ID A0A1D6EGD3_MAIZE Unreviewed; 238 AA.
AC A0A1D6EGD3;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=protein-S-isoprenylcysteine alpha-carbonyl methylesterase {ECO:0000256|ARBA:ARBA00038928};
DE EC=3.1.1.n2 {ECO:0000256|ARBA:ARBA00038928};
GN ORFNames=ZEAMMB73_Zm00001d004576 {ECO:0000313|EMBL:ONM19229.1};
OS Zea mays (Maize).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX NCBI_TaxID=4577 {ECO:0000313|EMBL:ONM19229.1};
RN [1] {ECO:0000313|EMBL:ONM19229.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Seedling {ECO:0000313|EMBL:ONM19229.1};
RG Maize Genome Sequencing Project;
RA Ware D.;
RT "Update maize B73 reference genome by single molecule sequencing
RT technologies.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine methyl
CC ester + H2O = [protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine +
CC H(+) + methanol; Xref=Rhea:RHEA:48520, Rhea:RHEA-COMP:12125,
CC Rhea:RHEA-COMP:12126, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:17790, ChEBI:CHEBI:90510, ChEBI:CHEBI:90511; EC=3.1.1.n2;
CC Evidence={ECO:0000256|ARBA:ARBA00035789};
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004586}. Golgi apparatus membrane
CC {ECO:0000256|ARBA:ARBA00004653}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004653}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the AB hydrolase superfamily. Isoprenylcysteine
CC methylesterase family. {ECO:0000256|ARBA:ARBA00038028}.
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DR EMBL; CM007648; ONM19229.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1D6EGD3; -.
DR SMR; A0A1D6EGD3; -.
DR STRING; 4577.A0A1D6EGD3; -.
DR InParanoid; A0A1D6EGD3; -.
DR ExpressionAtlas; A0A1D6EGD3; baseline and differential.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR049492; BD-FAE-like_dom.
DR PANTHER; PTHR48081; AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C; 1.
DR PANTHER; PTHR48081:SF36; ALPHA BETA-HYDROLASES SUPERFAMILY PROTEIN; 1.
DR Pfam; PF20434; BD-FAE; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 69..145
FT /note="BD-FAE-like"
FT /evidence="ECO:0000259|Pfam:PF20434"
SQ SEQUENCE 238 AA; 26167 MW; 95A556E2EFF88877 CRC64;
MTESLVQNKP GMASIKEMPV VQDGPPPGGF APVRFAHRIP TSARGTRGTR SLSLMWLIFS
YKAWGALLGR RLAERGIIVA CIDYRNFPQG TISDMVSDAS EAISFICNNV VSFGGDPNKT
YLMGQSAGAH IVACTLLEQA IKESKGENTY WNVAQIKAYF GLSGGYNIQN LVDHFHERGV
FIVQYFSADK LPSVALFSEH IIDCICLSVS RSLMLCSTFA KLIKEDMNKQ PKMESSLT
//
