ID A0A1D6MQV6_MAIZE Unreviewed; 1107 AA.
AC A0A1D6MQV6;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=Phospholipid-transporting ATPase {ECO:0000256|RuleBase:RU362033};
DE EC=7.6.2.1 {ECO:0000256|RuleBase:RU362033};
DE Flags: Fragment;
GN ORFNames=ZEAMMB73_Zm00001d040456 {ECO:0000313|EMBL:ONM31385.1};
OS Zea mays (Maize).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX NCBI_TaxID=4577 {ECO:0000313|EMBL:ONM31385.1};
RN [1] {ECO:0000313|EMBL:ONM31385.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Seedling {ECO:0000313|EMBL:ONM31385.1};
RG Maize Genome Sequencing Project;
RA Ware D.;
RT "Update maize B73 reference genome by single molecule sequencing
RT technologies.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O + phospholipidSide 1 = ADP + phosphate +
CC phospholipidSide 2.; EC=7.6.2.1;
CC Evidence={ECO:0000256|ARBA:ARBA00034036,
CC ECO:0000256|RuleBase:RU362033};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU362033}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU362033}.
CC -!- SIMILARITY: Belongs to the cation transport ATPase (P-type) (TC 3.A.3)
CC family. Type IV subfamily. {ECO:0000256|ARBA:ARBA00008109,
CC ECO:0000256|RuleBase:RU362033}.
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DR EMBL; CM007649; ONM31385.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1D6MQV6; -.
DR OMA; TGSETRI; -.
DR ExpressionAtlas; A0A1D6MQV6; baseline and differential.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0140326; F:ATPase-coupled intramembrane lipid transporter activity; IEA:UniProtKB-EC.
DR GO; GO:0000287; F:magnesium ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0015914; P:phospholipid transport; IEA:InterPro.
DR CDD; cd02073; P-type_ATPase_APLT_Dnf-like; 1.
DR Gene3D; 3.40.1110.10; Calcium-transporting ATPase, cytoplasmic domain N; 1.
DR Gene3D; 2.70.150.10; Calcium-transporting ATPase, cytoplasmic transduction domain A; 1.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR InterPro; IPR023299; ATPase_P-typ_cyto_dom_N.
DR InterPro; IPR018303; ATPase_P-typ_P_site.
DR InterPro; IPR023298; ATPase_P-typ_TM_dom_sf.
DR InterPro; IPR008250; ATPase_P-typ_transduc_dom_A_sf.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR023214; HAD_sf.
DR InterPro; IPR006539; P-type_ATPase_IV.
DR InterPro; IPR032631; P-type_ATPase_N.
DR InterPro; IPR001757; P_typ_ATPase.
DR InterPro; IPR032630; P_typ_ATPase_c.
DR InterPro; IPR044492; P_typ_ATPase_HD_dom.
DR NCBIfam; TIGR01652; ATPase-Plipid; 1.
DR NCBIfam; TIGR01494; ATPase_P-type; 1.
DR PANTHER; PTHR24092:SF207; PHOSPHOLIPID-TRANSPORTING ATPASE; 1.
DR PANTHER; PTHR24092; PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE; 1.
DR Pfam; PF13246; Cation_ATPase; 1.
DR Pfam; PF16212; PhoLip_ATPase_C; 1.
DR Pfam; PF16209; PhoLip_ATPase_N; 1.
DR PRINTS; PR00121; NAKATPASE.
DR SFLD; SFLDS00003; Haloacid_Dehalogenase; 1.
DR SFLD; SFLDF00027; p-type_atpase; 1.
DR SUPFAM; SSF81653; Calcium ATPase, transduction domain A; 1.
DR SUPFAM; SSF81665; Calcium ATPase, transmembrane domain M; 1.
DR SUPFAM; SSF56784; HAD-like; 1.
DR SUPFAM; SSF81660; Metal cation-transporting ATPase, ATP-binding domain N; 1.
DR PROSITE; PS00154; ATPASE_E1_E2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|RuleBase:RU362033};
KW Magnesium {ECO:0000256|RuleBase:RU362033};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362033};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU362033};
KW Translocase {ECO:0000256|ARBA:ARBA00022967, ECO:0000256|RuleBase:RU362033};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362033};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362033}.
FT TRANSMEM 346..368
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362033"
FT TRANSMEM 400..421
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362033"
FT TRANSMEM 946..965
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362033"
FT TRANSMEM 977..994
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362033"
FT TRANSMEM 1023..1045
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362033"
FT TRANSMEM 1057..1074
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362033"
FT TRANSMEM 1081..1101
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362033"
FT DOMAIN 93..146
FT /note="P-type ATPase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16209"
FT DOMAIN 910..1105
FT /note="P-type ATPase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF16212"
FT NON_TER 1107
FT /evidence="ECO:0000313|EMBL:ONM31385.1"
SQ SEQUENCE 1107 AA; 122970 MW; A036EAECA28588B6 CRC64;
MASERPLLIA TTPGASTPDD APSPHPPAAS LLPPAQSEPP LRADRLAFSV EIPDPFRSYR
RGDGPAADPS ASLERERDVG DDESREVIVG ESSPEFSGNA IRTAKYSFLT FLPRNLFEQF
RRLSYVYFLA ITVLNQLPQV AVFGRGASVL PLAFVLFVTA VKDAYEDFRR HRSDRQENNR
LATVLALGTA GEFQPKRWKH IRVGDVVRIE SNETLPADMV LLATSDPTGV AHVQTVNLDG
ETNLKTRYAK QETHVMFSQN GGVGGVLHCE RPNRNIYGFQ ANLEIDGKRV SLGPSNIVLR
GCELKNTTWA IGVVVYAGKE TKVMLNSSGA PSKRSRLETQ LNRETVILSI MLIGMCTTAS
VLAGIWLLNH RRELEFTQFF REKDYTTGKN YNYYGVGMQI FITFLMAVIV YQVIIPISLY
ISMELVRLGQ AYFMGADKDL YDESSRSKFQ CRALNINEDL GQIRYVFSDK TGTLTENKMV
FQCASIRGVD YNSGKDTGGY SVVVGDHLWT PKMSVKIDPE LVKLLRDGGS NEEPKLVLEF
LLALASCNTI VPLVLDTRDS KQKLIDYQGE SPDEQALAYA AASYGIVLVE RTSGYIVIDV
LGDRQRFDIL GLHEFDSDRK RMSVIVGCPD KTVKLYVKGA DSSVFGITNN SSELDIVRAT
EAHLHKYSSL GLRTLVVGMR KLSQSEFEEW QLAYENASTA VLGRGNLLRS VAANIEINVN
ILGATGIEDK LQDGVPEAIE SIRQADIKVW ILTGDKQETA ISIGYSCKLL TNDMTQIVIN
NNSKESCQRS LVEALATTKK LRAASSIGTQ GPLLASETSN VTLALIVDGN SLVYILETDL
QDELFKLATE CSVVLCCRVA PLQKAGIVAL IKNRTNDMTL AIGDGANDVS MIQMADVGIG
ISGQEGRQAV MASDFSMGQF RFLVPLLLVH GHWNYQRMAY MILYNFYKNA MFVLVLFWYV
LYTAFTLTTA ITEWSSLLYT VLYTSLPTIV VGILDKDLNK ATLIAYPKLY GSGQRDDKYN
VNLFVLNMLE ALWQSLVVFY LPYFAYRRST IDMSSLGDLW ALAPVIVVNM QLAMDIIRWN
WIIHAFVWGT IAATTVCLFV IDSIWVL
//
