ID   A0A1D6QIX2_MAIZE        Unreviewed;       956 AA.
AC   A0A1D6QIX2;
DT   30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2016, sequence version 1.
DT   03-MAY-2023, entry version 34.
DE   SubName: Full=Retinoblastoma-related protein 1 {ECO:0000313|EMBL:AQK57744.1};
DE   Flags: Fragment;
GN   ORFNames=ZEAMMB73_Zm00001d052695 {ECO:0000313|EMBL:AQK57744.1};
OS   Zea mays (Maize).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC   Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX   NCBI_TaxID=4577 {ECO:0000313|EMBL:AQK57744.1};
RN   [1] {ECO:0000313|EMBL:AQK57744.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Seedling {ECO:0000313|EMBL:AQK57744.1};
RG   Maize Genome Sequencing Project;
RA   Ware D.;
RT   "Update maize B73 reference genome by single molecule sequencing
RT   technologies.";
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Regulator of biological processes that recruits a histone
CC       deacetylase to control gene transcription. May play a role in the entry
CC       into mitosis, negatively regulating the cell proliferation. Formation
CC       of stable complexes with geminiviridae replication-associated proteins
CC       may create a cellular environment which favors viral DNA replication.
CC       {ECO:0000256|ARBA:ARBA00025018}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the retinoblastoma protein (RB) family.
CC       {ECO:0000256|ARBA:ARBA00009475}.
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DR   EMBL; CM000780; AQK57744.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1D6QIX2; -.
DR   ExpressionAtlas; A0A1D6QIX2; baseline and differential.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051726; P:regulation of cell cycle; IEA:InterPro.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR   Gene3D; 1.10.472.140; -; 1.
DR   Gene3D; 1.10.472.10; Cyclin-like; 2.
DR   InterPro; IPR013763; Cyclin-like_dom.
DR   InterPro; IPR036915; Cyclin-like_sf.
DR   InterPro; IPR002720; RB_A.
DR   InterPro; IPR002719; RB_B.
DR   InterPro; IPR028309; RB_fam.
DR   InterPro; IPR024599; RB_N.
DR   PANTHER; PTHR13742:SF17; RETINOBLASTOMA-ASSOCIATED PROTEIN; 1.
DR   PANTHER; PTHR13742; RETINOBLASTOMA-ASSOCIATED PROTEIN RB -RELATED; 1.
DR   Pfam; PF11934; DUF3452; 1.
DR   Pfam; PF01858; RB_A; 1.
DR   Pfam; PF01857; RB_B; 1.
DR   SMART; SM00385; CYCLIN; 1.
DR   SMART; SM01367; DUF3452; 1.
DR   SMART; SM01368; RB_A; 1.
DR   SUPFAM; SSF47954; Cyclin-like; 2.
PE   3: Inferred from homology;
KW   Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Repressor {ECO:0000256|ARBA:ARBA00022491};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          89..231
FT                   /note="Retinoblastoma-associated protein N-terminal"
FT                   /evidence="ECO:0000259|SMART:SM01367"
FT   DOMAIN          415..615
FT                   /note="Retinoblastoma-associated protein A-box"
FT                   /evidence="ECO:0000259|SMART:SM01368"
FT   DOMAIN          743..861
FT                   /note="Cyclin-like"
FT                   /evidence="ECO:0000259|SMART:SM00385"
FT   REGION          866..885
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         956
FT                   /evidence="ECO:0000313|EMBL:AQK57744.1"
SQ   SEQUENCE   956 AA;  106431 MW;  54DA681D4208E462 CRC64;
     MDGVAKPSTS SGSGVTDSAS AAAASIDERF ADLCESKLGL DDSMTRQAMQ LFNETKNIKS
     SMSSLGGGSP EEVERFWSAC VMYCVSRLSK ARRSKESGSV SLCQILRASK LNIVDFFKEM
     PQFCIKVAHI LTGLYGSDWE KRLELKELQA NVVHLSLLSR HYKRAYQELF LPNDGKCSDS
     SSESNNQEVS DYYRFGWLLF LVLRIQTFSR FKDLVTSTNE LVSVLAVLII HIPVRLRNFD
     IKDSSYFGKK SDRGVSLIAS LCEKYHTSED ELSKALEKTN TLILDILKKK PWTATSACQQ
     DNLTFIDPEG LTVFKDLLQG GSLKSSLLIL EKEYENAINT RGELDERMFA NDEDSLLGSG
     SLSGGAINLP GTKRKYDVMA SPAKSISSPN PMSPPRFCLS PKGNSFCNSK MAPITPVSTA
     MTTAKWLRST VSPLPSKPSG ELLRFFSACD KDVTDDIVHR AGIILGAIFT SSSFGEQICT
     NMRSANRMDA IWTEQRKMEA LKLYYRVLES MCRAESQILS GNNLTLLLSN ERFHRCMIAC
     SAELVLATHK TVTLMFPAVL EKTGITAFDL SKVIEGFVRH EDTLPRELKR HLNSLEERLL
     ESMSWEKGSS MYNSLIVARP VLSIEINRLG LLAEPMPSLD AIAAHHNISM GGLPPLPFQK
     QERLQDKDEI RSPKRACTER RHVPVDSNSF RSQVKDSIKL KLPPPLQSAF ASPTRPNPAA
     GGETCAETGI AVFFSKISKL AAIRIRSLCE RLQLSQQVLE RVYSLVQQIL SQQTGLFFNR
     HIDQIILCSI YGVAKISQLQ LSFKEIVFGY RKQPQCKPQV FRSVYVHWPP TSHNGKTGED
     HVDIITFYNE VFIPAVKPLL VEVGPGASPK RKEEGKGSVY GPYPESPRLA RFPNLPDMSP
     KKVSATHNVY VSPLRSSKMD TLLSPSPKSY YACVGESTYA FQSPSKDLKA INNRLN
//