ID   A0A1D6KFZ5_MAIZE        Unreviewed;       299 AA.
AC   A0A1D6KFZ5; A0A317YK28;
DT   30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2016, sequence version 1.
DT   24-JAN-2024, entry version 38.
DE   RecName: Full=RING-type E3 ubiquitin transferase (cysteine targeting) {ECO:0000256|ARBA:ARBA00034523};
DE            EC=2.3.2.36 {ECO:0000256|ARBA:ARBA00034523};
DE   AltName: Full=Peroxin-2 {ECO:0000256|ARBA:ARBA00032511};
GN   ORFNames=ZEAMMB73_Zm00001d031028 {ECO:0000313|EMBL:ONM02010.1};
OS   Zea mays (Maize).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC   Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX   NCBI_TaxID=4577 {ECO:0000313|EMBL:ONM02010.1};
RN   [1] {ECO:0000313|EMBL:ONM02010.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   TISSUE=Seedling {ECO:0000313|EMBL:ONM02010.1};
RG   Maize Genome Sequencing Project;
RA   Ware D.;
RT   "Update maize B73 reference genome by single molecule sequencing
RT   technologies.";
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine +
CC         [acceptor protein]-L-cysteine = [E2 ubiquitin-conjugating enzyme]-L-
CC         cysteine + [acceptor protein]-S-ubiquitinyl-L-cysteine.; EC=2.3.2.36;
CC         Evidence={ECO:0000256|ARBA:ARBA00034438};
CC   -!- PATHWAY: Protein modification; protein ubiquitination.
CC       {ECO:0000256|ARBA:ARBA00004906}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Peroxisome
CC       membrane {ECO:0000256|ARBA:ARBA00004585}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004585}.
CC   -!- SIMILARITY: Belongs to the pex2/pex10/pex12 family.
CC       {ECO:0000256|ARBA:ARBA00008704}.
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DR   EMBL; CM007647; ONM02010.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1D6KFZ5; -.
DR   ExpressionAtlas; A0A1D6KFZ5; baseline and differential.
DR   GO; GO:0005829; C:cytosol; IEA:EnsemblPlants.
DR   GO; GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:EnsemblPlants.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006635; P:fatty acid beta-oxidation; IEA:EnsemblPlants.
DR   GO; GO:0009640; P:photomorphogenesis; IEA:EnsemblPlants.
DR   GO; GO:0016558; P:protein import into peroxisome matrix; IEA:EnsemblPlants.
DR   GO; GO:0006513; P:protein monoubiquitination; IEA:EnsemblPlants.
DR   CDD; cd16526; RING-HC_PEX2; 1.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   InterPro; IPR025654; PEX2/10.
DR   InterPro; IPR006845; Pex_N.
DR   InterPro; IPR045859; RING-HC_PEX2.
DR   InterPro; IPR018957; Znf_C3HC4_RING-type.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   InterPro; IPR017907; Znf_RING_CS.
DR   PANTHER; PTHR48178; PEROXISOME BIOGENESIS FACTOR 2; 1.
DR   PANTHER; PTHR48178:SF1; PEROXISOME BIOGENESIS FACTOR 2; 1.
DR   Pfam; PF04757; Pex2_Pex12; 1.
DR   Pfam; PF00097; zf-C3HC4; 1.
DR   SUPFAM; SSF57850; RING/U-box; 1.
DR   PROSITE; PS00518; ZF_RING_1; 1.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Peroxisome {ECO:0000256|ARBA:ARBA00023140};
KW   Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW   Transport {ECO:0000256|ARBA:ARBA00022448};
KW   Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
SQ   SEQUENCE   299 AA;  34017 MW;  9B985008078CB2FB CRC64;
     MPQVESATAS EAPPPQDAWL VELGSRLPQW ESLRDSSKPG LLFQYEPELD AFLEFLIWRF
     SIWADKPTPG NALMNLRYRD ERAAPITGKE VRTGLEGPGL SVSQKIFYCI SFVGGQYVWS
     RLQSFSAFRR WGDSEQRPLA RRAWALMRNA EVFYRAASFF NLLLFLYGGR YKTVVERILK
     ARLVYGSPNM NRAVSFEYMN RQLVWNEFSE MLLLLLPLLN SSSVKKFLLP FSKDKSGGSS
     GDEADCPICR SSPSIPFIAL PCQHRYCYYC LRTRCSATTS YRCTRCDGAV VAIQRLGSG
//