ID   A0A1D6KYU4_MAIZE        Unreviewed;       586 AA.
AC   A0A1D6KYU4;
DT   30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2016, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   SubName: Full=CSC1-like protein RXW8 {ECO:0000313|EMBL:ONM07554.1};
GN   ORFNames=ZEAMMB73_Zm00001d033401 {ECO:0000313|EMBL:ONM07554.1};
OS   Zea mays (Maize).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC   Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX   NCBI_TaxID=4577 {ECO:0000313|EMBL:ONM07554.1};
RN   [1] {ECO:0000313|EMBL:ONM07554.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   TISSUE=Seedling {ECO:0000313|EMBL:ONM07554.1};
RG   Maize Genome Sequencing Project;
RA   Ware D.;
RT   "Update maize B73 reference genome by single molecule sequencing
RT   technologies.";
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the CSC1 (TC 1.A.17) family.
CC       {ECO:0000256|ARBA:ARBA00007779}.
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DR   EMBL; CM007647; ONM07554.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1D6KYU4; -.
DR   ExpressionAtlas; A0A1D6KYU4; baseline and differential.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005227; F:calcium-activated cation channel activity; IEA:InterPro.
DR   InterPro; IPR045122; Csc1-like.
DR   InterPro; IPR003864; CSC1/OSCA1-like_7TM.
DR   InterPro; IPR027815; CSC1/OSCA1-like_cyt.
DR   InterPro; IPR032880; Csc1/OSCA1-like_N.
DR   PANTHER; PTHR13018:SF145; CSC1-LIKE PROTEIN RXW8; 1.
DR   PANTHER; PTHR13018; PROBABLE MEMBRANE PROTEIN DUF221-RELATED; 1.
DR   Pfam; PF14703; PHM7_cyt; 1.
DR   Pfam; PF02714; RSN1_7TM; 1.
DR   Pfam; PF13967; RSN1_TM; 1.
PE   3: Inferred from homology;
KW   Calcium {ECO:0000256|ARBA:ARBA00022837};
KW   Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW   Ion transport {ECO:0000256|ARBA:ARBA00023303};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW   Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   DOMAIN          6..164
FT                   /note="CSC1/OSCA1-like N-terminal transmembrane"
FT                   /evidence="ECO:0000259|Pfam:PF13967"
FT   DOMAIN          186..344
FT                   /note="CSC1/OSCA1-like cytosolic"
FT                   /evidence="ECO:0000259|Pfam:PF14703"
FT   DOMAIN          355..584
FT                   /note="CSC1/OSCA1-like 7TM region"
FT                   /evidence="ECO:0000259|Pfam:PF02714"
SQ   SEQUENCE   586 AA;  67205 MW;  DE062AF73D8CE8B4 CRC64;
     MKVGGLLTSA GINIGLCVLF LSLYSILRKQ PQNVKVYFGR RIAEEHNRLR DAFILERFVP
     SPSWIVKSLR CTEEEILATA GLDAVVFNRI LVFSIRIFSL AAILCVFGVL PLNYFGQDMH
     HVRIPSASLE TFTIGNVEER SRWLWVHCVV LYIISAVACI LLYLEYKHIA RLRLYHISRA
     TSNPSHFTIL VRGIPKSSTE SFSRTVESFF TKYHASSYLS HQVVYKVGKV QKIVSGAKKV
     YRKFRHFKGA TVDRRCRPIR FQCCFCGASS NSFQLLPSDY EQESEKSDVN ESSSSLPDEE
     CGAAFVFFKT RYAALVVAKI LQTSNPMRWV TTLAPEPDDI YWSNLWLPYK QLWIRHIVTL
     MCSIVFMVVF LIPVTFIQGL TQLEQLQQRL PFLRGILKKK YMTQLITGYL PSVILQIFLY
     TVPPTMMFFS TLEGPISHSE RKKSACCKVL YFTIWNVFFV NVLSGSAISQ LNALSSPKDI
     PMQLAKAVPV QATFFTTYVL TSGWASLSSE LMQLFGLTWN FLRRYLLRIK EDSDFLYSFP
     YHTEMPKVLL FGLLGFTCSV LAPLILPFLL LYFFLGYVVY RNQVRV
//