ID   A0A1D6Q1D7_MAIZE        Unreviewed;      1548 AA.
AC   A0A1D6Q1D7;
DT   30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 2.
DT   27-MAR-2024, entry version 27.
DE   RecName: Full=ATP-dependent DNA helicase {ECO:0000256|RuleBase:RU363044};
DE            EC=3.6.4.12 {ECO:0000256|RuleBase:RU363044};
GN   ORFNames=ZEAMMB73_Zm00001d050378 {ECO:0000313|EMBL:AQK52428.1};
OS   Zea mays (Maize).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC   Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX   NCBI_TaxID=4577 {ECO:0000313|EMBL:AQK52428.1};
RN   [1] {ECO:0000313|EMBL:AQK52428.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Seedling {ECO:0000313|EMBL:AQK52428.1};
RG   Maize Genome Sequencing Project;
RA   Ware D.;
RT   "Update maize B73 reference genome by single molecule sequencing
RT   technologies.";
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC         Evidence={ECO:0000256|RuleBase:RU363044};
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|RuleBase:RU363044};
CC   -!- SIMILARITY: Belongs to the helicase family.
CC       {ECO:0000256|RuleBase:RU363044}.
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DR   EMBL; CM000780; AQK52428.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1D6Q1D7; -.
DR   SMR; A0A1D6Q1D7; -.
DR   InParanoid; A0A1D6Q1D7; -.
DR   ExpressionAtlas; A0A1D6Q1D7; baseline.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0000723; P:telomere maintenance; IEA:InterPro.
DR   CDD; cd18809; SF1_C_RecD; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   Gene3D; 2.40.160.10; Porin; 1.
DR   InterPro; IPR010285; DNA_helicase_pif1-like.
DR   InterPro; IPR025476; Helitron_helicase-like.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR049163; Pif1-like_2B_dom.
DR   InterPro; IPR023614; Porin_dom_sf.
DR   PANTHER; PTHR10492:SF94; ATP-DEPENDENT DNA HELICASE; 1.
DR   PANTHER; PTHR10492; UNCHARACTERIZED; 1.
DR   Pfam; PF14214; Helitron_like_N; 1.
DR   Pfam; PF05970; PIF1; 1.
DR   Pfam; PF21530; Pif1_2B_dom; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|RuleBase:RU363044};
KW   DNA damage {ECO:0000256|RuleBase:RU363044};
KW   DNA recombination {ECO:0000256|RuleBase:RU363044};
KW   DNA repair {ECO:0000256|RuleBase:RU363044};
KW   Helicase {ECO:0000256|RuleBase:RU363044};
KW   Hydrolase {ECO:0000256|RuleBase:RU363044};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU363044}.
FT   DOMAIN          475..607
FT                   /note="Helitron helicase-like"
FT                   /evidence="ECO:0000259|Pfam:PF14214"
FT   DOMAIN          1234..1280
FT                   /note="DNA helicase Pif1-like 2B"
FT                   /evidence="ECO:0000259|Pfam:PF21530"
SQ   SEQUENCE   1548 AA;  175158 MW;  80479E31444E97C3 CRC64;
     MDQMGYNADR TPFTNISNTI ITSNQNESNS LGPIVDAREH KRQRDRERYA AMTVEQKNEK
     NRKRREARQR NKGLPIKTQS SIDSFPDDCS TIDFRILSTQ GIAGCVHESV DNTPNHTMKR
     AAYFSERYKN LTPVDRESRR ERLRLYNKTP KRKDAKTEYD RKRRALQSDT LNQESIAMED
     PTYTPEVGRH RTDATQPYGS SVTTCDWVIP EFVGTPFLPT LIQTEDVGSL TMSTEPLSRK
     HHVLSGARPA ILGDDDEGVI FEEDDDDNDG YLFAGQYDET DEDIKIDGTQ DESIDTDLPD
     TYNKVYNNVP EETHMLKSVP NCGYCNAKKF EYEPPGFCCR GGKIVSILCE NPYSEHLRSM
     GHVENLDDYR ITLNLDQSLN QKTYNTPITS EVAAVWIEGS ERRGQFNKSV MLHGKDRSSH
     GIRSYHGCYD ALSYPLFFPR GELGWHANIP KVGVSMGEVD VYRATHRASN ANDEDADLYQ
     GLVDTMLDGD IRAEKVGKRT VLSSSFIDGP HDMRRQYMDA MALVRKFGKP DIFLTMTCNP
     NWDEIRRELL PGQTPQDRSD LVVRVFHVKL QELKYRLTKQ DILGKVRAYV YVVEFQKRGL
     PHAHFLLIMQ RKYELTCPEQ YDLLISAEIP DKKYHELGKM VIKHMMHGPC GSLNPNCPCT
     KGRASCKNHY PRPFSDATLQ GKDSYPVYRR RDDGRKEKAC GSIKAVKYLF KYIYKGHDRV
     CVVMRDASKT DDDVDEIKQY RDARWVTPPK ALWRIYGFEL SQNSPPVMQL QLHLPNMHMV
     AFHDRQMSGK GKVWQRRKRD TGGQVGRIVS AHPAEGERYY LRVLLNHVAG AISYVDLRTV
     DGVTLLTFRE AVERRGLLES DNTLDECLTE RALFQMPLTL RQLFATILVY CEPSDVAVLW
     RKHLDAMSED YQRRSESKTH VEQMVLIDIR NMLQSMGKDL KTFPLPPIID TYDDAIGTAR
     EVYEEESIEP TVADVALKET LNEEQRAAYD KIMSAVDTDH GGLFFVDGPG GTGKTYLYRV
     LLATLRSQNK IVVATTTSGV AASIMPGGRT AHSRFKIPLT IDDGVVCSFT KQSGTAELLR
     KASLIIWDEA SMTKRQAVEA LDNSMRDIMG RPGLPFGGKT IVFGGDFRQV LPVVRKGSRA
     QVVASSLRMS YLWESMSHLK LVSNMRAKND PWFAEFLLRI GGGTEVTNRD GDIRLPSEVD
     MINVKMIDRF QGAHTVYHSF DSAMDDPHNY YPPEFLNTLT PNGLPPHVLK LKIGCPVILL
     RNIDSANGLC NGTRLVVRGF QRNSIDAKIV LGQHAGKRIF LPRIPLCPSD DEMFPFQFNR
     KQFPIRLSFA MTVNKAQGQT IPNVGVYLPE SVFSHGQLYV ALSRATARSN IKILVIPAVD
     GNKRSRKGVR KNPTVDCGTY TKNIVYKELE ISSMADTRDI TALSTMRNES IISEIQAQLK
     HKNVTVDVKA NSDPHISPIQ LSTTVTVEEL GLPGLKNIMA ISYPHQAFGR ERQRGQPHCV
     LHSYHLANTE KDTTVGMEVT RNFSTKASIV TFGTCHALDP TTTMKACN
//