ID   A0A1D6PBE8_MAIZE        Unreviewed;      1562 AA.
AC   A0A1D6PBE8;
DT   30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2016, sequence version 1.
DT   22-FEB-2023, entry version 36.
DE   SubName: Full=Guanine nucleotide exchange factor SPIKE 1 {ECO:0000313|EMBL:AQL06961.1};
GN   ORFNames=ZEAMMB73_Zm00001d047540 {ECO:0000313|EMBL:AQL06961.1};
OS   Zea mays (Maize).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC   Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX   NCBI_TaxID=4577 {ECO:0000313|EMBL:AQL06961.1};
RN   [1] {ECO:0000313|EMBL:AQL06961.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Seedling {ECO:0000313|EMBL:AQL06961.1};
RG   Maize Genome Sequencing Project;
RA   Ware D.;
RT   "Update maize B73 reference genome by single molecule sequencing
RT   technologies.";
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the DOCK family. {ECO:0000256|PROSITE-
CC       ProRule:PRU00983}.
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DR   EMBL; CM000785; AQL06961.1; -; Genomic_DNA.
DR   ExpressionAtlas; A0A1D6PBE8; baseline.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   CDD; cd08679; C2_DOCK180_related; 1.
DR   CDD; cd11684; DHR2_DOCK; 1.
DR   Gene3D; 1.20.58.740; -; 1.
DR   Gene3D; 1.25.40.410; -; 1.
DR   Gene3D; 2.60.40.150; C2 domain; 1.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR027007; C2_DOCK-type_domain.
DR   InterPro; IPR035892; C2_domain_sf.
DR   InterPro; IPR026791; DOCK.
DR   InterPro; IPR043161; DOCK_C_lobe_A.
DR   InterPro; IPR043162; DOCK_C_lobe_C.
DR   InterPro; IPR027357; DOCKER_dom.
DR   InterPro; IPR046769; DOCKER_Lobe_A.
DR   InterPro; IPR046770; DOCKER_Lobe_B.
DR   InterPro; IPR046773; DOCKER_Lobe_C.
DR   PANTHER; PTHR23317; DEDICATOR OF CYTOKINESIS DOCK; 1.
DR   PANTHER; PTHR23317:SF76; LD20667P; 1.
DR   Pfam; PF06920; DHR-2_Lobe_A; 1.
DR   Pfam; PF20422; DHR-2_Lobe_B; 1.
DR   Pfam; PF20421; DHR-2_Lobe_C; 1.
DR   Pfam; PF14429; DOCK-C2; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   PROSITE; PS51650; C2_DOCK; 1.
DR   PROSITE; PS51651; DOCKER; 1.
PE   3: Inferred from homology;
KW   Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553}.
SQ   SEQUENCE   1562 AA;  175761 MW;  E36A818A8219692B CRC64;
     MPCKESFAWA MIPLFEGNHA GGLSDAASPS SPLATSLPGS TSQDSIVDPI LKLTLDGKVN
     HYSSGSSVIV EISNLNKVKE SYIVDSLQDP KRKVHKPVKG VLRLEVEKLH GGHNDVDNTS
     EGGSMANDLN DAGDINNGRS NRSSFDGIHS FVNSIAIAQK DAHHNGIISN AENGDNFEAF
     DFRMLTRSEP FSQLFHCLYV YPLTVSLSRK RNLFVRVELR KDDSDIRKPP LEAVHPRERN
     MMLQKWGHTQ IAVGTRMASY HDEVKISLPA LLTPQHHLVF TFFHVDLQMK LEAPKPVIVG
     HSVLPLSTHI QLLSDVSLPI LRELVPHYLQ GSGKERMDYL EDGKTVFKLR LRLCSSLFPV
     NERIRDFFVE YDRHTLHTSP PWGSELLEAI NSLKNVESTA LLQFLQPILN MLLHLIGDGG
     ETLQVAAFRA MVNILTRVQQ ESSDGAERNR FLINYVDFAF DDFGGRQAPV YPGLSTVWGS
     LARSKAKGYR VGPVYDDVLA MAWFFLELIV KSMGLEQSRL FYHNLPLGED VPPLQLKEGV
     FRCIMQLFDC LLTEVHERCK KGLSLAKRLN STLAFFCYDL LSIIEPRQVF ELVSLYMDKF
     AGVCQAVLHD CKLTFLQIIC DHDLFVEMPG RDPSDRNYLS SVLIQEIFLT LDHDDLSQRA
     KAARILVVLI CKHEFDARYQ KSEDKLYIAQ LYFSLIGQIL DEMPVFYNLN AIEKREVLVV
     ILQIVRNLDD ATLIKAWQQS IARTRLFFKL LEECITHFEH NKTGGSMLLG ASSRSPDVER
     PAPPKYSERL SPSVNAYLSE ASRHEIRPQG TPENGYMWNR VSPQLSSPNQ PYSLREALAQ
     AQSSRIGSTA RALRESLHPV LRQKLELWEE NLSTAVSLEV LRITEKFSAA AGTRSITTDY
     AKLDCVTSIV MGLLSRSQPL AFWKAFLPVV YNIFNLHGAT LMARENDRFL KQIAFHLLRL
     AVFRNDSIRK RAVVGLQILV RNAFNYFKNT TRLRVMLTIT LSELLSDVQV TQMKSDGSLE
     ESGEARRLRK SLEEMADVRS KDLLKDCGLP VTALEAAPDG SSDNMWSWAE VKHLSKCLVQ
     ALDAGLEHAL LDSVVTVDRY AAAEGFYKLA MAYAPVPDLH IMWLQHLCDA HQEMQSWAEA
     AQCAVAAAGV IMQALVGRND AVWSKEHVTS LHKICPIVNT DVSAEASAAE VEGYGASKLT
     VDSAVKYLQL ANKLFTQAEL YHFCASIQEL IIPVYKSRRA YGQLAKCHTS LTNIYESILE
     QEASPIPFID ATYYRVGFYG ERFGKLNKKE YVFREPRDVR LGDIMEKLSH IYEVKMDGSH
     TLHIIPDSRQ VNADELQPGV CYLQITAVDP VMEDEDLGSR RERIFSLSTG TVRARVFDRF
     LFDTPFTKNG KTQGGLEDQW KRRTVLQTEG SFPALVNRLP VTKSESLEFS PVENAIGMIE
     TRTAALRNEL EEPRSSEGDQ LPRLQSLQRI LQGSVAVQVN SGVLSVCTAF LSGEPATRLR
     SQELQQLIAA LLEFMAVCKR AIRVHFRLIG EEDQEFHTQL VNGFQSLTAE LSHYIPAILS
     EL
//