ID   A0A1D6K1H4_MAIZE        Unreviewed;      1068 AA.
AC   A0A1D6K1H4;
DT   30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2016, sequence version 1.
DT   22-FEB-2023, entry version 27.
DE   SubName: Full=Guanine nucleotide exchange factor SPIKE 1 {ECO:0000313|EMBL:ONL97577.1};
GN   ORFNames=ZEAMMB73_Zm00001d029004 {ECO:0000313|EMBL:ONL97577.1};
OS   Zea mays (Maize).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC   Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX   NCBI_TaxID=4577 {ECO:0000313|EMBL:ONL97577.1};
RN   [1] {ECO:0000313|EMBL:ONL97577.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   TISSUE=Seedling {ECO:0000313|EMBL:ONL97577.1};
RG   Maize Genome Sequencing Project;
RA   Ware D.;
RT   "Update maize B73 reference genome by single molecule sequencing
RT   technologies.";
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the DOCK family. {ECO:0000256|PROSITE-
CC       ProRule:PRU00984}.
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DR   EMBL; CM007647; ONL97577.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1D6K1H4; -.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   CDD; cd11684; DHR2_DOCK; 1.
DR   Gene3D; 1.20.58.740; -; 1.
DR   Gene3D; 1.25.40.410; -; 1.
DR   InterPro; IPR026791; DOCK.
DR   InterPro; IPR043161; DOCK_C_lobe_A.
DR   InterPro; IPR043162; DOCK_C_lobe_C.
DR   InterPro; IPR027357; DOCKER_dom.
DR   InterPro; IPR046769; DOCKER_Lobe_A.
DR   InterPro; IPR046770; DOCKER_Lobe_B.
DR   InterPro; IPR046773; DOCKER_Lobe_C.
DR   PANTHER; PTHR23317; DEDICATOR OF CYTOKINESIS DOCK; 1.
DR   PANTHER; PTHR23317:SF76; LD20667P; 1.
DR   Pfam; PF06920; DHR-2_Lobe_A; 1.
DR   Pfam; PF20422; DHR-2_Lobe_B; 1.
DR   Pfam; PF20421; DHR-2_Lobe_C; 1.
DR   PROSITE; PS51651; DOCKER; 1.
PE   3: Inferred from homology;
KW   Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658}.
SQ   SEQUENCE   1068 AA;  120739 MW;  74DB9F20D215DFB0 CRC64;
     MGLKEIDSLL TMELIVKSMG LEQSRLFYHN LPLGEDVPPL QLKEGVFRCI MQLFDCLLTE
     VHERCKKGLS LAKRLNSTLA FFCYDLLSII EPRQVFELVS LYMDKFAGVC QSVLHDCKLT
     FLQIICDHDL FVEMPGRDPS DRNYLSSVLI QEIFLTLDHD DLSQRAKAAR ILVVLICKHE
     FDARYQKSED KLYIAQLYFP LIGQILDEMP VFYNLNAIEK REVLVVILQI VRNLDDATLI
     KAWQQSIART RLFFKLLEEC IIHFEHNKTG DNMLLGASSR SPDVEHPASP KYSERLSPSV
     NTYLSEASRH EIRPQGTPEN GYMWNRVSPQ LSSPNQPYSL REALAQAQSS RIGSTARALR
     ESLHPVLRQK MELWEENLST AVSLEVLGIT EKFSVAAGAR SITTDYAKLD CVTSILMGLL
     SRNQSLAFWK AFLPVVYNIF NVHGATLMAR ENDRFLKQIA FHLLRLAVFR NDSIRKRAVV
     GLQILVRNSF NYFKNTTRLR VMLTITLSEL MSDVQVTQMK FDGSLEESGE ARRLRKSLEE
     MADVRSKDLL KDCGLPVTAL EAAPEGSSDN RWSWVEVKHL SKCLVQALDA GLEHALLGSV
     VTVDRYAAAE GFYKLAMAYA PVPDLHIMWL LHLCDAHQEM QSWAEAAQCA VAVAGVIMQA
     LVGRNDAVWS KEHVASLRKI CPIVNTDVSA EASAAEVEGY GASKLTVDSA VKYLQLANKL
     FTQAELYHFC ASIQELIIPV YKSRRAYGQL AKCHTSLTNI YESILEQEAS PIPFIDATYY
     RVGFYGERFG KLNKKEYVFR EPRDVRLGDI MEKLSHIYEA KIDGSHTLHI IPDSRQVNAD
     ELQPGFCYLQ ITAVDPVMED EDLGSRRERI FSLSTGTVRA RVFDRFLFDT PFTKNGKTQG
     GLEDQWKRRT VLQTEGSFPA LVNRLPVIKS ESLEFSPVEN AIGMIETRTA ALRNELEEPR
     SSEGDQLPRL QSLQRILQGS VAVQVNSGVL SVCTAFLSGE PATRLRSQEL QQLIAALLEF
     MAVCKRAIRV HFRLIGEEDQ EFHTQLVNGF QSLTAELSHY IPAILSEL
//