ID   A0A1D6H0A6_MAIZE        Unreviewed;       729 AA.
AC   A0A1D6H0A6;
DT   30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2016, sequence version 1.
DT   27-MAR-2024, entry version 36.
DE   RecName: Full=Terpene cyclase/mutase family member {ECO:0000256|RuleBase:RU362003};
DE            EC=5.4.99.- {ECO:0000256|RuleBase:RU362003};
GN   ORFNames=ZEAMMB73_Zm00001d015234 {ECO:0000313|EMBL:AQK68374.1};
OS   Zea mays (Maize).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC   Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX   NCBI_TaxID=4577 {ECO:0000313|EMBL:AQK68374.1};
RN   [1] {ECO:0000313|EMBL:AQK68374.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Seedling {ECO:0000313|EMBL:AQK68374.1};
RG   Maize Genome Sequencing Project;
RA   Ware D.;
RT   "Update maize B73 reference genome by single molecule sequencing
RT   technologies.";
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the terpene cyclase/mutase family.
CC       {ECO:0000256|ARBA:ARBA00009755, ECO:0000256|RuleBase:RU362003}.
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DR   EMBL; CM000781; AQK68374.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1D6H0A6; -.
DR   ExpressionAtlas; A0A1D6H0A6; baseline and differential.
DR   GO; GO:0005811; C:lipid droplet; IEA:InterPro.
DR   GO; GO:0016871; F:cycloartenol synthase activity; IEA:UniProt.
DR   GO; GO:1901362; P:organic cyclic compound biosynthetic process; IEA:UniProt.
DR   GO; GO:0016104; P:triterpenoid biosynthetic process; IEA:InterPro.
DR   CDD; cd02892; SQCY_1; 1.
DR   Gene3D; 1.50.10.20; -; 2.
DR   InterPro; IPR032696; SQ_cyclase_C.
DR   InterPro; IPR032697; SQ_cyclase_N.
DR   InterPro; IPR018333; Squalene_cyclase.
DR   InterPro; IPR002365; Terpene_synthase_CS.
DR   InterPro; IPR008930; Terpenoid_cyclase/PrenylTrfase.
DR   NCBIfam; TIGR01787; squalene_cyclas; 1.
DR   PANTHER; PTHR11764:SF20; LANOSTEROL SYNTHASE; 1.
DR   PANTHER; PTHR11764; TERPENE CYCLASE/MUTASE FAMILY MEMBER; 1.
DR   Pfam; PF13243; SQHop_cyclase_C; 1.
DR   Pfam; PF13249; SQHop_cyclase_N; 1.
DR   SFLD; SFLDG01016; Prenyltransferase_Like_2; 1.
DR   SUPFAM; SSF48239; Terpenoid cyclases/Protein prenyltransferases; 2.
DR   PROSITE; PS01074; TERPENE_SYNTHASES; 1.
PE   3: Inferred from homology;
KW   Isomerase {ECO:0000256|RuleBase:RU362003};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          127..345
FT                   /note="Squalene cyclase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13249"
FT   DOMAIN          381..718
FT                   /note="Squalene cyclase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13243"
SQ   SEQUENCE   729 AA;  82595 MW;  922340A298F30F86 CRC64;
     MWRLRIAEGG GDPWLRTKNA HVGRQVWEFD AAADPDPAVD AARRAFVATR GHLKHSADLL
     MRIQFAKENS IELHLPGIKL GEHEDVTEEA VLTTLKRAIS RFSTLQAHDG HWPGDYGGPM
     FLMPGLNEDG GWGLHIEGPS TMFGSALTYV ILRLLGEGPD SGDGAMEKGR NWILDHGGAT
     YITSWGKFWL SVLGVFEWSG NNPVPPEVWL LPYLLPFHPG RMWCHCRMVY LPMCYIYGKR
     FVGRITPLLL ELRKELFKDP YSKIDWDKAR NLCAKEDLYY PHPFVQDVLW ATLHKFVEPV
     MMHWPGSKLR EKALETVMQH VHYEDENTRY ICIGPVNKVL NMLACWIEDP NSEAFKLHIP
     RVYDYLWLAE DGMKMQGYNG SQLWDTAFTV QAIVATNLIE EFGPTLKLAH NYIKNSQVLD
     DCPGDLNDWY RHTSKGAWPF STADHGWPIS DCTAEGLKAS LLLSRISPKI VGEPMEANRF
     YDAVSCLMSY MNDNGGFATY ELTRSYPWLE LINPAETFGD IVIDYPYVEC TSAAIQALTS
     FKKLYPGHRR KEVDNCISKA SNFIESIQKS DGSWYGSWAV CFTYGTWFGV KGLIAAGRTF
     ENSPAIRKAC DFLLSKELPS GGWGESYLSS QDQVYTNLKG NRPHAVNTSW AMLALIDAGQ
     AERDPTPLHR AAKVLINLQS EDGEFPQQEI IGVFNKNCMI SYSQYRNIFP IWALGEYRCR
     VLGAGKPWR
//