ID   A0A1D6KDC3_MAIZE        Unreviewed;      1566 AA.
AC   A0A1D6KDC3;
DT   30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2016, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   RecName: Full=ATP-dependent DNA helicase {ECO:0000256|RuleBase:RU363044};
DE            EC=3.6.4.12 {ECO:0000256|RuleBase:RU363044};
GN   ORFNames=ZEAMMB73_Zm00001d030646 {ECO:0000313|EMBL:ONM01236.1};
OS   Zea mays (Maize).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC   Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX   NCBI_TaxID=4577 {ECO:0000313|EMBL:ONM01236.1};
RN   [1] {ECO:0000313|EMBL:ONM01236.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   TISSUE=Seedling {ECO:0000313|EMBL:ONM01236.1};
RG   Maize Genome Sequencing Project;
RA   Ware D.;
RT   "Update maize B73 reference genome by single molecule sequencing
RT   technologies.";
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC         Evidence={ECO:0000256|RuleBase:RU363044};
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|RuleBase:RU363044};
CC   -!- SIMILARITY: Belongs to the helicase family.
CC       {ECO:0000256|RuleBase:RU363044}.
CC   -!- SIMILARITY: Belongs to the peptidase C48 family.
CC       {ECO:0000256|ARBA:ARBA00005234}.
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DR   EMBL; CM007647; ONM01236.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1D6KDC3; -.
DR   STRING; 4577.A0A1D6KDC3; -.
DR   InParanoid; A0A1D6KDC3; -.
DR   ExpressionAtlas; A0A1D6KDC3; baseline.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008234; F:cysteine-type peptidase activity; IEA:InterPro.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   GO; GO:0000723; P:telomere maintenance; IEA:InterPro.
DR   CDD; cd18809; SF1_C_RecD; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR   InterPro; IPR010285; DNA_helicase_pif1-like.
DR   InterPro; IPR025476; Helitron_helicase-like.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR038765; Papain-like_cys_pep_sf.
DR   InterPro; IPR003653; Peptidase_C48_C.
DR   InterPro; IPR049163; Pif1-like_2B_dom.
DR   PANTHER; PTHR10492:SF94; ATP-DEPENDENT DNA HELICASE; 1.
DR   PANTHER; PTHR10492; UNCHARACTERIZED; 1.
DR   Pfam; PF14214; Helitron_like_N; 1.
DR   Pfam; PF02902; Peptidase_C48; 1.
DR   Pfam; PF05970; PIF1; 1.
DR   Pfam; PF21530; Pif1_2B_dom; 1.
DR   SUPFAM; SSF54001; Cysteine proteinases; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR   PROSITE; PS50600; ULP_PROTEASE; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|RuleBase:RU363044};
KW   DNA damage {ECO:0000256|RuleBase:RU363044};
KW   DNA recombination {ECO:0000256|RuleBase:RU363044};
KW   DNA repair {ECO:0000256|RuleBase:RU363044};
KW   Helicase {ECO:0000256|RuleBase:RU363044};
KW   Hydrolase {ECO:0000256|RuleBase:RU363044};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU363044}.
FT   DOMAIN          1013..1205
FT                   /note="Ubiquitin-like protease family profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50600"
SQ   SEQUENCE   1566 AA;  180497 MW;  0EBA2947CF758C71 CRC64;
     MLDGDIRGEK VGKRTMLSTS FIGGPRDMRR RYMDAMALVR KFGKPDIFLT MTCNPNWDEI
     RRELLPGQIP QDRSDLVVRV FHAKLQELKH QLTKQDILGK VRAYVYVVEF QKRGLPHAHL
     LLIMQRKYKL TCPEQYDLLI SAEIPSNKYP ELRKMVIKHM MHGPCGSLNP NCPCTKGRKS
     CKNHYPQPFS DTTLQGKDSY PIYRRRDDDR KEKVRGCELD NRWVVPYNPY LLRLFNCHIN
     VEACGSIKAI KYLFKYIYKG HDRASVVMRD ASKADDDVDE IKQYRDARWV TPPEALWRIY
     GFELSQISPP VMQLQLHLPN MHMVAFHERQ MVERVVNRPG VDRSMLTSYF EANRLHEKAR
     GILYRDFPEW YTWQSGKGKV WQRRKRDTGG QVGRIVSAHP AERERYYLRV LLNHVTGAAS
     YVDLRTVDGV TLPTFHEAAE KRKLLESDNT LDECLTERAL FQMPSSLRRL FATILVYCEP
     SDVAVLWNML HSMGKDIKTF PLPPMIDAYD DAIGTAREVY EEESIQPTVE DVALKDSLNE
     EQRAAYDKIM SAVDTDQGGL FFVDGPGGAG KTYLYRVLLA TLRNQGKIAV ATATSGVDEA
     SMTKRQAVEA LDNSMRDIMG RPALPFGGKT IVFGGDFRQV LPVVRKGSRA QVVASSLRMS
     YLWESMSHLK LVSNMRAKND PWFAEFLLRV GGGTEETNSD GDIRLPDDVC VPYSGSDNDL
     DNLIDFAFPN LNENMSDSTY ITSRAILSTR NDWVDMINVK MIDRFQGEHM VYHSFDSAMD
     DPHNYYPPEF LNTLTPNGLP PHVLKLKIGC PVILLRNIDP ANGLCNGTRL VVRGFQRNSI
     DAEIVLGQHV GKRIFLPCIL LCPSDEEMFP FQFKRKQFPV RLSFAMTVNK AQGQTIPNVG
     VYLPEPVFSH GQLYVALSRA TARSNIKILV IPAVDGRKKS RKGFCPARME SLFVGLSHNK
     PKKSVATAIV REVLYHDWLL LDYICTQGDL ALIDFIKEIP CEPRVEVVLI DDAFVERKWM
     ECLFQPSAYL GDEVIDCYIN LIKAQKHLKC RSGGRVHIEN AFQFNFLKQD GDLEIKTEEL
     YPIKDMAHIC SAERRVLLYL DHDMVFIPIN IRETHWYLAV IHARNMEIQV LDSLGTSQDR
     KDLTDSIKGL QIQIDMISQR KELKDHRWPD LQVASWPLRE INMGYAKQTD SSSCGLFLLN
     YIEYWTGDEL SNSFTQDDMS HFRKKMAAIL LSLDLNKRRG CLLYKNEKEV DSRSPSDVEL
     LENPTDSNKR KLLHVLDDSE VVYEDEEGPI TQADLQRWFV DDWDKRAPVK VSTDGCTNDF
     LMVGLSTKDM PVTKADSIDV LCDYIMLIED DTTLERTWVR SFNPFKIEIS VKDLQNILTT
     TQDMILRCFD MAVRLLANKE SRRPKQEIIN NRKHYMDMRF WRMVGFGKLP KYHQDPTTEE
     LAKTLDCWPS MNYYITGCRY VLMPWKFNGC YALFIIDHVK KHVTFIDFTP TQDWCKHMPY
     KRFNTSYLVL QAMAMWGNDR PLKFVGDAKT LRRNFVIDLL SYEDNSCRYA IPANIQQRLI
     DIAKKD
//