; THIOL_PROTEASE_HIS; 1.
PE 1: Evidence at protein level;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022807};
KW Protease {ECO:0000313|EMBL:ONM12355.1};
KW Proteomics identification {ECO:0007829|PeptideAtlas:A0A1D6DU44};
KW Reference proteome {ECO:0000313|Proteomes:UP000007305};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Thiol protease {ECO:0000256|ARBA:ARBA00022807}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..449
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010752504"
FT DOMAIN 52..110
FT /note="Cathepsin propeptide inhibitor"
FT /evidence="ECO:0000259|SMART:SM00848"
FT DOMAIN 142..358
FT /note="Peptidase C1A papain C-terminal"
FT /evidence="ECO:0000259|SMART:SM00645"
FT DOMAIN 385..442
FT /note="Granulins"
FT /evidence="ECO:0000259|SMART:SM00277"
FT REGION 359..379
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 362..379
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 449 AA; 48219 MW; 04DD35A5FCBF7E3D CRC64;
MAALGLLLLL LLAVVGAANA AAPGGRMSII SYNEEHAARG LERTEPEART LYELWLAEHG
RAYNALGERD RRFRVFWDNL RFVDAHNERA AEHGFRLGMN QFADLTNDEF RAAYLGARIP
ASRRRGTAVG ERYRHGGGAE ELPESVDWRE KGAVAPVKNQ GQCGSCWAFS AVSSVESVNQ
IVTGEMVTLS EQELVECSTD GGNSGCNGGL MDAAFDFIIK NGGIDTEGDY PYKAVDGKCD
INRENAKVVS IDGFEDVPEN DEKSLQKAVA HQPVSVAIEA GGREFQLYKA GVFTGTCTTN
LDHGVVAVGY GTENGKDYWI VRNSWGAKWG EDGYIRMERN VNATTGKCGI AMMASYPTKK
GANPPKPSPT PPTPPPPPVA PDNVCDENFS CAAGSTCCCA FGFRNVCLVW GCCPMEGATC
CKDHASCCPP GYPVCNVRAG TCSVSKNSP
//
