ID   A0A1D6QDP9_MAIZE        Unreviewed;      2094 AA.
AC   A0A1D6QDP9;
DT   30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2016, sequence version 1.
DT   22-FEB-2023, entry version 28.
DE   RecName: Full=separase {ECO:0000256|ARBA:ARBA00012489};
DE            EC=3.4.22.49 {ECO:0000256|ARBA:ARBA00012489};
GN   ORFNames=ZEAMMB73_Zm00001d052143 {ECO:0000313|EMBL:AQK56304.1};
OS   Zea mays (Maize).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC   Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX   NCBI_TaxID=4577 {ECO:0000313|EMBL:AQK56304.1};
RN   [1] {ECO:0000313|EMBL:AQK56304.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Seedling {ECO:0000313|EMBL:AQK56304.1};
RG   Maize Genome Sequencing Project;
RA   Ware D.;
RT   "Update maize B73 reference genome by single molecule sequencing
RT   technologies.";
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=All bonds known to be hydrolyzed by this endopeptidase have
CC         arginine in P1 and an acidic residue in P4. P6 is often occupied by
CC         an acidic residue or by a hydroxy-amino-acid residue, the
CC         phosphorylation of which enhances cleavage.; EC=3.4.22.49;
CC         Evidence={ECO:0000256|ARBA:ARBA00000451};
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DR   EMBL; CM000780; AQK56304.1; -; Genomic_DNA.
DR   ExpressionAtlas; A0A1D6QDP9; baseline and differential.
DR   GO; GO:0005634; C:nucleus; IEA:InterPro.
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0098813; P:nuclear chromosome segregation; IEA:UniProt.
DR   GO; GO:0000280; P:nuclear division; IEA:UniProt.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   InterPro; IPR005314; Peptidase_C50.
DR   InterPro; IPR030397; SEPARIN_core_dom.
DR   PANTHER; PTHR12792; EXTRA SPINDLE POLES 1-RELATED; 1.
DR   PANTHER; PTHR12792:SF0; SEPARIN; 1.
DR   Pfam; PF03568; Peptidase_C50; 1.
DR   PROSITE; PS51700; SEPARIN; 1.
PE   4: Predicted;
KW   Chromosome partition {ECO:0000256|ARBA:ARBA00022829};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
SQ   SEQUENCE   2094 AA;  233370 MW;  DBDDF7351C7838C9 CRC64;
     MEAAAADLIA ALSSPSSFAG LYSRFAAYLQ PFTPYLHSSN PNTKPPQKRA TKQNKQPPPP
     DAATLRPLAK RFLPFLGRAL HLLPPLVRAC PVSGDKGGEA ADELLEIYGL LLDCLEAISP
     CLAGKPYSVL LQRGRFICCL ESRGHFARAS AEAAATLDAL RSALSPPTTS TKSRRGAAGV
     DPVLLPDPGS AGEAGTDPEV TLLAVELTVC LANCSSKGKV KEPTPYERLI SLFKQLKPWL
     RILTNEVSRK YLPLLMNAMS RCTLFLVSES SLFNTDLVHG FCRYTMQECV GEGMIELLPA
     IARKICSSVD LTWGGSTQLL LHVLKTVTDS VVRLKDDLPK SVNELLVFVA YFCRFILSAN
     RDLSVGASEL LYKQGGYFSE VSSPTASMLL LYATGLYLSA QQAESEIPPY LSVGIPKDQK
     YLHALEKGLG TLARCPHDNT SLVTYLDSLE FISKILSQQV NTLWKDFSEG KPTHYSGNMD
     YVLTALHQFI DSSFTSFSCR QMSQGDNERQ HEQHGTLLTV LVSAIKFSFL TKKDIQKSLG
     FIVCAISSKW FTLEELKFLI PSLGNIGVTL HNTGHVKEAP KALELCCQTI WAHISLFYYR
     LSSRTKGNDI MTDLSMDTLK DMDIILDAFS RIAKMVDALC RCGTEIETPL VIVAKSLSIM
     LPDGDNSEYN KCSFILIKAW VKAVHKDFRD TKVDDAPLLY PFLLKYRSPW PIKLIGLIVE
     QELLAYGLTE ARSIEFCSKM QIRIIDVLLH KIYCTKEHFL ERSRVLIRKA GALRASGVEN
     IKNCLESLRD AISLLVIFDS AEKALNLWLD MEAFDHSSSD MVLQQPSKTI VPLICFLVDL
     LSMKGCFELQ FKLCKVMIMI WKQEKLPIEK LLSLLFTSGR LSHACCYLPL DERFLSIAKE
     HLGVCCHDIE FWINCFKGDH PSLCMFLQRT LPSALFIPQS CKHPFGRQFS FVTSVDEVSK
     VASSLVSGDT SNEQSTFLAG CLYYDLSEKV FSRGQLFQAF SYGNKALHLR KKLLKKKFKI
     NSGISGNMER QHCGQDISLE VCGPTIVEIW PNSSSSVNTK DFFLTPWNVL RCYLESTLQV
     AMMHELIGNG AEAEVLLQTG KEISNFHGLS VFCIVFTSFL GQLYCKRQLW DEAESELNYA
     RDLVKNDATI SCKLCSLTLG ISVDMQVGDL SWSLFEKKIH KQITAGLSNT LGMYQSAIDK
     LNSTNLEYCN GSFDRHTTGY LVCSKDCIPS KYEACNLGAE PLTSNDGLLS PCSVCMVIQV
     RRKNSGNAEA GPPLDAKARR SSRNSSRLAK GQNVETLAKT RTRSSKRNAC MKSEKVLTEL
     NSKNNVTGSK ELAADASVCG EAECFPDGID HSKDDLCNMF GCWSCLFIKS LNSGCIQNIL
     QLRLDYVHRH YLVSLLLKKA RALGSHSNGD CEVHSVYWKC ISLLFFRSLP QDCCRTYGPY
     LIGLIMDRSI GDFLPLECAE ILFNMSFFLL KSPLSEQSRD ICCIFSSVTM ADVVPWLLKA
     FVLSRESPSL VQEVCKLLAC IFLLSTTDSS IQLPLGSHKE SLSLNHWATY FHQVSVGTNL
     NCHYFASLQA SSEEKVPKDT YKDFRNETDD NVSKFLRLSS RDIKYIEKHM TEFFQKLPDV
     PVLCISMLGG DYVNALLKFH CHPPFFPAWM LLSRFDSTNE PTTLLLPVDS ISEMQFEDSC
     TKDLGNPTRV LDKWQCPWGY GITDYVAPVF RNILEENFMS LSSATLTIDD VNADRVRWWS
     HRMKLNNYLA NTLKDIEDSW FGPWKCLLLG HQLSDEHIET ASSMIITGLD TEFEFEVNPM
     LIKAILGGAV SVDEVQECFL QLILYKGYFG RGGCCGKDRL KAFSSCQMDD GSMETLKRII
     TDASYELPQP ADRDPVILVL DVNVQGVAGN SPKADELVLA LTNHDLFLYF GHGSGTQYIS
     SKEVEKIDNC AAALLMGCSS GTLHCKGSYA PRGAPLSYLF AGSPAIIANL WDVSDKDIDR
     FSKALLNSWL HDKSLDGNNC SKCCQLTMEL ESMSIASKEN GKARRQGTRG KKQQHINDST
     KCCSCKQRRI ASYISEARRA CRLPLLIGAS PVCYGVPTII RKKVMTDSTT REMT
//