ID   A0A1D6QID9_MAIZE        Unreviewed;       788 AA.
AC   A0A1D6QID9;
DT   30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2016, sequence version 1.
DT   22-FEB-2023, entry version 32.
DE   SubName: Full=Retinoblastoma-related protein 2 {ECO:0000313|EMBL:AQK57667.1};
GN   ORFNames=ZEAMMB73_Zm00001d052666 {ECO:0000313|EMBL:AQK57667.1};
OS   Zea mays (Maize).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC   Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX   NCBI_TaxID=4577 {ECO:0000313|EMBL:AQK57667.1};
RN   [1] {ECO:0000313|EMBL:AQK57667.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Seedling {ECO:0000313|EMBL:AQK57667.1};
RG   Maize Genome Sequencing Project;
RA   Ware D.;
RT   "Update maize B73 reference genome by single molecule sequencing
RT   technologies.";
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Regulator of biological processes that recruits a histone
CC       deacetylase to control gene transcription. May play a role in the entry
CC       into mitosis, negatively regulating the cell proliferation. Formation
CC       of stable complexes with geminiviridae replication-associated proteins
CC       may create a cellular environment which favors viral DNA replication.
CC       {ECO:0000256|ARBA:ARBA00025018}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the retinoblastoma protein (RB) family.
CC       {ECO:0000256|ARBA:ARBA00009475}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CM000780; AQK57667.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1D6QID9; -.
DR   ExpressionAtlas; A0A1D6QID9; baseline and differential.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051726; P:regulation of cell cycle; IEA:InterPro.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR   Gene3D; 1.10.472.10; Cyclin-like; 2.
DR   InterPro; IPR036915; Cyclin-like_sf.
DR   InterPro; IPR002720; RB_A.
DR   InterPro; IPR002719; RB_B.
DR   InterPro; IPR028309; RB_fam.
DR   InterPro; IPR024599; RB_N.
DR   PANTHER; PTHR13742; RETINOBLASTOMA-ASSOCIATED PROTEIN RB -RELATED; 1.
DR   PANTHER; PTHR13742:SF22; RETINOBLASTOMA-RELATED PROTEIN 2; 1.
DR   Pfam; PF11934; DUF3452; 1.
DR   Pfam; PF01858; RB_A; 1.
DR   Pfam; PF01857; RB_B; 1.
DR   SMART; SM01367; DUF3452; 1.
DR   SMART; SM01368; RB_A; 1.
DR   SUPFAM; SSF47954; Cyclin-like; 2.
PE   3: Inferred from homology;
KW   Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Repressor {ECO:0000256|ARBA:ARBA00022491};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          2..96
FT                   /note="Retinoblastoma-associated protein N-terminal"
FT                   /evidence="ECO:0000259|SMART:SM01367"
FT   DOMAIN          274..475
FT                   /note="Retinoblastoma-associated protein A-box"
FT                   /evidence="ECO:0000259|SMART:SM01368"
SQ   SEQUENCE   788 AA;  88312 MW;  9F80CCCB62F2B838 CRC64;
     MSSQDPPPAT STQKKQSESL VNLLAEASRF YRKAYNELFS GLITEWEPES STNTPDYMLF
     GWHLFLTLRS RSPELFKDLV SCIHGLVAVL AILLVHVPAK FRTFTIEGSS HLIKQTEKGV
     DLIASLCHNY HTSEECLKEM MDKSHKAIEE VFSMKALSAS ECKTENLDKI DTDRLMYFKG
     LIDMECFQSN LEKMEKLCNS NNCEAELDFK LILTNNDYIP CAENLSRDST NLGCSKCAFE
     TLASPTKTIK NMLTVPSSPL SPTNGGSVKI VQMTPITSAM TTAKWLREVI SSLPEKPSSK
     LQQLMSSCDR DLTNAVTERV SIVLEAIFPT KSSADRGGSL GLNCANAFDT LWADARKMEA
     SKLYYRVLEA ICRAELQNSN VNNLTPLLSN ERFHRCLIAC SAELVLATHK TVIMMFPAVL
     ESTGLTSFDL SKIIENFVRH EETLPRELKR HLNSLEEQIL ESMAWEKGSS LYNSLIVARP
     SVASEINRFG LLAESMPSLD DLVARQNIHI EGLPATPSKK RAAGRDDNAD PRSPKRPCNE
     SRSTVVEHNL QTPPPKQCHM VLTSLKAKCH PLQSTFASPT VSNPVGGNEK CADVTIQIFF
     SKILKLAAIR IRNLCERIQY MEQTERVYNV FKQILDQQTT LFFNRHIDQL ILCCLYGVAK
     VCQLELSFRE ILNNYKKEAQ CKPEVFLSIY IGSRNHNGVL ISRHVDIITF YNEVFVPAAK
     PFLVSLISSG TRPEDKKNAS GQVPGSPKLS PFPNLPDMSP KKVSASHNVY VSPLRQTKVF
     FCCNLFED
//