ID   A0A1D6PLI5_MAIZE        Unreviewed;       440 AA.
AC   A0A1D6PLI5;
DT   30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2016, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   SubName: Full=DNA (Cytosine-5)-methyltransferase DRM2 {ECO:0000313|EMBL:AQL10066.1};
GN   ORFNames=ZEAMMB73_Zm00001d048516 {ECO:0000313|EMBL:AQL10066.1};
OS   Zea mays (Maize).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC   Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX   NCBI_TaxID=4577 {ECO:0000313|EMBL:AQL10066.1};
RN   [1] {ECO:0000313|EMBL:AQL10066.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Seedling {ECO:0000313|EMBL:AQL10066.1};
RG   Maize Genome Sequencing Project;
RA   Ware D.;
RT   "Update maize B73 reference genome by single molecule sequencing
RT   technologies.";
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC       superfamily. C5-methyltransferase family. {ECO:0000256|PROSITE-
CC       ProRule:PRU01016}.
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DR   EMBL; CM000785; AQL10066.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1D6PLI5; -.
DR   ExpressionAtlas; A0A1D6PLI5; baseline.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006306; P:DNA methylation; IEA:InterPro.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 2.
DR   InterPro; IPR001525; C5_MeTfrase.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   InterPro; IPR030380; SAM_MeTfrase_DRM.
DR   InterPro; IPR015940; UBA.
DR   PANTHER; PTHR23068:SF25; DNA (CYTOSINE-5)-METHYLTRANSFERASE DRM2; 1.
DR   PANTHER; PTHR23068; DNA CYTOSINE-5- -METHYLTRANSFERASE 3-RELATED; 1.
DR   Pfam; PF00145; DNA_methylase; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 2.
DR   PROSITE; PS51679; SAM_MT_C5; 1.
DR   PROSITE; PS51680; SAM_MT_DRM; 1.
DR   PROSITE; PS50030; UBA; 1.
PE   3: Inferred from homology;
KW   Methyltransferase {ECO:0000256|ARBA:ARBA00022603, ECO:0000256|PROSITE-
KW   ProRule:PRU01016};
KW   S-adenosyl-L-methionine {ECO:0000256|PROSITE-ProRule:PRU01016};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PROSITE-
KW   ProRule:PRU01016}.
FT   ACT_SITE        401
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01016"
SQ   SEQUENCE   440 AA;  49607 MW;  E7F69D1487DAF83D CRC64;
     MSRKDEKVDS LVKMGFPEDE AALAITRCGD ASISVLVDSI YASQTAGDGY CGNLSDYEDN
     SYGGRSTGNK KKRKRYGGQA QGSRGPLDGS CDEPMPLPHP MVGFNLPDQW SRRVDRSLPA
     QAIGPPYFYY ENVALAPKGV WTTISRFLYD IQPEFVDSKY FCAAARKRGY IHNLPLENRS
     PLLPIPPKTI SEAFPRTKRW WPSWDPRRQF NCLQTCVSSA KLLERIRVAL TNSSDPPPPR
     VQKYVLEECR KWNLAWVGLN KVAPLEPDEM EFLLGFPKDH TRGISRTERY RSLGNSFQVD
     TVAYHLSVLK DLFPQGMNVL SLFSGIGGAE VALHRLGIQM NTVISVEKSE VNRTILKSWW
     DQTQTGTLIE ITDVQTLSSE RIEAYIRRIG GFDLVIGGSP CNNLTGSNRH HRDGLEGEHS
     ALFHHYFRIL HAVKSIMERL
//