ID   A0A1D6LII0_MAIZE        Unreviewed;       295 AA.
AC   A0A1D6LII0;
DT   30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2016, sequence version 1.
DT   27-MAR-2024, entry version 37.
DE   SubName: Full=E3 ubiquitin-protein ligase CHIP {ECO:0000313|EMBL:AQK79612.1};
GN   ORFNames=ZEAMMB73_Zm00001d035751 {ECO:0000313|EMBL:AQK79612.1};
OS   Zea mays (Maize).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC   Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX   NCBI_TaxID=4577 {ECO:0000313|EMBL:AQK79612.1};
RN   [1] {ECO:0000313|EMBL:AQK79612.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Seedling {ECO:0000313|EMBL:AQK79612.1};
RG   Maize Genome Sequencing Project;
RA   Ware D.;
RT   "Update maize B73 reference genome by single molecule sequencing
RT   technologies.";
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- PATHWAY: Protein modification; protein ubiquitination.
CC       {ECO:0000256|ARBA:ARBA00004906}.
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DR   EMBL; CM000782; AQK79612.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1D6LII0; -.
DR   SMR; A0A1D6LII0; -.
DR   IntAct; A0A1D6LII0; 23.
DR   STRING; 4577.A0A1D6LII0; -.
DR   InParanoid; A0A1D6LII0; -.
DR   OMA; PSIPAYY; -.
DR   UniPathway; UPA00143; -.
DR   ExpressionAtlas; A0A1D6LII0; baseline and differential.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0051087; F:protein-folding chaperone binding; IBA:GO_Central.
DR   GO; GO:0061630; F:ubiquitin protein ligase activity; IBA:GO_Central.
DR   GO; GO:0071218; P:cellular response to misfolded protein; IBA:GO_Central.
DR   GO; GO:0045862; P:positive regulation of proteolysis; IBA:GO_Central.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IBA:GO_Central.
DR   GO; GO:0000209; P:protein polyubiquitination; IBA:GO_Central.
DR   GO; GO:0006515; P:protein quality control for misfolded or incompletely synthesized proteins; IBA:GO_Central.
DR   CDD; cd16654; RING-Ubox_CHIP; 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   InterPro; IPR045202; CHIP_RING-Ubox.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   InterPro; IPR003613; Ubox_domain.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   PANTHER; PTHR46803; E3 UBIQUITIN-PROTEIN LIGASE CHIP; 1.
DR   PANTHER; PTHR46803:SF4; RING-TYPE E3 UBIQUITIN TRANSFERASE; 1.
DR   Pfam; PF04564; U-box; 1.
DR   SMART; SM00028; TPR; 3.
DR   SMART; SM00504; Ubox; 1.
DR   SUPFAM; SSF57850; RING/U-box; 1.
DR   SUPFAM; SSF48452; TPR-like; 1.
DR   PROSITE; PS51698; U_BOX; 1.
PE   4: Predicted;
FT   DOMAIN          217..291
FT                   /note="U-box"
FT                   /evidence="ECO:0000259|PROSITE:PS51698"
SQ   SEQUENCE   295 AA;  33791 MW;  3E0C386A62A0B881 CRC64;
     MAAGGDGVAR QAELRRIEGN ICFKKARLGA AIDCYTEAIA LCPDVAVYWI NRALCHFKRK
     EWAKVEEDSR RALALDYTLV KGHYLLGCAL LEKEESALAI KEFEKALTLL KSVDSTYEMA
     EDIWQVLAKA KYLDWEKHST ERLWRMESLN FWLLKSLNRS VSPWTCREAC ETALQEHHFL
     TGTLEEDSNR SDNEYSEQIK LLSEVFSQAT VADTPTDVPD YLCCQITFEI FRDPVITPSG
     VTYERAVLVE HLHKVGNFDP VTREPLKEHQ LVPNLAIKEA VQAYLKEHSW AHKLN
//