ID   A0A1D6JAX7_MAIZE        Unreviewed;      1626 AA.
AC   A0A1D6JAX7;
DT   30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2016, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=ATP-dependent DNA helicase {ECO:0000256|RuleBase:RU363044};
DE            EC=3.6.4.12 {ECO:0000256|RuleBase:RU363044};
GN   ORFNames=ZEAMMB73_Zm00001d025929 {ECO:0000313|EMBL:AQK45050.1};
OS   Zea mays (Maize).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC   Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX   NCBI_TaxID=4577 {ECO:0000313|EMBL:AQK45050.1};
RN   [1] {ECO:0000313|EMBL:AQK45050.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Seedling {ECO:0000313|EMBL:AQK45050.1};
RG   Maize Genome Sequencing Project;
RA   Ware D.;
RT   "Update maize B73 reference genome by single molecule sequencing
RT   technologies.";
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC         Evidence={ECO:0000256|RuleBase:RU363044};
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|RuleBase:RU363044};
CC   -!- SIMILARITY: Belongs to the helicase family.
CC       {ECO:0000256|RuleBase:RU363044}.
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DR   EMBL; CM000786; AQK45050.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1D6JAX7; -.
DR   InParanoid; A0A1D6JAX7; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0000723; P:telomere maintenance; IEA:InterPro.
DR   CDD; cd18809; SF1_C_RecD; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR010285; DNA_helicase_pif1-like.
DR   InterPro; IPR025476; Helitron_helicase-like.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR049163; Pif1-like_2B_dom.
DR   PANTHER; PTHR45786; DNA BINDING PROTEIN-LIKE; 1.
DR   PANTHER; PTHR45786:SF74; HELITRON_LIKE_N DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF14214; Helitron_like_N; 1.
DR   Pfam; PF05970; PIF1; 1.
DR   Pfam; PF21530; Pif1_2B_dom; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|RuleBase:RU363044};
KW   DNA damage {ECO:0000256|RuleBase:RU363044};
KW   DNA recombination {ECO:0000256|RuleBase:RU363044};
KW   DNA repair {ECO:0000256|RuleBase:RU363044};
KW   Helicase {ECO:0000256|RuleBase:RU363044};
KW   Hydrolase {ECO:0000256|RuleBase:RU363044};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU363044}.
FT   DOMAIN          607..788
FT                   /note="Helitron helicase-like"
FT                   /evidence="ECO:0000259|Pfam:PF14214"
FT   DOMAIN          1449..1495
FT                   /note="DNA helicase Pif1-like 2B"
FT                   /evidence="ECO:0000259|Pfam:PF21530"
SQ   SEQUENCE   1626 AA;  187051 MW;  AF0469486C61C68C CRC64;
     MSDEKKNELK RRRQSSKNEN VVHHERSKAQ TGHQHDSNPS SEVLDARERK RIREQIRFAT
     LTREQRALRN TTPCQKSARE NYSRRQQAML AQDSIAIENP KFTPELVWSS ADSQPPTVSL
     SSSKDMVISE LSATPFVYAS LQTKDVDMDK MTQSPRRQRH EHHVSSGERQ SLISRQNQKF
     QSAIRRNFAT ATRDHGMEGG EHNEIDHAIA SEIENNKSTS PCPVTAPHSD IMTEGADWLK
     PCESIDADEG VLFVENHDED VLFEDDDEED GYLFAGQDGE SIEDIEIDET QDAFTVNPDV
     PDLYDKVYSN IPEETHLLST VADCGYCKAK KFQYEPPGFC CRNGQIDLAP FETPPQLRRL
     WECSDADARH FRDNIRFFNG HFSFTSLYCC LDSMTTNMDC GIYTFRAHGM MYHNVRSFGR
     EVGAEHKHLE LYFYDDDPSL EHRYRKCRQE QFEKDKAVIK QLVEILKGNP YSEHLRSMGN
     VDNIEDYHIA LNLDQTLNQK LYNVPITSEV AAVWIEGSER RGQFSNSVML HGKDRSSHGI
     RSYHGCYDAL SYPLFFPKGE LGWHANIPKS NVSMDEVDAY RDQHRRSDAN NDDTERPSHL
     CVSVRDYYCY RFQIRPSIFN PILHGKRLFQ QFAVDTYIKI ESSRLDFIRK NQDRLRADLY
     KGLVDSLHEG ENRADKIGKR TVLSTSFIGG PRDMRRRYMD AMALVRKFGK PDIFLTMTCN
     PNWDEITREL LPMQSPQDRP DLVVRIFRAK LEELKKRLTK HHILGKIRAY VYVVEFQKRG
     LPHVHFLLIM QRKYKLTCPD QYDHLISAEI PDKKKYPELY KMVIKHMMHG PCGLLNPKCP
     CTKGRASCKN HYPRAFSNAT SQGKDSYPIY RRRDDGRKET VRGCELDNRW VVPYNPYLLR
     LFNCHINVEA CGSIKAVKYL FKYIYKGHDR ASVAVTDANK ADGDVDEIKQ YRDARWVTPP
     EALWRIFSFD LSQNSPPVMQ LQLHLENMHM VSFHERAKVN HVVQRPGADR SMLTAYFEAN
     RLHEEARGIL YRDFPEWYTL QQGKVWQRRK RNTGGQVGRI VSAHPAEGER FYLRLLLNHV
     TGATSYADLR TVDGETLPSF REAAQRRGLL EADDTIDECL NEAAIYQMPS ALRRLFATIL
     VYCEPNDVAE LWQRHLDSMS EDYHRSTQSK THVQQMVLID IRNILQSMGK DIKTFPLPAI
     IDKYDDSHGT DREIYEEESI EPTAEDVAMK ETLNEEQSFT KQSGTAKLLQ KASLIIWDEA
     SMTKRQAIEA LDNSMRDIMG RPGLPFGGRT VVFGGDFRQV LPVVRKGSRA QIVAASLRSS
     YLWESMCHLK LVQNMRAQSD PWFAEYLLRV GGGTEEANND GDVRLPDEVC VPYTGNDCDL
     DRLIDDIYPN LNANMSNTSY ITSRAILSTR NDWVDMINMR MIDRFQGEQM MYHSFDTAVD
     DPNNYYPSEF LNTLTPNGLP PHVLKLKVGC PIMLLRNIDP ANGLCNGTRL VVRGFQKNSI
     DAEIVLGQHA GMRIFLPRIP LCPSDDEMFP FQFKRKQFPI RLSFAMTVNK AQGQTIPNVG
     VYLPEPVFSH GQLYVALSRA TARSKVKILA IPVHDEKKKK KGVERNSAIN GATYTKNIVY
     KEVLTP
//