ID   A0A1D6LGM2_MAIZE        Unreviewed;       877 AA.
AC   A0A1D6LGM2;
DT   30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2016, sequence version 1.
DT   27-MAR-2024, entry version 43.
DE   SubName: Full=E3 SUMO-protein ligase SIZ1 {ECO:0000313|EMBL:AQK79088.1};
GN   ORFNames=ZEAMMB73_Zm00001d035487 {ECO:0000313|EMBL:AQK79088.1};
OS   Zea mays (Maize).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC   Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX   NCBI_TaxID=4577 {ECO:0000313|EMBL:AQK79088.1};
RN   [1] {ECO:0000313|EMBL:AQK79088.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Seedling {ECO:0000313|EMBL:AQK79088.1};
RG   Maize Genome Sequencing Project;
RA   Ware D.;
RT   "Update maize B73 reference genome by single molecule sequencing
RT   technologies.";
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- PATHWAY: Protein modification; protein sumoylation.
CC       {ECO:0000256|ARBA:ARBA00004718}.
CC   -!- SIMILARITY: Belongs to the PIAS family.
CC       {ECO:0000256|ARBA:ARBA00005383}.
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DR   EMBL; CM000782; AQK79088.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1D6LGM2; -.
DR   UniPathway; UPA00886; -.
DR   ExpressionAtlas; A0A1D6LGM2; baseline and differential.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0019789; F:SUMO transferase activity; IEA:UniProt.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016925; P:protein sumoylation; IEA:UniProtKB-UniPathway.
DR   CDD; cd15570; PHD_Bye1p_SIZ1_like; 1.
DR   CDD; cd16792; SP-RING_Siz-like; 1.
DR   Gene3D; 1.10.720.30; SAP domain; 1.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR   InterPro; IPR003034; SAP_dom.
DR   InterPro; IPR036361; SAP_dom_sf.
DR   InterPro; IPR031141; SIZ1/2_SP-RING.
DR   InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR   InterPro; IPR011011; Znf_FYVE_PHD.
DR   InterPro; IPR004181; Znf_MIZ.
DR   InterPro; IPR001965; Znf_PHD.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   PANTHER; PTHR10782:SF4; E3 SUMO-PROTEIN LIGASE SIZ1; 1.
DR   PANTHER; PTHR10782; ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF02037; SAP; 1.
DR   Pfam; PF02891; zf-MIZ; 1.
DR   SMART; SM00249; PHD; 1.
DR   SMART; SM00513; SAP; 1.
DR   SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR   SUPFAM; SSF68906; SAP domain; 1.
DR   PROSITE; PS50800; SAP; 1.
DR   PROSITE; PS01359; ZF_PHD_1; 1.
DR   PROSITE; PS51044; ZF_SP_RING; 1.
PE   3: Inferred from homology;
KW   Ligase {ECO:0000313|EMBL:AQK79088.1};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00452}.
FT   DOMAIN          12..46
FT                   /note="SAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50800"
FT   DOMAIN          351..432
FT                   /note="SP-RING-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51044"
SQ   SEQUENCE   877 AA;  97131 MW;  16D7FFE78B425F5E CRC64;
     MSDLASTSKD KLAYFRIKEL KDILNQLGLP KHGKKQDLVD RVLAELSDEQ GQRHHGWGRK
     NALTREAVAK VVDDTYRKMQ VCAPDLPSRS HSGSDFNHFR PKEEATDFYY VETKVRCLCN
     STMLNDKIIK CEDGKCQLWQ HFTCVLIPDT PTEGAGPDIP PHFYCELCRL NRADPFWVTT
     ANPLLPVKFI SSGVGNDGAS APQIVEKTFQ LSRAERETVQ RPEYDLQVWC ILVNDKVQFR
     MQWPQYAELQ VNGIPVRVMT RPGSQLLGIN GRDDGPLVTT CSREGINKIS LSRVDARTFC
     FGVRIVRRRT VPQVLSLIPK EGEGESFEDA LARVRRCLGG GGATDNADSD SDLEVVTESV
     TVNLRCPNSG SRMRIAGRFK PCVHMGCFDL ETFVELNQRS RKWQCPICLN NYSLENLMID
     PYFNRITSLL HNCSEDVNEL DVKPDGSWRV MGDAATRDLS QWHMPDGTLC DSKEDTNPGV
     ASVNEFKREG ASDEHRTLKL GIKKNPIGLW QVSSKADDMK PVVRNHIQNN TGFSTPNIVP
     MISSPTGSYR DGEDVSVNQE GGGIQFDISL NQEFDSFAHN FGQTYNTEDR PQHPHHNAAD
     VIVLSDSDEE NDPTVQPPAV YENTPTNDDS FPFVTDAAGS GYPERYQEDA SVGTSGLGLL
     RQNTGEFEIN NWQMLSYPQP EQGFQFFVTD TDVGNPFVAP HNSFTIAPED YSLGCNVGIE
     DPSAAHDVSI CRNSNDVHGS LVDNPLALTG DDPSLQIFLP SQPSTVPLQQ ELSERSDTPN
     GVHPNDWRIS LTLAAGGGGN EESTSVGGLK SQPKVSSKEA GVEPLLDAAA SALGSMNNDR
     CTGSNLNPKR IENIFSHPRQ PRSVRPRLCL SLDTDSE
//