ID A0A1D7VNA4_9ACTN Unreviewed; 852 AA.
AC A0A1D7VNA4;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=UvrABC system protein A {ECO:0000256|ARBA:ARBA00039316};
DE AltName: Full=Excinuclease ABC subunit A {ECO:0000256|ARBA:ARBA00042156};
GN ORFNames=SL103_20240 {ECO:0000313|EMBL:AOP48249.1};
OS Streptomyces lydicus.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=47763 {ECO:0000313|EMBL:AOP48249.1, ECO:0000313|Proteomes:UP000094094};
RN [1] {ECO:0000313|EMBL:AOP48249.1, ECO:0000313|Proteomes:UP000094094}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=103 {ECO:0000313|EMBL:AOP48249.1,
RC ECO:0000313|Proteomes:UP000094094};
RA Jia N., Ding M.-Z., Gao F., Yuan Y.-J.;
RT "Complete genome sequencing of Streptomyces lydicus 103 and metabolic
RT pathways analysis of antibiotic biosynthesis.";
RL Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. UvrA family.
CC {ECO:0000256|ARBA:ARBA00038000}.
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DR EMBL; CP017157; AOP48249.1; -; Genomic_DNA.
DR RefSeq; WP_069570385.1; NZ_CP017157.1.
DR AlphaFoldDB; A0A1D7VNA4; -.
DR KEGG; slc:SL103_20240; -.
DR OrthoDB; 9809851at2; -.
DR Proteomes; UP000094094; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0009380; C:excinuclease repair complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR Gene3D; 1.10.8.280; ABC transporter ATPase domain-like; 1.
DR Gene3D; 1.20.1580.10; ABC transporter ATPase like domain; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR004602; UvrA.
DR InterPro; IPR041552; UvrA_DNA-bd.
DR NCBIfam; TIGR00630; uvra; 1.
DR PANTHER; PTHR43152; UVRABC SYSTEM PROTEIN A; 1.
DR PANTHER; PTHR43152:SF3; UVRABC SYSTEM PROTEIN A; 1.
DR Pfam; PF17755; UvrA_DNA-bind; 1.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 3.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA excision {ECO:0000256|ARBA:ARBA00022769};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Excision nuclease {ECO:0000256|ARBA:ARBA00022881};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000094094};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 499..836
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 852 AA; 90632 MW; C19FD3A9FCC89210 CRC64;
MVALIHIKGA RLHNLKNVTL DLPKNKLVVL TGLSGSGKST LALDTLHREG QRQYLESLGM
VTGFVSKPAV DAITGLSPSI GVDQHLTNRS PRSTVGTATE VFTYLRVLWA RIGHRPCPGC
GHLLPPSYRV GGEQIQDDDA DAAGPALPCP RCATPVPELV MGDFSFNKPA GACPACTGLG
VTVRADVHRL VDHDRGVADG AVLGWHPTVT ERILPTLHAA ARHYGFTFDD RLPVRDLPDA
PRALLLHGVD SPQFRRHFPD TAPPATVARG RFEGVVTATL RRYAQRIDDT AYREKAERSL
LQETCPDCRG TRLRPESRCV TVAGLTLVDA ARLPLDALAG WLDALRGRVT AEEWLLTEPV
VADLHERVRR LVDVGVGYLT AEQPTPSLSA GEAQRLRLAA LLGSGLTGVL YVLDEPTIGL
HPADSARLIE VLCRLRDLGN TVLVIEHDLD VLRAADHVVD VGPGAGRDGG RIVAQGTPAE
VAANPESVTG AYLAGRLAVP VPETPRPGDG RALVIRGARA HHLKDLTVRL PLGQLVAVTG
PSGSGKSSLL LDILGRAARR HFHGAGEPPA EHDGIDGWEH LDKVVTIDQQ PISRLPRSNA
ATYSDAFTPI REAFARTAAA RERGLTPGHF SANVPGGRCE RCEGAGVLAV PMHFLPAVEV
RCPACRGSRF RPEVCEVRHG GHDIAQVLDA TVDEALAVFA DLPAVANRLQ RLADVGLGYL
QLGQPATTLS GGEAQRVKLA RELGRRTTGR TLYLLDEPTT GLHAADTARL LGVLQRLVDA
GHTVVTIEHN LDVIRAADWV VDLGPAGGAA GGTVVAEGTP KEIAGAAGSR TGAFLQWATP
RPHTAVARGI SR
//
