ID A0A1D6JG14_MAIZE Unreviewed; 456 AA.
AC A0A1D6JG14;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Cysteine protease 1 {ECO:0000313|EMBL:AQK46673.1};
GN ORFNames=ZEAMMB73_Zm00001d026458 {ECO:0000313|EMBL:AQK46673.1};
OS Zea mays (Maize).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX NCBI_TaxID=4577 {ECO:0000313|EMBL:AQK46673.1};
RN [1] {ECO:0000313|EMBL:AQK46673.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Seedling {ECO:0000313|EMBL:AQK46673.1};
RG Maize Genome Sequencing Project;
RA Ware D.;
RT "Update maize B73 reference genome by single molecule sequencing
RT technologies.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase C1 family.
CC {ECO:0000256|ARBA:ARBA00008455}.
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DR EMBL; CM000786; AQK46673.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1D6JG14; -.
DR ExpressionAtlas; A0A1D6JG14; baseline and differential.
DR GO; GO:0008234; F:cysteine-type peptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd02248; Peptidase_C1A; 1.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR Gene3D; 2.10.25.160; Granulin; 1.
DR InterPro; IPR000118; Granulin.
DR InterPro; IPR037277; Granulin_sf.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR025661; Pept_asp_AS.
DR InterPro; IPR000169; Pept_cys_AS.
DR InterPro; IPR025660; Pept_his_AS.
DR InterPro; IPR013128; Peptidase_C1A.
DR InterPro; IPR000668; Peptidase_C1A_C.
DR InterPro; IPR039417; Peptidase_C1A_papain-like.
DR InterPro; IPR013201; Prot_inhib_I29.
DR PANTHER; PTHR12411; CYSTEINE PROTEASE FAMILY C1-RELATED; 1.
DR PANTHER; PTHR12411:SF937; CYSTEINE PROTEINASE RD21A; 1.
DR Pfam; PF00396; Granulin; 1.
DR Pfam; PF08246; Inhibitor_I29; 1.
DR Pfam; PF00112; Peptidase_C1; 1.
DR PRINTS; PR00705; PAPAIN.
DR SMART; SM00277; GRAN; 1.
DR SMART; SM00848; Inhibitor_I29; 1.
DR SMART; SM00645; Pept_C1; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR SUPFAM; SSF57277; Granulin repeat; 1.
DR PROSITE; PS00640; THIOL_PROTEASE_ASN; 1.
DR PROSITE; PS00139; THIOL_PROTEASE_CYS; 1.
DR PROSITE; PS00639; THIOL_PROTEASE_HIS; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022807};
KW Protease {ECO:0000313|EMBL:AQK46673.1};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Thiol protease {ECO:0000256|ARBA:ARBA00022807}.
FT DOMAIN 46..106
FT /note="Cathepsin propeptide inhibitor"
FT /evidence="ECO:0000259|SMART:SM00848"
FT DOMAIN 135..350
FT /note="Peptidase C1A papain C-terminal"
FT /evidence="ECO:0000259|SMART:SM00645"
FT DOMAIN 360..417
FT /note="Granulins"
FT /evidence="ECO:0000259|SMART:SM00277"
SQ SEQUENCE 456 AA; 49424 MW; 9D0333D9E60A7B00 CRC64;
MGASTTPLAS AAALLLLLLA PLAAAADSMS IVSYGERSEE EARRMYAEWM AAHGRTYNAV
GEEERRFEVF RDNLRYVDAH NAAADAGVHS FRLGLNRFAD LTNDEYRATY LGVRSRPQRE
RRLGDRYLAG DNEDLPESVD WRAKGAVAEV KDQGSCGSCW AFSTIAAVEG INQIVTGDMI
SLSEQELVDC DTSYNQGCNG GLMDYAFEFI INNGGIDTEE DYPYKGTDGR CDVNRKNAKV
VTIDSYEDVP ANSEKSLQKA VANQPISVAI EAGGRAFQLY NSGIFTGTCG TALDHGVTAV
GYGTENGKDY WIVKNSWGSS WGESGYVRME RNIKASSGKC GIAVEPSPTP PSPTPPPTVC
DNYYSCPDST TCCCIYEYGK YCFAWGCCPL EGATCCDDHY SCCPHDYPVC NVKQGTCLMG
KDSPLSLSVK ATKRTLAKPH WAFPGNTAAD GMKSSA
//
