ID   A0A1D6HDU8_MAIZE        Unreviewed;      1137 AA.
AC   A0A1D6HDU8;
DT   30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2016, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   SubName: Full=Regulator of nonsense transcripts UPF2 {ECO:0000313|EMBL:AQK72837.1};
DE   Flags: Fragment;
GN   ORFNames=ZEAMMB73_Zm00001d017303 {ECO:0000313|EMBL:AQK72837.1};
OS   Zea mays (Maize).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC   Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX   NCBI_TaxID=4577 {ECO:0000313|EMBL:AQK72837.1};
RN   [1] {ECO:0000313|EMBL:AQK72837.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Seedling {ECO:0000313|EMBL:AQK72837.1};
RG   Maize Genome Sequencing Project;
RA   Ware D.;
RT   "Update maize B73 reference genome by single molecule sequencing
RT   technologies.";
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR   EMBL; CM000781; AQK72837.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1D6HDU8; -.
DR   ExpressionAtlas; A0A1D6HDU8; baseline and differential.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:InterPro.
DR   Gene3D; 1.25.40.180; -; 3.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR003890; MIF4G-like_typ-3.
DR   InterPro; IPR039762; Nmd2/UPF2.
DR   InterPro; IPR007193; Upf2/Nmd2_C.
DR   PANTHER; PTHR12839; NONSENSE-MEDIATED MRNA DECAY PROTEIN 2 UP-FRAMESHIFT SUPPRESSOR 2; 1.
DR   PANTHER; PTHR12839:SF7; REGULATOR OF NONSENSE TRANSCRIPTS 2; 1.
DR   Pfam; PF02854; MIF4G; 3.
DR   Pfam; PF04050; Upf2; 1.
DR   SMART; SM00543; MIF4G; 2.
DR   SUPFAM; SSF48371; ARM repeat; 3.
PE   4: Predicted;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        1113..1130
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          388..576
FT                   /note="MIF4G"
FT                   /evidence="ECO:0000259|SMART:SM00543"
FT   DOMAIN          591..792
FT                   /note="MIF4G"
FT                   /evidence="ECO:0000259|SMART:SM00543"
FT   REGION          234..268
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          300..381
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          813..931
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          960..995
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1053..1091
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        243..260
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        813..837
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        853..889
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        890..907
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        908..931
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1057..1077
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1137
FT                   /evidence="ECO:0000313|EMBL:AQK72837.1"
SQ   SEQUENCE   1137 AA;  128598 MW;  773F5D0818571249 CRC64;
     MDELKSVNLS KFVSEAVSYI CEAKLRSADI QAAVQVCSLL HQRYKDFSPC LIQGLLKVFF
     PGKSVDDLDA DKNSRAMKKR STLKLLIELY FVGIVEDASI FVNIIKDLTS AEHLKDREGT
     QTNLSLLSTF ARQGKFFLGL QPHGQEAYDE FFKELNVTAE QKKFFKKALN SYYDTVAELL
     QSEHVSLRLM EAENAKVLSA KGELSDENTA SYEKLRKSFD QLLRGVSSLA ESLDMQPPVM
     PDDGNTTRVT TRTDALPSSG KDSSALEPIW DDEDTKAFYE SLPDLRAFVP AVLLGEVEPK
     SNEQHAKGRE QSSESTSEQE TELHDDFQTS ATEHQLEVKL DGGVKESDDK DKEKGKDGEK
     EKSKEKDLDK KNDREKEKGR AMDGASLDNI LQRLPGCVSR DLIDQLTVEF CYLNSKANRK
     KLARALFNVN RTSLELLPYY SRLVATLSTC MKDVPSMLLS MLEEEFNFLI NKKDQINIET
     KIKNIRFIGE LCKFKMAPPA LVFSCLKSCL DDFSHHNIDV ACNLLETCGR FLYRSPETTI
     RMANMLEILM RLKNVKNLDP RHSTLVENAY YLCKPPERSA RISKVRPPLH QYIRKLLFSD
     LDKSSVEHVL RQLRKLPWAE CQQYLLKCFL KVHKGKYSQV HLIALLTASL SRYHDDFAVA
     VVDEVLEEIR VGLELNDYGM QQRRLAHMRF LGELYSYKHI DSSVVFDTLY LIIVFGHGTP
     EQDVLDPPED CFRIRLIITL LQTCGHYFSK GSSKRKLDKF LLHFQRYIIS KGPLPLDIEF
     DIQDLFGELR PNMSRYLSIE ELVAALVELE ENERSAPVEK VENERHSDNE SHKRQARDAG
     PSVNGGSAAN GIEENGKDHE IADSESYSDS GSIDGREDED ILSEDKSNDG SDNEGDDEDD
     GIPVGSDEDE NVEVRQKVMK VDPKEQEDFD RELKALLQES LESRKSEARS RLPLNMMVPM
     NVLEGSSKDS RATESESGEE TVDEEGGNAG GSSKVRVKVL MKKGHKQQTR QMLIPADSSI
     VRSTKQQEAA ELEEKQSIKR RILEYNEREE EELNGASQMG NWGQGATNTS SIRSGGRGSW
     DGSARGGGRQ RHHIAGSGGF YHSYGRRRTV SCVSYFVLSF FLAGPCFSLF NRLTIRL
//