ID   A0A1D6ESP8_MAIZE        Unreviewed;      1147 AA.
AC   A0A1D6ESP8;
DT   30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2016, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   RecName: Full=ATP-dependent DNA helicase {ECO:0000256|RuleBase:RU363044};
DE            EC=3.6.4.12 {ECO:0000256|RuleBase:RU363044};
GN   ORFNames=ZEAMMB73_Zm00001d006074 {ECO:0000313|EMBL:ONM22734.1};
OS   Zea mays (Maize).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC   Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX   NCBI_TaxID=4577 {ECO:0000313|EMBL:ONM22734.1};
RN   [1] {ECO:0000313|EMBL:ONM22734.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   TISSUE=Seedling {ECO:0000313|EMBL:ONM22734.1};
RG   Maize Genome Sequencing Project;
RA   Ware D.;
RT   "Update maize B73 reference genome by single molecule sequencing
RT   technologies.";
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC         Evidence={ECO:0000256|RuleBase:RU363044};
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|RuleBase:RU363044};
CC   -!- SIMILARITY: Belongs to the helicase family.
CC       {ECO:0000256|RuleBase:RU363044}.
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DR   EMBL; CM007648; ONM22734.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1D6ESP8; -.
DR   STRING; 4577.A0A1D6ESP8; -.
DR   InParanoid; A0A1D6ESP8; -.
DR   ExpressionAtlas; A0A1D6ESP8; baseline.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0000723; P:telomere maintenance; IEA:InterPro.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR010285; DNA_helicase_pif1-like.
DR   InterPro; IPR025476; Helitron_helicase-like.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR049163; Pif1-like_2B_dom.
DR   PANTHER; PTHR10492:SF94; ATP-DEPENDENT DNA HELICASE; 1.
DR   PANTHER; PTHR10492; UNCHARACTERIZED; 1.
DR   Pfam; PF14214; Helitron_like_N; 1.
DR   Pfam; PF05970; PIF1; 1.
DR   Pfam; PF21530; Pif1_2B_dom; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|RuleBase:RU363044};
KW   DNA damage {ECO:0000256|RuleBase:RU363044};
KW   DNA recombination {ECO:0000256|RuleBase:RU363044};
KW   DNA repair {ECO:0000256|RuleBase:RU363044};
KW   Helicase {ECO:0000256|RuleBase:RU363044};
KW   Hydrolase {ECO:0000256|RuleBase:RU363044};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU363044}.
FT   DOMAIN          289..356
FT                   /note="Helitron helicase-like"
FT                   /evidence="ECO:0000259|Pfam:PF14214"
FT   DOMAIN          1098..1144
FT                   /note="DNA helicase Pif1-like 2B"
FT                   /evidence="ECO:0000259|Pfam:PF21530"
SQ   SEQUENCE   1147 AA;  131737 MW;  CB15A41EDE87F2F7 CRC64;
     MEVPTYTSEV VHSTADVSEP DSSSDNACDW VIPEYTSTPF MSASTQTEDV GSPDMSTEPL
     RRKHHVLPGE RQAILARQNK KFEANIARNV ATLTEDTISD IGQMDDSTQP GSTIEINNTI
     DDDDEGVIFR EDNDENEGYL FADEDTNEDF DIDGTQDQSV VTDVPDPYDK VYSNIPEETH
     MLKHVPDCGY CTAKKFEYEP PGFCCREHKH LELYFYDDDP SLEHRYRKCR EDQIQKDQEV
     IKQIVGILRG NPYSEHLRSM GHVENLADYH IALNLDQTLN QKTYNTPLTS EDEIRRELLP
     GQTPQDRPDL VVRVFHAKLQ ELKHRLTKQD ILGKVRAYVY VVEFQKRGLP HAHFLLIMQR
     KYKLTCPEQY DLLISAEIPS NKYPELRKMV IKHMMHGPCG SLNPNCPCTK GRASCKNQYP
     RHFHEATMQG KDSYPNYRRR DDGRKEKVRG CELDNRWVVP YNPYLLRLFN CHINVEECGS
     IKAVKYLFKY IYKGHDRVSV VMRDAGKENG DVDEIQQYRD ARWVTPPEAL RRIYGFELSQ
     NSPSVMQLQL HLPNMHMVTF HERQMVERVV NRPGADRSMI TAYFEANKLY EEARGILYRD
     FPEWYTWQQG KVWQRRKQNM GGQVGRIVSA LPSEGERFYL RLLLNHVTGA TSYVDLRTVD
     TDTLPSFHEA AQRRGLLEAD NTIDECLNEA ALYQMPSALR RLFATILVFC EPNDVAELWQ
     RHLDTMSEYY HRITQSKTHL QQMVLIDIRN MLQSMGKDIK TFPLPAIIDR YDDSQGIDRE
     IYEEEIIEAT TEDVALQETL NEEQKSAYEK ILSVVDTSNG GVFFVDGPSG TRKTYLYKAL
     LAVLRSQDKI AVATAISRVA ASIMPGGRTA HSRFKIPLTM DDGAICTFTK QSGTSKLLQK
     ASLIIWDEAS MAKRQSIEAL DNSMRDIMGR PDLPFGGKTI VFGGDFRQVL PVVRKGSRAQ
     IVAASLRSSY LWESMCHLKL VRNMRAKSDP WFAEYLLRVG GGTEEVNNDG DVRLPDEVCV
     PYTGDDRDLD RLIDDIYPSL NENMSNTSYI TSRAILTTRN DWVDMINMRM IDRFQREQMM
     YHSFDTAVDD PNNYYPSEFL NTLTPNGLPP HVLKLKIGCP IMLLRNIDPA NGLCNGTRLV
     VRGFQKK
//