ID A0A1D6HCD2_MAIZE Unreviewed; 1016 AA.
AC A0A1D6HCD2;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 1.
DT 24-JAN-2024, entry version 36.
DE SubName: Full=Embryo defective 2423 {ECO:0000313|EMBL:AQK72362.1};
GN Name=100192364 {ECO:0000313|EnsemblPlants:Zm00001eb246300_P001};
GN ORFNames=ZEAMMB73_Zm00001d017114 {ECO:0000313|EMBL:AQK72362.1};
OS Zea mays (Maize).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX NCBI_TaxID=4577 {ECO:0000313|EMBL:AQK72362.1};
RN [1] {ECO:0000313|EnsemblPlants:Zm00001eb246300_P001, ECO:0000313|Proteomes:UP000007305}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. B73 {ECO:0000313|EnsemblPlants:Zm00001eb246300_P001,
RC ECO:0000313|Proteomes:UP000007305};
RX PubMed=19965430; DOI=10.1126/science.1178534;
RA Schnable P.S., Ware D., Fulton R.S., Stein J.C., Wei F., Pasternak S.,
RA Liang C., Zhang J., Fulton L., Graves T.A., Minx P., Reily A.D.,
RA Courtney L., Kruchowski S.S., Tomlinson C., Strong C., Delehaunty K.,
RA Fronick C., Courtney B., Rock S.M., Belter E., Du F., Kim K., Abbott R.M.,
RA Cotton M., Levy A., Marchetto P., Ochoa K., Jackson S.M., Gillam B.,
RA Chen W., Yan L., Higginbotham J., Cardenas M., Waligorski J., Applebaum E.,
RA Phelps L., Falcone J., Kanchi K., Thane T., Scimone A., Thane N., Henke J.,
RA Wang T., Ruppert J., Shah N., Rotter K., Hodges J., Ingenthron E.,
RA Cordes M., Kohlberg S., Sgro J., Delgado B., Mead K., Chinwalla A.,
RA Leonard S., Crouse K., Collura K., Kudrna D., Currie J., He R.,
RA Angelova A., Rajasekar S., Mueller T., Lomeli R., Scara G., Ko A.,
RA Delaney K., Wissotski M., Lopez G., Campos D., Braidotti M., Ashley E.,
RA Golser W., Kim H., Lee S., Lin J., Dujmic Z., Kim W., Talag J., Zuccolo A.,
RA Fan C., Sebastian A., Kramer M., Spiegel L., Nascimento L., Zutavern T.,
RA Miller B., Ambroise C., Muller S., Spooner W., Narechania A., Ren L.,
RA Wei S., Kumari S., Faga B., Levy M.J., McMahan L., Van Buren P.,
RA Vaughn M.W., Ying K., Yeh C.-T., Emrich S.J., Jia Y., Kalyanaraman A.,
RA Hsia A.-P., Barbazuk W.B., Baucom R.S., Brutnell T.P., Carpita N.C.,
RA Chaparro C., Chia J.-M., Deragon J.-M., Estill J.C., Fu Y., Jeddeloh J.A.,
RA Han Y., Lee H., Li P., Lisch D.R., Liu S., Liu Z., Nagel D.H., McCann M.C.,
RA SanMiguel P., Myers A.M., Nettleton D., Nguyen J., Penning B.W.,
RA Ponnala L., Schneider K.L., Schwartz D.C., Sharma A., Soderlund C.,
RA Springer N.M., Sun Q., Wang H., Waterman M., Westerman R., Wolfgruber T.K.,
RA Yang L., Yu Y., Zhang L., Zhou S., Zhu Q., Bennetzen J.L., Dawe R.K.,
RA Jiang J., Jiang N., Presting G.G., Wessler S.R., Aluru S.,
RA Martienssen R.A., Clifton S.W., McCombie W.R., Wing R.A., Wilson R.K.;
RT "The B73 maize genome: complexity, diversity, and dynamics.";
RL Science 326:1112-1115(2009).
RN [2] {ECO:0000313|EMBL:AQK72362.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Seedling {ECO:0000313|EMBL:AQK72362.1};
RG Maize Genome Sequencing Project;
RA Ware D.;
RT "Update maize B73 reference genome by single molecule sequencing
RT technologies.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblPlants:Zm00001eb246300_P001}
RP IDENTIFICATION.
RC STRAIN=cv. B73 {ECO:0000313|EnsemblPlants:Zm00001eb246300_P001};
RG EnsemblPlants;
RL Submitted (MAY-2021) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TEL2 family.
CC {ECO:0000256|ARBA:ARBA00006133}.
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DR EMBL; CM000781; AQK72355.1; -; Genomic_DNA.
DR EMBL; CM000781; AQK72362.1; -; Genomic_DNA.
DR RefSeq; NP_001296784.1; NM_001309855.1.
DR AlphaFoldDB; A0A1D6HCD2; -.
DR IntAct; A0A1D6HCD2; 2.
DR STRING; 4577.A0A1D6HCD2; -.
DR PaxDb; 4577-GRMZM2G144166_P02; -.
DR EnsemblPlants; Zm00001eb246300_T001; Zm00001eb246300_P001; Zm00001eb246300.
DR GeneID; 100192364; -.
DR Gramene; Zm00001eb246300_T001; Zm00001eb246300_P001; Zm00001eb246300.
DR KEGG; zma:100192364; -.
DR eggNOG; KOG4346; Eukaryota.
DR InParanoid; A0A1D6HCD2; -.
DR OrthoDB; 318921at2759; -.
DR Proteomes; UP000007305; Chromosome 5.
DR ExpressionAtlas; A0A1D6HCD2; baseline and differential.
DR GO; GO:0070209; C:ASTRA complex; IBA:GO_Central.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0051879; F:Hsp90 protein binding; IBA:GO_Central.
DR GO; GO:0042162; F:telomeric DNA binding; IBA:GO_Central.
DR GO; GO:0050821; P:protein stabilization; IBA:GO_Central.
DR GO; GO:0007004; P:telomere maintenance via telomerase; IBA:GO_Central.
DR Gene3D; 1.25.40.720; Telomere length regulation protein 2, C-terminal domain; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR038528; TEL2_C_sf.
DR InterPro; IPR019337; Telomere_length_regulation_dom.
DR PANTHER; PTHR15830; TELOMERE LENGTH REGULATION PROTEIN TEL2 FAMILY MEMBER; 1.
DR PANTHER; PTHR15830:SF10; TELOMERE LENGTH REGULATION PROTEIN TEL2 HOMOLOG; 1.
DR Pfam; PF10193; Telomere_reg-2; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|PeptideAtlas:A0A1D6HCD2};
KW Reference proteome {ECO:0000313|Proteomes:UP000007305}.
FT DOMAIN 634..745
FT /note="Telomere length regulation protein conserved"
FT /evidence="ECO:0000259|Pfam:PF10193"
FT REGION 543..563
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1016 AA; 113381 MW; E6BAEADD7F025D70 CRC64;
MASTRSSSLP SRGATDGEKR LEALALGRVA EAADAVASAA CAGEVVRAIH AVASLLFPVD
SEAVAGTVEE PFRSQILDAV TVTLSNEERE SWRHAFYHGP AFPTMSKILL GNVALKWLPK
INVSARQEIY DSFFVKGPPT EVIQALVPAL SEKEFSKEDH QTFCLNLERL LILWLLDNKG
VFQIVVDFIC SKKHGEDILS PDKTISVSRV AQLLASVPDK ARLGASAALT SPSFFKHVVS
QLLAGAEATT IELAADKEAN EHYVLSSMFH FVGEVLSRVC RRGSTGVLVA ELIPKVRNHI
HRCVPPDHRA TIPEMVQHVC QSQFWFNMVE AMRDQHSIER LTEELLRQLA SQHISDEEAY
WILWTLFNQS FKRLTVMRAM FVDKFLLWKT FPLCCLRWIL HYAVFECPPN STTEILMQRT
PNFFGILQSL VSIWSRKEFI QSYSVEQQAY ITAAIGLCLE KLTKKELETT KDVLNSILQG
VSCRLESPID LLRKMASAVA LTFSKVVDPK NPLYLDDNCC ENVDWDFGVL SPKEFKAPLD
AVETKTKPKT RENKKKAGEK KTKAIKRDIP DVRAKIVEIN SIDHDQMSDT ATNGQFEEEE
CDEEDMNMDA YSDSSLEPYD LSDDDTDLQK KISHLSDLAA ALRKPDDPDG VENALNYAEK
LVRASPDELR YNSGDLVRAL VHVRCSDVAM EGEEDSAEEK RQKALVSLLV TCPFESLDVL
TKLLYSSSVD IGQRILIIDA MTEAAQELAE TKTVKIEQRR GNLITDTSPS WLVPSNIGPP
GAGPWREVSE PGTLLSWSHR YEREVPSKSG QLKSGKSRKW GLGKAKDLQV EWSKNRFPLY
AAAFMLPVMQ GYDKRSHGVD LLNRDFVVLG KLIYMLGVCM KSMAMHPEAS ALAPALLDMI
RSRDISRHAE AYVRRSVLFA ASCILISLHP SYVASSLIEG NQDISTGLEW IRTWALQIAE
ADPDTECSSM AMTCLRLHSE MALQTSRALE SANHSKTGRA IPSKLDSIIL PFGNMM
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