ID A0A1D6Q0G5_MAIZE Unreviewed; 499 AA.
AC A0A1D6Q0G5;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=phosphatidylinositol 3-kinase {ECO:0000256|ARBA:ARBA00012073};
DE EC=2.7.1.137 {ECO:0000256|ARBA:ARBA00012073};
GN ORFNames=ZEAMMB73_Zm00001d050219 {ECO:0000313|EMBL:AQK52130.1};
OS Zea mays (Maize).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX NCBI_TaxID=4577 {ECO:0000313|EMBL:AQK52130.1};
RN [1] {ECO:0000313|EMBL:AQK52130.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Seedling {ECO:0000313|EMBL:AQK52130.1};
RG Maize Genome Sequencing Project;
RA Ware D.;
RT "Update maize B73 reference genome by single molecule sequencing
RT technologies.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CM000780; AQK52130.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1D6Q0G5; -.
DR ExpressionAtlas; A0A1D6Q0G5; baseline and differential.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0046854; P:phosphatidylinositol phosphate biosynthetic process; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd00896; PI3Kc_III; 1.
DR Gene3D; 1.10.1070.11; Phosphatidylinositol 3-/4-kinase, catalytic domain; 1.
DR Gene3D; 1.25.40.70; Phosphatidylinositol 3-kinase, accessory domain (PIK); 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000403; PI3/4_kinase_cat_dom.
DR InterPro; IPR036940; PI3/4_kinase_cat_sf.
DR InterPro; IPR018936; PI3/4_kinase_CS.
DR InterPro; IPR001263; PI3K_accessory_dom.
DR InterPro; IPR042236; PI3K_accessory_sf.
DR InterPro; IPR015433; PI_Kinase.
DR PANTHER; PTHR10048:SF7; PHOSPHATIDYLINOSITOL 3-KINASE CATALYTIC SUBUNIT TYPE 3; 1.
DR PANTHER; PTHR10048; PHOSPHATIDYLINOSITOL KINASE; 1.
DR Pfam; PF00454; PI3_PI4_kinase; 1.
DR Pfam; PF00613; PI3Ka; 1.
DR SMART; SM00145; PI3Ka; 1.
DR SMART; SM00146; PI3Kc; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS00916; PI3_4_KINASE_2; 1.
DR PROSITE; PS50290; PI3_4_KINASE_3; 1.
DR PROSITE; PS51545; PIK_HELICAL; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:AQK52130.1};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 1..135
FT /note="PIK helical"
FT /evidence="ECO:0000259|PROSITE:PS51545"
FT DOMAIN 219..484
FT /note="PI3K/PI4K catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50290"
SQ SEQUENCE 499 AA; 56994 MW; 4ECE72C427244363 CRC64;
MSEKKALTKF VRSVDWSDNQ EAKQAVELIG KWEMIDVADA LELLSPDFES DEVRGYAVSV
LERADDEELQ CYLLQLVQAL RFERSDKSRL ALFLVNRALS NIEIASFLRW YILVELHSPA
YARRYYGTYD MLENSMMKLV GREDGDEDGF RLWQSLTRQT DLTAQLCSIM KDVRNVRGSA
QKKIEKLRQL LSGVFSELTN FDEPIRSPLA PTLLLTGVVP QESSIFKSAL NPLRLTFKTA
NGGTSKIIYK KGDDLRQDQL VIQTVSLMDR LLKLENLDLH LTPYRVLATG QDEGMLEFIS
SSSLAQILSE HRSITSYLQK FHPDEDGPFG ITAQCLETFI KSCAGYSVIT YILGVGDRHL
DNLLLTDDGR LFHVDFAFIL GRDPKPFPPP MKLCKEMVEA MGGAESQYYT RFKSYCCEAY
NILRKSSSLI LNLFKLMERS GIPDISADES GGLKLQEKFR LDLDDEEAIH FFQDLINDSV
SALFPQMVET IHRWAQYWR
//
