ID A0A1D7NGT1_9SPHN Unreviewed; 598 AA.
AC A0A1D7NGT1;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN ORFNames=BG023_1121 {ECO:0000313|EMBL:AOL92980.1};
OS Porphyrobacter sp. LM 6.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Erythrobacteraceae; Erythrobacter/Porphyrobacter group; Porphyrobacter.
OX NCBI_TaxID=1896196 {ECO:0000313|EMBL:AOL92980.1, ECO:0000313|Proteomes:UP000094080};
RN [1] {ECO:0000313|EMBL:AOL92980.1, ECO:0000313|Proteomes:UP000094080}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LM 6 {ECO:0000313|EMBL:AOL92980.1,
RC ECO:0000313|Proteomes:UP000094080};
RA Hentchel K., Vargas G., Fiebig A., Coleman M., Crosson S.;
RT "Genome sequences of bacteria isolated from the littoral zone of southern
RT Lake Michigan.";
RL Submitted (AUG-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- SIMILARITY: Belongs to the helicase family. RecQ subfamily.
CC {ECO:0000256|ARBA:ARBA00005446}.
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DR EMBL; CP017113; AOL92980.1; -; Genomic_DNA.
DR RefSeq; WP_069308644.1; NZ_CP017113.1.
DR AlphaFoldDB; A0A1D7NGT1; -.
DR STRING; 1896196.BG023_1121; -.
DR KEGG; porl:BG023_1121; -.
DR PATRIC; fig|1896196.3.peg.22; -.
DR OrthoDB; 9760034at2; -.
DR Proteomes; UP000094080; Chromosome.
DR GO; GO:0043138; F:3'-5' DNA helicase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR GO; GO:0009432; P:SOS response; IEA:InterPro.
DR CDD; cd17920; DEXHc_RecQ; 1.
DR CDD; cd18794; SF2_C_RecQ; 1.
DR Gene3D; 1.10.150.80; HRDC domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR004589; DNA_helicase_ATP-dep_RecQ.
DR InterPro; IPR006293; DNA_helicase_ATP-dep_RecQ_bac.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR010997; HRDC-like_sf.
DR InterPro; IPR002121; HRDC_dom.
DR InterPro; IPR044876; HRDC_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR032284; RecQ_Zn-bd.
DR InterPro; IPR018982; RQC_domain.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR NCBIfam; TIGR01389; recQ; 1.
DR NCBIfam; TIGR00614; recQ_fam; 1.
DR PANTHER; PTHR13710:SF105; BLOOM SYNDROME PROTEIN; 1.
DR PANTHER; PTHR13710; DNA HELICASE RECQ FAMILY MEMBER; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF00570; HRDC; 1.
DR Pfam; PF16124; RecQ_Zn_bind; 1.
DR Pfam; PF09382; RQC; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00341; HRDC; 1.
DR SMART; SM00956; RQC; 1.
DR SUPFAM; SSF47819; HRDC-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS50967; HRDC; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:AOL92980.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 30..196
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 220..364
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 522..598
FT /note="HRDC"
FT /evidence="ECO:0000259|PROSITE:PS50967"
SQ SEQUENCE 598 AA; 64864 MW; FD05332ED0144D58 CRC64;
MHAPLAPDLH EILRRTFGYQ DFRGQQEAVI GRIMRGAHTL ALMPTGAGKS LCYQIPALAR
PGTAIVISPL IALMHDQIRS ATAAGIRAAS MTSADSDNAA TAEAFRAGAL DLLYVAPERA
STVGFQNLLE RAEIALFAID EAHCVSEWGH DFRPDYRALK PVLDRFPDVP RLALTATADP
ATRADILRQL GIAEDGLIIA GFDRPNIRYT ITPRDSGPRQ IAELLQRLDG AGIVYAPSRK
QAEDLADHIA RSGRRAGYYH AGLDPERRAS VQAEFVASED MVMVATIAFG MGIDKPDVRF
VIHAGLPKSI EAYYQETGRA GRDGDPAEAH LLWGVSDFAR ARQWLAEVEP ERLAAEQARL
NALAGLVETP DCRRAVLLRY FGEQPPATCG NCDNCENPPQ VVDASELARK LLSAVYRTGQ
SFGLGHIEKV LTGQSDDRVE SRAHDKLSVF GIVGSEEAPM LRPLARTLVA RGMLAATEHG
GLMLGPEARA VLKGEAGVMM AEPPVRQRRG RRVRGGANDA PNPVGNPLFE ALRAKRKDLA
SEHGIPAYVI FHDSVLRDMA HQCPETLAEL GTISGVGAKK LETWGPDFIA VVREHLRG
//
