ID   A0A1D6NPG6_MAIZE        Unreviewed;       824 AA.
AC   A0A1D6NPG6;
DT   30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2016, sequence version 1.
DT   27-MAR-2024, entry version 44.
DE   SubName: Full=E3 SUMO-protein ligase SIZ1 {ECO:0000313|EMBL:ONM41936.1};
GN   ORFNames=ZEAMMB73_Zm00001d044602 {ECO:0000313|EMBL:ONM41936.1};
OS   Zea mays (Maize).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC   Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX   NCBI_TaxID=4577 {ECO:0000313|EMBL:ONM41936.1};
RN   [1] {ECO:0000313|EMBL:ONM41936.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   TISSUE=Seedling {ECO:0000313|EMBL:ONM41936.1};
RG   Maize Genome Sequencing Project;
RA   Ware D.;
RT   "Update maize B73 reference genome by single molecule sequencing
RT   technologies.";
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- PATHWAY: Protein modification; protein sumoylation.
CC       {ECO:0000256|ARBA:ARBA00004718}.
CC   -!- SIMILARITY: Belongs to the PIAS family.
CC       {ECO:0000256|ARBA:ARBA00005383}.
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DR   EMBL; CM007649; ONM41936.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1D6NPG6; -.
DR   SMR; A0A1D6NPG6; -.
DR   IntAct; A0A1D6NPG6; 10.
DR   STRING; 4577.A0A1D6NPG6; -.
DR   PaxDb; 4577-GRMZM2G002999_P01; -.
DR   eggNOG; KOG2169; Eukaryota.
DR   InParanoid; A0A1D6NPG6; -.
DR   OMA; EPARNDY; -.
DR   UniPathway; UPA00886; -.
DR   ExpressionAtlas; A0A1D6NPG6; baseline and differential.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0061665; F:SUMO ligase activity; IBA:GO_Central.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016925; P:protein sumoylation; IBA:GO_Central.
DR   CDD; cd15570; PHD_Bye1p_SIZ1_like; 1.
DR   CDD; cd16792; SP-RING_Siz-like; 1.
DR   Gene3D; 1.10.720.30; SAP domain; 1.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR   InterPro; IPR003034; SAP_dom.
DR   InterPro; IPR036361; SAP_dom_sf.
DR   InterPro; IPR031141; SIZ1/2_SP-RING.
DR   InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR   InterPro; IPR011011; Znf_FYVE_PHD.
DR   InterPro; IPR004181; Znf_MIZ.
DR   InterPro; IPR001965; Znf_PHD.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   PANTHER; PTHR10782:SF42; E3 SUMO-PROTEIN LIGASE SIZ2; 1.
DR   PANTHER; PTHR10782; ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF02037; SAP; 1.
DR   Pfam; PF02891; zf-MIZ; 1.
DR   SMART; SM00249; PHD; 2.
DR   SMART; SM00513; SAP; 1.
DR   SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR   SUPFAM; SSF68906; SAP domain; 1.
DR   PROSITE; PS50800; SAP; 1.
DR   PROSITE; PS01359; ZF_PHD_1; 1.
DR   PROSITE; PS51044; ZF_SP_RING; 1.
PE   3: Inferred from homology;
KW   Ligase {ECO:0000313|EMBL:ONM41936.1};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00452}.
FT   DOMAIN          16..50
FT                   /note="SAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50800"
FT   DOMAIN          350..433
FT                   /note="SP-RING-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51044"
SQ   SEQUENCE   824 AA;  89754 MW;  805841C4207BF44F CRC64;
     MASPDDPVLS ACKKNLSHFR IKELKDVLHQ LGLSKQGKKQ DLVDRVMAVL LSQQDQAFET
     NGLPKAKSAV KIVEDTFRKM QDPTNTVAVS RSHELGDSVT CKKKPDDSAQ AVKVRCPCGD
     SKPNDSMIKC IDPQCNIWQH VGCVVIPDTE KSADNISPEL PSCFYCEVCR LSRADPFWVT
     VNHLLLPILI GPSTVAADGS YTVQYTAKSF QLSRANREIL QQAECNIQVW CILLSDKVPF
     RMHWPLHSDM QVNGIYVRVV NRQPTQKLGA NGRDDGPLLT DYLKEGPNKI SLSRNDTRTF
     CLGIRIAKRR SLEQVLNLVP KEQDGENFDD ALARVRRCVG GGAEANNADS DSDIEVVADF
     VSVNLRCPMT ASRIQIAGRF KSCAHMGCFD LEAFIEINQR SRKWQCPICL KNYSLENIII
     DPYFNRITSL IKSCGDDTSE IDVKPDGSWR VKGRPKLKDL TQWHLPDGTL SLSTDTAAKP
     GMCIVKHEVK EEPLSEEVGC HLKLGLRKKS NGQWEISKRV DADLVPSSGN DHDHSGHDEN
     KNCITHSSNI DDTNIADEGY NLEPATNGYP MTHVHDLDSS SADENGPPAS TGQDIVVLSD
     SDDDAIMVLS PGAVNCGSMH NTGNLFPPNT PENLGVCSGE TGGCPKETSF LALKEDFGDP
     GLSFWESHGS PRDASTSQIP DASTKAVDNP GEVDNYPAND QSKQGQVSGA DFGVAANPVP
     LEDGHDSALQ PCSMSERDSA MGLASLGADT QSCVDVHSDN WTSVSISGRD EVLTAAKIAS
     RKRSNPGDRI EDLDDDFESA PIVPTVSSPS LCHCTNVSES LAGL
//