ID A0A1D6HQP8_MAIZE Unreviewed; 959 AA.
AC A0A1D6HQP8;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=Glutamate receptor {ECO:0000256|PIRNR:PIRNR037090};
GN Name=103631863 {ECO:0000313|EnsemblPlants:Zm00001eb298150_P001};
GN ORFNames=ZEAMMB73_Zm00001d018614 {ECO:0000313|EMBL:ONM50886.1};
OS Zea mays (Maize).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX NCBI_TaxID=4577 {ECO:0000313|EMBL:ONM50886.1};
RN [1] {ECO:0000313|EMBL:ONM50886.1, ECO:0000313|Proteomes:UP000007305}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. B73 {ECO:0000313|EnsemblPlants:Zm00001eb298150_P001,
RC ECO:0000313|Proteomes:UP000007305};
RC TISSUE=Seedling {ECO:0000313|EMBL:ONM50886.1};
RG Maize Genome Sequencing Project;
RA Ware D.;
RT "Update maize B73 reference genome by single molecule sequencing
RT technologies.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblPlants:Zm00001eb298150_P001}
RP IDENTIFICATION.
RC STRAIN=cv. B73 {ECO:0000313|EnsemblPlants:Zm00001eb298150_P001};
RG EnsemblPlants;
RL Submitted (MAY-2021) to UniProtKB.
CC -!- FUNCTION: Glutamate-gated receptor that probably acts as non-selective
CC cation channel. {ECO:0000256|PIRNR:PIRNR037090}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the glutamate-gated ion channel (TC 1.A.10.1)
CC family. {ECO:0000256|ARBA:ARBA00008685, ECO:0000256|PIRNR:PIRNR037090}.
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DR EMBL; CM007650; ONM50886.1; -; Genomic_DNA.
DR RefSeq; XP_008651910.1; XM_008653688.1.
DR AlphaFoldDB; A0A1D6HQP8; -.
DR SMR; A0A1D6HQP8; -.
DR STRING; 4577.A0A1D6HQP8; -.
DR PaxDb; 4577-GRMZM2G020104_P01; -.
DR EnsemblPlants; Zm00001eb298150_T001; Zm00001eb298150_P001; Zm00001eb298150.
DR EnsemblPlants; Zm00001eb298150_T002; Zm00001eb298150_P002; Zm00001eb298150.
DR GeneID; 103631863; -.
DR Gramene; Zm00001eb298150_T001; Zm00001eb298150_P001; Zm00001eb298150.
DR Gramene; Zm00001eb298150_T002; Zm00001eb298150_P002; Zm00001eb298150.
DR KEGG; zma:103631863; -.
DR eggNOG; KOG1052; Eukaryota.
DR InParanoid; A0A1D6HQP8; -.
DR OMA; AYKKHQI; -.
DR OrthoDB; 1011589at2759; -.
DR Proteomes; UP000007305; Chromosome 7.
DR ExpressionAtlas; A0A1D6HQP8; baseline and differential.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0015276; F:ligand-gated monoatomic ion channel activity; IBA:GO_Central.
DR GO; GO:0038023; F:signaling receptor activity; IBA:GO_Central.
DR CDD; cd13686; GluR_Plant; 1.
DR CDD; cd19990; PBP1_GABAb_receptor_plant; 1.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 3.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR044440; GABAb_receptor_plant_PBP1.
DR InterPro; IPR019594; Glu/Gly-bd.
DR InterPro; IPR015683; Ionotropic_Glu_rcpt.
DR InterPro; IPR001320; Iontro_rcpt_C.
DR InterPro; IPR017103; Iontropic_Glu_rcpt_pln.
DR InterPro; IPR028082; Peripla_BP_I.
DR InterPro; IPR001638; Solute-binding_3/MltF_N.
DR PANTHER; PTHR18966:SF487; GLUTAMATE RECEPTOR 3.4; 1.
DR PANTHER; PTHR18966; IONOTROPIC GLUTAMATE RECEPTOR; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR Pfam; PF00060; Lig_chan; 1.
DR Pfam; PF10613; Lig_chan-Glu_bd; 1.
DR Pfam; PF00497; SBP_bac_3; 1.
DR PIRSF; PIRSF037090; Iontro_Glu-like_rcpt_pln; 1.
DR PRINTS; PR01176; GABABRECEPTR.
DR SMART; SM00079; PBPe; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|PIRSR:PIRSR037090-50};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303, ECO:0000256|PIRNR:PIRNR037090};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065,
KW ECO:0000256|PIRNR:PIRNR037090};
KW Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286,
KW ECO:0000256|PIRNR:PIRNR037090};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR037090};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000256|PIRNR:PIRNR037090};
KW Reference proteome {ECO:0000313|Proteomes:UP000007305};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR037090}.
FT SIGNAL 1..38
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 39..959
FT /note="Glutamate receptor"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5011173541"
FT TRANSMEM 610..629
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 671..697
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 851..871
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 487..830
FT /note="Ionotropic glutamate receptor C-terminal"
FT /evidence="ECO:0000259|SMART:SM00079"
FT REGION 926..959
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 942..959
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 779..833
FT /evidence="ECO:0000256|PIRSR:PIRSR037090-50"
SQ SEQUENCE 959 AA; 103572 MW; 0C5D8D1A6E291A21 CRC64;
MASPLSSSSS STSTSTSTLL RLICLCTALP VALQAAAARP PNVTVGALFT FDSVIGRSAR
TAIQLAVDDV NRDPAVLRDT NLSVIFQDTK CSGFVGTIQA LELMERHVVA VVGPQSSGIA
HVVSHVANQL RVPLLSFAAT DPALASSQYP YFVRATHDDR FQMAAVADVV AHHGWREVTA
VYVDNDYGRG GVVALGDALE ALRARVSYRA AFPPGADRAA LADLLVRANM MESRVFVVHA
SPDSGLDVFA AARSLDMMAT GYVWIATDWL AAAIDAAGAG AAAAAGNIQG VLMLRQYTPD
SDAKASLVSR FAAKQYINAY GLFAYDSVWM AARAIDQFLD DNASGGNVSF SADRNIRDAN
GSALGLSALR VFDQGEQLLR KVMLANFTGV TGSVRFQLDA DGSGGATLIN PAYEILNVGG
TGVRRVAYWS NYTRLSVEAP RLLADGGPPP NSNNTTTQQQ QQMYSVIWPG DTTAKPRGWV
FPNNGKPLRI GVPYRTTYKQ FVSKDRSSPD GVSGYCVDVF NAAVALLPYP VPASFVLFGD
GVKNPSYNDL VQRVADGFFD AAVGDISIVT NRTRVVDFTQ PYVESGLVIV STVKAKNSNE
WAFLKPFTPG MWAIIGAFFL FVGAVVWILE HRFNPEFRGS PRRQMVTIFW FSFSTMFFAH
RENTVSTLGR FVLIIWLFVV LIINSSYTAS LTSILTVQQL STGIQGLDSL LSSNDPIGYQ
VGSFARSYMM DELGVPASRL RELAIDGYAG SLQRGPSNGG VAAIVDELPY VELFLSTNCQ
FRTVGQEFTK SGWGFAFQRD SPLAVDLSTA ILTLSENGDL QRIHDKWLSP GTCASQSTDG
VGADRLNLGS FWGLFLICGV ACFVALLIYF ARILCQFCKY HGHGTTDGAG PFPVPERSLR
RPARLTSIRD LMSFVDMKEA EVKRAIRSRS DRRLDGSMGG RSYTSEGPSL SRPSSMSPV
//
