ID   A0A1D6K1G5_MAIZE        Unreviewed;      1397 AA.
AC   A0A1D6K1G5;
DT   30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2016, sequence version 1.
DT   22-FEB-2023, entry version 30.
DE   SubName: Full=Guanine nucleotide exchange factor SPIKE 1 {ECO:0000313|EMBL:ONL97627.1};
GN   ORFNames=ZEAMMB73_Zm00001d029004 {ECO:0000313|EMBL:ONL97627.1};
OS   Zea mays (Maize).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC   Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX   NCBI_TaxID=4577 {ECO:0000313|EMBL:ONL97627.1};
RN   [1] {ECO:0000313|EMBL:ONL97627.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   TISSUE=Seedling {ECO:0000313|EMBL:ONL97627.1};
RG   Maize Genome Sequencing Project;
RA   Ware D.;
RT   "Update maize B73 reference genome by single molecule sequencing
RT   technologies.";
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the DOCK family. {ECO:0000256|PROSITE-
CC       ProRule:PRU00983}.
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DR   EMBL; CM007647; ONL97579.1; -; Genomic_DNA.
DR   EMBL; CM007647; ONL97627.1; -; Genomic_DNA.
DR   EMBL; CM007647; ONL97635.1; -; Genomic_DNA.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   CDD; cd08679; C2_DOCK180_related; 1.
DR   Gene3D; 2.60.40.150; C2 domain; 1.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR027007; C2_DOCK-type_domain.
DR   InterPro; IPR035892; C2_domain_sf.
DR   InterPro; IPR026791; DOCK.
DR   PANTHER; PTHR23317; DEDICATOR OF CYTOKINESIS DOCK; 1.
DR   PANTHER; PTHR23317:SF76; LD20667P; 1.
DR   Pfam; PF14429; DOCK-C2; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   PROSITE; PS51650; C2_DOCK; 1.
PE   3: Inferred from homology;
FT   DOMAIN          472..631
FT                   /note="C2 DOCK-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51650"
FT   REGION          93..127
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          298..321
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        106..127
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        300..321
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1397 AA;  157773 MW;  8C947F44E7F42BB6 CRC64;
     MEPAVATAGE GQRFKRIPRQ AWSGNLELGP LLNESLDHWP HLNELVQCYK ADFVKDDCKY
     GHYESVASPS FQNQIFEGPD TDIETELQLC NARHSKSEDA TEDDTPSTSG RQIYETESSG
     SSSKVHCSLS PLPAYEAAFD WENERSLIFG QRVPESIPAI SNSGLKITVK VLSLSFQAGL
     VEPFSGTICL YNRDRRERLS EDFYFHMLPT DMQVDQGSLD RRGVFSLDAP SPSVCLLIQL
     EKAATEEGGV TPSVYSRKEP VHLAEKEKQK LQVWSRIMPY KESFAWAMIP LFESNRAGGL
     SDAASPSSPL APSLSGSSSQ DSIVDPISKL ALDGKVNHYS SGSSVIVEIS NLNKVKESYI
     EDSLQDPKRK VHKPVKGVLR LEVEKLHDDH NDVDNASEGG SMANDLNDAG DINNGRSNRS
     SFDGIHSSVN SIAIAKKDAH HNGHTSNAEN VDNFQAFDFR VLTRSEPFSQ LFHCLYVYPL
     TVSLSRKRNL FVRVELRKDD SDIRKPPLEA VHPRERNTML QKWGHTQIAV GTRMASYHDE
     VKISLPALLT PQHHLVFTFF HVDLQMKLEA PKPVIIGYSV LPLSTHIQLL SDVSLPILRE
     LVPHYLQESG KERMDYLEDG KTVFRLRLRL CSSLFPINER IRDFFVEYDR HTLHTSPPWG
     SELLEAINSL KNVESTALLQ FLQPILNMLL HLIGDGGETL QVAAFRAMVN ILTRVQQESS
     DGAERNRFLI NYVDFAFDDF GDRQAPVYPG LTTVWGSLAR SKAKGYRVGP VYDDVLAMAW
     FFLELIVKSM GLEQSRLFYH NLPLGEDVPP LQLKEGVFRC IMQLFDCLLT EVHERCKKGL
     SLAKRLNSTL AFFCYDLLSI IEPRQVFELV SLYMDKFAGV CQSVLHDCKL TFLQIICDHD
     LFVEMPGRDP SDRNYLSSVL IQEIFLTLDH DDLSQRAKAA RILVVLICKH EFDARYQKSE
     DKLYIAQLYF PLIGQILDEM PVFYNLNAIE KREVLVVILQ IVRNLDDATL IKAWQQSIAR
     TRLFFKLLEE CIIHFEHNKT GDNMLLGASS RSPDVEHPAS PKYSERLSPS VNTYLSEASR
     HEIRPQGTPE NGYMWNRVSP QLSSPNQPYS LREALAQAQS SRIGSTARAL RESLHPVLRQ
     KMELWEENLS TAVSLEVLGI TEKFSVAAGA RSITTDYAKL DCVTSILMGL LSRNQSLAFW
     KAFLPVVYNI FNVHGATLMA RENDRFLKQI AFHLLRLAVF RNDSIRKRAV VGLQILVRNS
     FNYFKNTTRL RVMLTITLSE LMSDVQVTQM KFDGSLEESG EARRLRKSLE EMADVRSKDL
     LKDCGLPVTA LEAAPEGSSD NRWSWVEVKH LSKCLVQALD AGLEHALLGS VVTVDSICVM
     HTRRCNHGLK QHNVQLL
//