ID   A0A1D6IVR6_MAIZE        Unreviewed;      1802 AA.
AC   A0A1D6IVR6;
DT   30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2016, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   RecName: Full=HECT-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012485};
DE            EC=2.3.2.26 {ECO:0000256|ARBA:ARBA00012485};
GN   ORFNames=ZEAMMB73_Zm00001d023795 {ECO:0000313|EMBL:AQK40074.1};
OS   Zea mays (Maize).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC   Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX   NCBI_TaxID=4577 {ECO:0000313|EMBL:AQK40074.1};
RN   [1] {ECO:0000313|EMBL:AQK40074.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Seedling {ECO:0000313|EMBL:AQK40074.1};
RG   Maize Genome Sequencing Project;
RA   Ware D.;
RT   "Update maize B73 reference genome by single molecule sequencing
RT   technologies.";
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine +
CC         [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC         cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.;
CC         EC=2.3.2.26; Evidence={ECO:0000256|ARBA:ARBA00000885};
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DR   EMBL; CM000786; AQK40074.1; -; Genomic_DNA.
DR   ExpressionAtlas; A0A1D6IVR6; baseline and differential.
DR   GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR   CDD; cd00078; HECTc; 1.
DR   Gene3D; 6.10.250.1630; -; 1.
DR   Gene3D; 3.30.2160.10; Hect, E3 ligase catalytic domain; 1.
DR   Gene3D; 3.30.2410.10; Hect, E3 ligase catalytic domain; 1.
DR   Gene3D; 3.90.1750.10; Hect, E3 ligase catalytic domains; 1.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR010309; E3_Ub_ligase_DUF908.
DR   InterPro; IPR000569; HECT_dom.
DR   InterPro; IPR035983; Hect_E3_ubiquitin_ligase.
DR   InterPro; IPR025527; HUWE1/Rev1_UBM.
DR   PANTHER; PTHR11254; HECT DOMAIN UBIQUITIN-PROTEIN LIGASE; 1.
DR   PANTHER; PTHR11254:SF398; HECT-TYPE E3 UBIQUITIN TRANSFERASE; 1.
DR   Pfam; PF06012; DUF908; 2.
DR   Pfam; PF00632; HECT; 1.
DR   Pfam; PF14377; UBM; 3.
DR   SMART; SM00119; HECTc; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   SUPFAM; SSF56204; Hect, E3 ligase catalytic domain; 1.
DR   PROSITE; PS50237; HECT; 1.
PE   4: Predicted;
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT   DOMAIN          1461..1802
FT                   /note="HECT"
FT                   /evidence="ECO:0000259|PROSITE:PS50237"
SQ   SEQUENCE   1802 AA;  199738 MW;  DDBDFA5F73ECB856 CRC64;
     MTEADPMPKN AILKILRVMQ IILENCQNRS SFTGLAHLKL LLASSDPEIV VAALETLVAL
     VKINPSKLHM NGKLISCGPI NTHLLSLAQG WGSKEEGLGI YSCVVANEGN HQGGLSLFPV
     DLENKYGGTQ HRLGSTLHFE YNLGPAQYPG QTSDKGKSSN LCVIHIPDMH LQKEDDLSIL
     KQCVDKFNVP PEHRFALLTR IRYARAFNSA RTCRIYSRIS LLSFIVLVQS SDAHDELTYF
     FTNEPEYINE LIRLVRSEDS VPGSIRALAM LALGAQLAAY ASSHERARIL SGSSIISAGG
     NRMVLLSVLQ KAISSLNSLN EDGEDDEDED EENNNLEEDD AHRMSHPDTD QEDREMDEEE
     FDEDLLEEDD EDEDEEGVIL RLEEGINGIN VLDHVEVFGG SNNLSGDTLR VMPLDIFGTR
     RQGRSTSIYN LLGRASDHGV LDHPLLEEPS STTNFSDQGH PENLVEMAFS DRNHESSSSR
     LDAIFRSLRS GRNGHRFNMW LDDGPQRNGS AAPAVPEGIE ELLISHLRRP TPQPDGQRTP
     VGGAQENDQP NHGSDAEARE VAPAQQNENS ESTLNPLDLS ECAGPAPPDS DALQRDVSNA
     SELATEMQYE RSDAITRDVE AVSQASSGSG ATLGESLRSL EVEIGSVEGH DDGDRHGTSG
     TSERLPLGDI QAAARSRRPS GNAVPVSSRD MSLESVSEVP QNPDQEPDQN ASEGNQEPTR
     AAGADSIDPT FLEALPEDLR AEVLSSRQNQ VTQTSNDQPQ DDGDIDPEFL AALPPDIREE
     VLAQQRTQRM QQQSQELEGQ PVEMDAVSII ATFPSEIREE VLLTSPDTLL ATLTPALVAE
     ANMLRERFAH RYHSSSLFGM NSRNRRGESS RRDIMAAGLD RNTGDPSRST SKPIETEGAP
     LVDEDGLKAL IRLLRVVQPL YKGQLQKLLV NLCTHRGSRQ ALVQILVDML MLDLQGFSKK
     SIDAPEPPFR LYGCHANIAY SRPQSSDGLP PLVSRRVLET LTNLARSHPN VAKLLLFLEF
     PCPSRCFPEA HDHRHGKAVL LDDGEEQKTF ALVLLLNLLD QPLYMRSVAH LEQLLNLLDV
     VMHNAENEIK QAKLEASSEK PSAPDNAVQD GKNNSDISVS YGSELNPEDG SKAPAVDNRS
     NLQAVLRSLP QPELRLLCSL LAHDGLSDSA YLLVGEVLKK IVALAPFFCC HFINELARSM
     QNLTLRAMKE LHLYENSEKA LLSSSSANGT AVLRVVQALS SLVNTLQERK DPEQPAEKDH
     SDAVSQISEI NTALDSLWLE LSNCISKIES SSEYASNLSP ASASAAMLTT GVAPPLPAGT
     QNLLPYIESF FVTCEKLRPG QPDAVQDAST SDMEDASTSS GGQRSSACQA SLDEKQNAFV
     KFSEKHRRLL NAFIRQNSGL LEKSFSLMLK IPRLIDFDNK RAYFRSKIKH QYDHHHHSPV
     RISVRRPYIL EDSYNQLRMR SPQDLKGRLT VQFQGEEGID AGGLTREWYQ SISRVIVDKS
     ALLFTTVGND LTFQPNPNSV YQTEHLSYFK FVGRVVGKAL FDGQLLDAHF TRSFYKHILG
     VKVTYHDIEA IDPSYYKNLK WMLENDISDV LDLTFSMDAD EEKLILYEKA EVTDCELIPG
     GRNIRVTEEN KHEYVDRVAE HRLTTAIRPQ INAFLEGFNE LIPRELISIF NDKELELLIS
     GLPDIDLDDL KTNTEYSGYS IASPVVQWFW EIVQGFSKED KARFLQFVTG TSKVPLEGFS
     ELQGISGPQR FQIHKAYGST NHLPSAHTCF NQLDLPEYTS KEQLQERLLL AIHEANEGFG
     FG
//