ID A0A1D6MNB9_MAIZE Unreviewed; 1034 AA.
AC A0A1D6MNB9;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=phosphoenolpyruvate carboxylase {ECO:0000256|ARBA:ARBA00012305};
DE EC=4.1.1.31 {ECO:0000256|ARBA:ARBA00012305};
GN Name=103649899 {ECO:0000313|EnsemblPlants:Zm00001eb126420_P003};
GN ORFNames=ZEAMMB73_Zm00001d040129 {ECO:0000313|EMBL:ONM30617.1};
OS Zea mays (Maize).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX NCBI_TaxID=4577 {ECO:0000313|EMBL:ONM30617.1};
RN [1] {ECO:0000313|EMBL:ONM30617.1, ECO:0000313|Proteomes:UP000007305}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. B73 {ECO:0000313|EnsemblPlants:Zm00001eb126420_P003,
RC ECO:0000313|Proteomes:UP000007305};
RC TISSUE=Seedling {ECO:0000313|EMBL:ONM30617.1};
RG Maize Genome Sequencing Project;
RA Ware D.;
RT "Update maize B73 reference genome by single molecule sequencing
RT technologies.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblPlants:Zm00001eb126420_P003}
RP IDENTIFICATION.
RC STRAIN=cv. B73 {ECO:0000313|EnsemblPlants:Zm00001eb126420_P003};
RG EnsemblPlants;
RL Submitted (MAY-2021) to UniProtKB.
CC -!- FUNCTION: Through the carboxylation of phosphoenolpyruvate (PEP) it
CC forms oxaloacetate, a four-carbon dicarboxylic acid source for the
CC tricarboxylic acid cycle. {ECO:0000256|ARBA:ARBA00003774}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=oxaloacetate + phosphate = hydrogencarbonate +
CC phosphoenolpyruvate; Xref=Rhea:RHEA:28370, ChEBI:CHEBI:16452,
CC ChEBI:CHEBI:17544, ChEBI:CHEBI:43474, ChEBI:CHEBI:58702; EC=4.1.1.31;
CC Evidence={ECO:0000256|ARBA:ARBA00001071};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SUBUNIT: Homotetramer. {ECO:0000256|ARBA:ARBA00011881}.
CC -!- SIMILARITY: Belongs to the PEPCase type 1 family.
CC {ECO:0000256|ARBA:ARBA00008346}.
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DR EMBL; CM007649; ONM30617.1; -; Genomic_DNA.
DR RefSeq; XP_008673805.1; XM_008675583.1.
DR AlphaFoldDB; A0A1D6MNB9; -.
DR SMR; A0A1D6MNB9; -.
DR STRING; 4577.A0A1D6MNB9; -.
DR PaxDb; 4577-GRMZM2G082780_P02; -.
DR EnsemblPlants; Zm00001eb126420_T003; Zm00001eb126420_P003; Zm00001eb126420.
DR GeneID; 103649899; -.
DR Gramene; Zm00001eb126420_T003; Zm00001eb126420_P003; Zm00001eb126420.
DR KEGG; zma:103649899; -.
DR eggNOG; ENOG502QPVS; Eukaryota.
DR InParanoid; A0A1D6MNB9; -.
DR OMA; FGWTQSR; -.
DR OrthoDB; 355614at2759; -.
DR Proteomes; UP000007305; Chromosome 3.
DR ExpressionAtlas; A0A1D6MNB9; baseline and differential.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0008964; F:phosphoenolpyruvate carboxylase activity; IBA:GO_Central.
DR GO; GO:0015977; P:carbon fixation; IEA:UniProtKB-KW.
DR GO; GO:0015979; P:photosynthesis; IEA:UniProtKB-KW.
DR GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR Gene3D; 1.20.1440.90; Phosphoenolpyruvate/pyruvate domain; 2.
DR HAMAP; MF_00595; PEPcase_type1; 1.
DR InterPro; IPR021135; PEP_COase.
DR InterPro; IPR022805; PEP_COase_bac/pln-type.
DR InterPro; IPR018129; PEP_COase_Lys_AS.
DR InterPro; IPR033129; PEPCASE_His_AS.
DR InterPro; IPR015813; Pyrv/PenolPyrv_Kinase-like_dom.
DR PANTHER; PTHR30523; PHOSPHOENOLPYRUVATE CARBOXYLASE; 1.
DR PANTHER; PTHR30523:SF6; PHOSPHOENOLPYRUVATE CARBOXYLASE; 1.
DR Pfam; PF00311; PEPcase; 2.
DR PRINTS; PR00150; PEPCARBXLASE.
DR SUPFAM; SSF51621; Phosphoenolpyruvate/pyruvate domain; 1.
DR PROSITE; PS00781; PEPCASE_1; 1.
DR PROSITE; PS00393; PEPCASE_2; 1.
PE 1: Evidence at protein level;
KW Allosteric enzyme {ECO:0000256|ARBA:ARBA00022533};
KW Carbon dioxide fixation {ECO:0000256|ARBA:ARBA00023300};
KW Lyase {ECO:0000256|ARBA:ARBA00023239};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Photosynthesis {ECO:0000256|ARBA:ARBA00022531};
KW Proteomics identification {ECO:0007829|PeptideAtlas:A0A1D6MNB9};
KW Pyruvate {ECO:0000313|EMBL:ONM30617.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000007305}.
FT REGION 394..419
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 394..414
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 154
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10111"
FT ACT_SITE 701
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10112"
SQ SEQUENCE 1034 AA; 115323 MW; 886E3700198B05B3 CRC64;
MLDTTDDIAE GISFQAFEDD CRLLASLLHD VLLRELGPRF IKILERNRIL AQSAVSMRAA
GMEDTAAVVE RQLETDLAAM PLEDALCLAR AFSHYLNLMG IAETHHRVRK ARNMEQLSKS
CDDIFNKLIQ SGVPSEQLYD TVCKQEVEIV LTAHPTQINR RTLQYKHLRV AHLLEFNGRP
DLSHEDKEML IEDLVREITA IWQTDELRRH KPTPVDEARA GLHIVEQSLW KAVPHYLRRV
SSALKKHTGS PLPLTCTPIK FGSWMGGDRD GNPNVTAKVT RDVSLLSRWM AIDLYIQELD
NLSFELSVNG CSDKVASLAN DILLKAAEDL KANTWNKTVP QNNAKLHNLA LPAQLPSGAD
LPSCTECSDG ESQFRMINLP RNSNRPGALN LTEKFEDSPL SSPTGRQSHI ARTPSGRQPR
KLFKESNIGR SSSFQKLLEP SLSDRPGITP YRVVLGNLKE KLVKTRRRLE LLLEDLPCDY
DTEEYCETSD QLLEPLLLCH QSLQSCGSSV LADGRLADLI RRVATFGMVL MKLDVRQESG
RHTEALDSVT SYLDLGVYSE WDEEKKLDFL TRELKGKRPL VPQNIEVAAD VKEVLDTFKV
AAELGSDSLG AYVISMASNA SDVLAVELLQ KDARLAVSGD LGRPCPGGTL RVVPLFETVK
DLQAAGSAIR KLLSIDWYRE HIIKNHNGHQ EVMVGYSDSG KDAGRFTAAW ELYKAQEDVV
AACNEFGIKV TLFHGRGGSI GRGGGPTYLA IQSQPPGSVM GTLRSTEQGE MVQAKFGLPQ
TAVRQLEIYT TAVLLATLRP PHPPRDANWR NVMEEISRVS CAHYRSTVYE DPEFITYFHE
ATPQAELGHL NIGSRPAKRK PAGGISSLRA IPWVFAWTQT RLVLPAWLGV GTGLQDALDR
GHGEELRAMY AEWPFFQSTL DLIEMVTAKA DAPMAAHYEE MLVARERRGV GAGLRRELAR
TERCVLAVSG HSKLTAHNRS LRRLIESRLA YLNPINMLQV EVLRRLRRDD DNRRLRDALL
ITINGIAAGM RNTG
//
