ID   A0A1D6I1C4_MAIZE        Unreviewed;       254 AA.
AC   A0A1D6I1C4;
DT   30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2016, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   SubName: Full=Sodium/hydrogen exchanger {ECO:0000313|EMBL:ONM54020.1};
GN   ORFNames=ZEAMMB73_Zm00001d019978 {ECO:0000313|EMBL:ONM54020.1};
OS   Zea mays (Maize).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC   Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX   NCBI_TaxID=4577 {ECO:0000313|EMBL:ONM54020.1};
RN   [1] {ECO:0000313|EMBL:ONM54020.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   TISSUE=Seedling {ECO:0000313|EMBL:ONM54020.1};
RG   Maize Genome Sequencing Project;
RA   Ware D.;
RT   "Update maize B73 reference genome by single molecule sequencing
RT   technologies.";
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H(+)(out) + K(+)(in) = H(+)(in) + K(+)(out);
CC         Xref=Rhea:RHEA:29467, ChEBI:CHEBI:15378, ChEBI:CHEBI:29103;
CC         Evidence={ECO:0000256|ARBA:ARBA00033682};
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H(+)(out) + Na(+)(in) = H(+)(in) + Na(+)(out);
CC         Xref=Rhea:RHEA:29419, ChEBI:CHEBI:15378, ChEBI:CHEBI:29101;
CC         Evidence={ECO:0000256|ARBA:ARBA00033620};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CM007650; ONM54020.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1D6I1C4; -.
DR   ExpressionAtlas; A0A1D6I1C4; baseline and differential.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015385; F:sodium:proton antiporter activity; IEA:InterPro.
DR   InterPro; IPR006153; Cation/H_exchanger.
DR   InterPro; IPR018422; Cation/H_exchanger_CPA1.
DR   PANTHER; PTHR10110; SODIUM/HYDROGEN EXCHANGER; 1.
DR   PANTHER; PTHR10110:SF191; SODIUM_HYDROGEN EXCHANGER; 1.
DR   Pfam; PF00999; Na_H_Exchanger; 1.
PE   4: Predicted;
KW   Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Potassium {ECO:0000256|ARBA:ARBA00022958};
KW   Potassium transport {ECO:0000256|ARBA:ARBA00022538};
KW   Sodium {ECO:0000256|ARBA:ARBA00023053};
KW   Sodium transport {ECO:0000256|ARBA:ARBA00023201};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW   Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   DOMAIN          2..166
FT                   /note="Cation/H+ exchanger"
FT                   /evidence="ECO:0000259|Pfam:PF00999"
SQ   SEQUENCE   254 AA;  28428 MW;  26AED9EC0F9C7FFB CRC64;
     MLAEGLGLSG IVSILFTGMV MKHYTYSNLS DNSQRFVSAF FHLLSSLAET FVFIYMGFDI
     AMEEHSWSHV GFIFFSIIFI VVARAANVFS CAYLVNMSRP EHRRIPVKHQ KALWFSGLRG
     AMAFALALQS VHELPEGHGK TIFTTTTAIV VLTVLLIGGS TGTMLESLDV VGDENTSREN
     YEDNNGYMPP SYEEGTSSGG GLRMKLKQFH KSTTSFTALD KNYLTPFFTS QTDDDNDDDF
     SQQPQNRRLA FYDQ
//