ID   A0A1D6L6I1_MAIZE        Unreviewed;      1843 AA.
AC   A0A1D6L6I1;
DT   30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 2.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=ATP-dependent DNA helicase {ECO:0000256|RuleBase:RU363044};
DE            EC=3.6.4.12 {ECO:0000256|RuleBase:RU363044};
GN   ORFNames=ZEAMMB73_Zm00001d034274 {ECO:0000313|EMBL:ONM09911.1};
OS   Zea mays (Maize).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC   Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX   NCBI_TaxID=4577 {ECO:0000313|EMBL:ONM09911.1};
RN   [1] {ECO:0000313|EMBL:ONM09911.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   TISSUE=Seedling {ECO:0000313|EMBL:ONM09911.1};
RG   Maize Genome Sequencing Project;
RA   Ware D.;
RT   "Update maize B73 reference genome by single molecule sequencing
RT   technologies.";
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC         Evidence={ECO:0000256|RuleBase:RU363044};
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|RuleBase:RU363044};
CC   -!- SIMILARITY: Belongs to the helicase family.
CC       {ECO:0000256|RuleBase:RU363044}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CM007647; ONM09911.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1D6L6I1; -.
DR   SMR; A0A1D6L6I1; -.
DR   InParanoid; A0A1D6L6I1; -.
DR   ExpressionAtlas; A0A1D6L6I1; baseline and differential.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0000723; P:telomere maintenance; IEA:InterPro.
DR   CDD; cd18809; SF1_C_RecD; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR010285; DNA_helicase_pif1-like.
DR   InterPro; IPR025476; Helitron_helicase-like.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR049163; Pif1-like_2B_dom.
DR   PANTHER; PTHR45786; DNA BINDING PROTEIN-LIKE; 1.
DR   PANTHER; PTHR45786:SF74; HELITRON_LIKE_N DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF14214; Helitron_like_N; 1.
DR   Pfam; PF05970; PIF1; 1.
DR   Pfam; PF21530; Pif1_2B_dom; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|RuleBase:RU363044};
KW   DNA damage {ECO:0000256|RuleBase:RU363044};
KW   DNA recombination {ECO:0000256|RuleBase:RU363044};
KW   DNA repair {ECO:0000256|RuleBase:RU363044};
KW   Helicase {ECO:0000256|RuleBase:RU363044};
KW   Hydrolase {ECO:0000256|RuleBase:RU363044};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU363044}.
FT   DOMAIN          742..923
FT                   /note="Helitron helicase-like"
FT                   /evidence="ECO:0000259|Pfam:PF14214"
FT   DOMAIN          1666..1712
FT                   /note="DNA helicase Pif1-like 2B"
FT                   /evidence="ECO:0000259|Pfam:PF21530"
SQ   SEQUENCE   1843 AA;  211109 MW;  4611861F162EA0F4 CRC64;
     MDPFNNNDVR PPLRELSSNT LEGGRTDARQ CKRERERARY AAMSAEKKNE LKNRRQSRKK
     ENVVHHEYSK DDCPDVAIGD GSIIDCTIPC GITLGGCDDA RQCKRERERA RYATMSDEKK
     NELKRRRQSS KNENVVHHER SKFVDCSIPA HKENNNHQSI DTLAQTGHQH DSNPSSEVLD
     ARERKRIREQ IRFATLTREQ RALRNTTPCQ KSARENYSRR QQAMLAQDSI AIENPKFTPE
     LVWSSADSQP PTVSLSSSKD MVISELSATP FVYASLQTKD VDMDKMIQSP RRQRHEHHVS
     SGERQSLISR QNQKFQSAIR RNFATATRDH GMEGGEHNEI DHAIASEIEN NKSTSPCPVT
     APHSDIMTEG ADWLKPCESI DADEGVLFVE NHDEDVLFED DDEEDGYLFA GQDGESIEDI
     EIDETQDAFT VNPDVPDLYD KVYSNIPEET HLLSTVADCD YCKAKKFQYE PPGFCCRNGQ
     IDLAPFETPP QLRRLWECSD ADARHFRDNI RFFNGHFSFT SLYCCLDSMT TNMDCGIYTF
     RAHGMMYHNV RSFGREVGAE HKHLELYFYD DDPSLEHRYR KCRQEQFEKD KAVIKQLVEI
     LKGNPYSEHL RSMGNIDNIE DYHIALNLDQ TLNQKLYNVP ITSEVAAVWI EGSERRGQFS
     NSVMLHGKDR SSHGIRSYHG CYDALSYPLF FPKGELGWHA NIPKSNVSMD EVDAYRDQHR
     RSDANNDDTE RPSHLCVSVR DYYCYRFQIR PSIFNPILHG KRLFQQFAVD TYIKIESSRL
     DFIRKNQDRL RADLYKGLVD SLHEGENRAD KIGKRTVLST SFIGGPRDMR RRYMDAMALV
     RKFGKPDIFL TMTCNPNWDE ITRELLPMQS PQDRPDLVVR IFRAKLEELK KRLTKHHILG
     KIRAYVYVVE FQKRGLPHVH FLLIMQRKYK LTCPDQYDHL ISAEIPDKKK YPELYKMVIK
     HMMHGPCGLL NPKCPCTKGR ASCKNHYPRA FSNATSQGKD SYPIYRRRDD GRKETVRGCE
     LDNRWVVPYN PYLLRLFNCH INVEACGSIK AVKYLFKYIY KGHDRASVAV TDANKADGDV
     DEIKQYRDAR WVTPTEALWR IFSFDLSQNS PPVMQLQLHL ENMHMVSFHE RAKVNHVVQR
     PGADRSMLTA YFEANRLHEE ARGILYRDFP EWYTLQQGKV WQRRKRNTGG QVGRIVSAHP
     AEGERFYLRL LLNHVTGATS YADLRTVDGD TLPSFREAAQ RRGLLEADDT IDECLNEAAI
     YQMPSALRRL FATILVYCEP NDVAELWQRH LDSMSEDYHR STQSKTHVQQ MVLIDIRNIL
     QSMGKDIKTF PLPAIIDKYD DSHGTDREIY EEESIEPTAE DVAMKETLNE EQRFAYDKIL
     SVVDTNNGGV FFVDGPGGTG KTYLYKALLA ALRSQDKIAV ATATSGVASS ILPGGRTAHS
     RFKIPLTIDD GAVCSFTKQS GTAKLLQKAS LIIWDEASMT KRQAIEALDN SMRDIMGRPG
     LPFGGRTVVF GGDFRQVLPV VRKGSRAQIV AASLRSSYLW ESMCHLKLVQ NMRAQSDPWF
     AEYLLRVGGG TEEANNDGDV RLPDEVCVPY TGNDRDLDRL IDDIYPNLNE NMSNTSYITS
     RAILSTRNDW VDMINMRMID RFQGEQMMYH SFDTAVDDPN NYYPSEFLNT LTPNGLPPHV
     LKLKVGCPIM LLRNIDPANG LCNGTRLVVR GFQKNSIDAE IVLGQHAGMR IFLPRIPLCP
     SDDEMFPFQF KRKQFPIRLS FAMTVNKAQG QTIPNVGVYL PEPVFSHGQL YVALSRATAR
     SKVKILAIPV HDEKKKKKGV ERNSAINGAT YTKNIVYKEV LTP
//