ID A0A1D6Y7D5_9VIRU Unreviewed; 439 AA.
AC A0A1D6Y7D5;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Papain-like cysteine peptidase {ECO:0000313|EMBL:ALX27567.1};
GN ORFNames=GMAR_ORF193 {ECO:0000313|EMBL:ALX27567.1};
OS Golden Marseillevirus.
OC Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Megaviricetes;
OC Pimascovirales; Marseilleviridae; Marseillevirus.
OX NCBI_TaxID=1720526 {ECO:0000313|EMBL:ALX27567.1, ECO:0000313|Proteomes:UP000203012};
RN [1] {ECO:0000313|EMBL:ALX27567.1, ECO:0000313|Proteomes:UP000203012}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Golden {ECO:0000313|EMBL:ALX27567.1,
RC ECO:0000313|Proteomes:UP000203012};
RX PubMed=27739526; DOI=10.1038/srep35237;
RA Dos Santos R.N., Campos F.S., Medeiros de Albuquerque N.R., Finoketti F.,
RA Correa R.A., Cano-Ortiz L., Assis F.L., Arantes T.S., Roehe P.M.,
RA Franco A.C.;
RT "A new marseillevirus isolated in Southern Brazil from Limnoperna
RT fortunei.";
RL Sci. Rep. 6:35237-35237(2016).
CC -!- SIMILARITY: Belongs to the peptidase C1 family.
CC {ECO:0000256|ARBA:ARBA00008455}.
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DR EMBL; KT835053; ALX27567.1; -; Genomic_DNA.
DR RefSeq; YP_009310310.1; NC_031465.1.
DR GeneID; 29674498; -.
DR KEGG; vg:29674498; -.
DR OrthoDB; 4752at10239; -.
DR Proteomes; UP000203012; Genome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008234; F:cysteine-type peptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR025661; Pept_asp_AS.
DR InterPro; IPR000169; Pept_cys_AS.
DR InterPro; IPR025660; Pept_his_AS.
DR InterPro; IPR013128; Peptidase_C1A.
DR InterPro; IPR000668; Peptidase_C1A_C.
DR PANTHER; PTHR12411:SF741; CATHEPSIN K; 1.
DR PANTHER; PTHR12411; CYSTEINE PROTEASE FAMILY C1-RELATED; 1.
DR Pfam; PF00112; Peptidase_C1; 1.
DR PRINTS; PR00705; PAPAIN.
DR SMART; SM00645; Pept_C1; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR PROSITE; PS51450; LRR; 1.
DR PROSITE; PS00640; THIOL_PROTEASE_ASN; 1.
DR PROSITE; PS00139; THIOL_PROTEASE_CYS; 1.
DR PROSITE; PS00639; THIOL_PROTEASE_HIS; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000203012};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 414..435
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 46..315
FT /note="Peptidase C1A papain C-terminal"
FT /evidence="ECO:0000259|SMART:SM00645"
SQ SEQUENCE 439 AA; 50262 MW; 0C49F02A2A4B0841 CRC64;
MELTKFATEA PRPSFTILRD QSKSVEEYYQ STNPKTSSLE ALEKFLPKFF DGRKKWNGLL
SRPLNQGNCG ACWSFSSTSC LADRFAILSN GQVKFAASPT KPIVCDFHPS VQDLSSQRKI
RELNEKFIKD GACHGNSLPE SFEYLYVYGT TTLGCFPYTF ANYTSSEQLP FCVDLVGKGF
DHCPTGVPMR IYRVKMPYFV QRKERRDTTD RDLMAEIYQR GPVSCGYVVY KDFMFPKDFP
KSWEEGVYKH DPAVTEVMGG HAIVVVGWGE TKKGKEYWII RNSWGEDWGD GGYFLMQRNC
QHLNLEQNNM TCIPDIPGLE LPEELQERYL NSNFHKALRQ TFPLHESGFP MSFVSQLTDE
QKSWLKPLVD KSLLPNLKTF IAGKMENPLE IPGAESDPNE SFEFSGQENR ERSWILLLVF
LAIAVFVAVL FLLTLTKKR
//
