ID A0A1D6LA97_MAIZE Unreviewed; 577 AA.
AC A0A1D6LA97;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE RecName: Full=anthranilate synthase {ECO:0000256|ARBA:ARBA00012266};
DE EC=4.1.3.27 {ECO:0000256|ARBA:ARBA00012266};
GN ORFNames=ZEAMMB73_Zm00001d034713 {ECO:0000313|EMBL:ONM11052.1};
OS Zea mays (Maize).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX NCBI_TaxID=4577 {ECO:0000313|EMBL:ONM11052.1};
RN [1] {ECO:0000313|EMBL:ONM11052.1, ECO:0000313|Proteomes:UP000007305}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. B73 {ECO:0000313|EnsemblPlants:Zm00001eb063220_P002,
RC ECO:0000313|Proteomes:UP000007305};
RC TISSUE=Seedling {ECO:0000313|EMBL:ONM11052.1};
RG Maize Genome Sequencing Project;
RA Ware D.;
RT "Update maize B73 reference genome by single molecule sequencing
RT technologies.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblPlants:Zm00001eb063220_P002}
RP IDENTIFICATION.
RC STRAIN=cv. B73 {ECO:0000313|EnsemblPlants:Zm00001eb063220_P002};
RG EnsemblPlants;
RL Submitted (MAY-2021) to UniProtKB.
CC -!- PATHWAY: Amino-acid biosynthesis; L-tryptophan biosynthesis; L-
CC tryptophan from chorismate: step 1/5. {ECO:0000256|ARBA:ARBA00004873}.
CC -!- SUBUNIT: Heterotetramer consisting of two non-identical subunits: a
CC beta subunit and a large alpha subunit.
CC {ECO:0000256|ARBA:ARBA00011653}.
CC -!- SIMILARITY: Belongs to the anthranilate synthase component I family.
CC {ECO:0000256|ARBA:ARBA00009562}.
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DR EMBL; CM007647; ONM11052.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1D6LA97; -.
DR EnsemblPlants; Zm00001eb063220_T002; Zm00001eb063220_P002; Zm00001eb063220.
DR Gramene; Zm00001eb063220_T002; Zm00001eb063220_P002; Zm00001eb063220.
DR eggNOG; KOG1223; Eukaryota.
DR UniPathway; UPA00035; UER00040.
DR Proteomes; UP000007305; Chromosome 1.
DR ExpressionAtlas; A0A1D6LA97; baseline and differential.
DR GO; GO:0004049; F:anthranilate synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0000162; P:tryptophan biosynthetic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.60.120.10; Anthranilate synthase; 1.
DR InterPro; IPR005801; ADC_synthase.
DR InterPro; IPR019999; Anth_synth_I-like.
DR InterPro; IPR006805; Anth_synth_I_N.
DR InterPro; IPR005256; Anth_synth_I_PabB.
DR InterPro; IPR015890; Chorismate_C.
DR NCBIfam; TIGR00564; trpE_most; 1.
DR PANTHER; PTHR11236; AMINOBENZOATE/ANTHRANILATE SYNTHASE; 1.
DR PANTHER; PTHR11236:SF9; ANTHRANILATE SYNTHASE COMPONENT 1; 1.
DR Pfam; PF04715; Anth_synt_I_N; 1.
DR Pfam; PF00425; Chorismate_bind; 1.
DR PRINTS; PR00095; ANTSNTHASEI.
DR SUPFAM; SSF56322; ADC synthase; 1.
PE 1: Evidence at protein level;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00022605};
KW Aromatic amino acid biosynthesis {ECO:0000256|ARBA:ARBA00023141};
KW Lyase {ECO:0000256|ARBA:ARBA00023239};
KW Proteomics identification {ECO:0007829|PeptideAtlas:A0A1D6LA97};
KW Reference proteome {ECO:0000313|Proteomes:UP000007305};
KW Tryptophan biosynthesis {ECO:0000256|ARBA:ARBA00022822}.
FT DOMAIN 73..226
FT /note="Anthranilate synthase component I N-terminal"
FT /evidence="ECO:0000259|Pfam:PF04715"
FT DOMAIN 288..559
FT /note="Chorismate-utilising enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00425"
SQ SEQUENCE 577 AA; 64488 MW; 48C3103A2FC0E1E6 CRC64;
MATASLALSL RLAPSSRPLS LRRRGAAGVT CRATTATFHQ LDAVAVREEE SRFRTAAAEG
RNLLPLTRCI FSDHLTPVLA YRCLVKEDER DAPSFLFESV EQGSEGTNVG RYSVVGAQPS
MEVVAKANHV TVMDHEMKSR REHFVPDPMR IPRTIMEQWN PQIADSLPDA FCGGWVGFFS
YDTVRYVETK KLPFSKAPHD DRNLPDIHLG LYSDVIVFDH VEKKTHVIHW VRTDCYRSVD
EAYEDGRNRL EALLSRLHCL NVPTLSSGSI KLNVENFGPV MQKSTMSSEE YKNIVVQAKE
HILAGDIFQV VLSQRFERRT FADPFEIYRA LRIVNPSPYM AYLQARGCIL VASSPEILTR
VQKRTIINRP LAGTIRRGKT KAEDKTLEQL LLSDEKQCAE HIMLVDLGRN DVGKVSKPGS
VKVEKLMNIE RYSHVMHISS TVTGELRDDL TCWDALRAAL PVGTVSGAPK VRAMELIDQL
EVSMRGPYSG GFGGISFRGD MDIALALRTI VFPTASRFDT MYSYTDSKSR QEWVAHLQAG
AGIVADSKPD DEHQECINKA AGVARAIDLA ESTFLEE
//
