ID   A0A1D7XI72_9CLOT        Unreviewed;       475 AA.
AC   A0A1D7XI72;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   24-JAN-2024, entry version 27.
DE   SubName: Full=Sodium:alanine symporter family protein {ECO:0000313|EMBL:AOR23035.1};
GN   ORFNames=BGI42_04570 {ECO:0000313|EMBL:AOR23035.1};
OS   Clostridium taeniosporum.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=394958 {ECO:0000313|EMBL:AOR23035.1, ECO:0000313|Proteomes:UP000094652};
RN   [1] {ECO:0000313|Proteomes:UP000094652}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1/k {ECO:0000313|Proteomes:UP000094652};
RA   Walker J.R.;
RT   "Genomics of Clostridium taeniosporum, an organism which forms endospores
RT   with ribbon-like appendages.";
RL   Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU363064};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU363064}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the alanine or glycine:cation symporter (AGCS)
CC       (TC 2.A.25) family. {ECO:0000256|ARBA:ARBA00009261,
CC       ECO:0000256|RuleBase:RU363064}.
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DR   EMBL; CP017253; AOR23035.1; -; Genomic_DNA.
DR   RefSeq; WP_069679190.1; NZ_CP017253.2.
DR   AlphaFoldDB; A0A1D7XI72; -.
DR   STRING; 394958.BGI42_04570; -.
DR   KEGG; ctae:BGI42_04570; -.
DR   OrthoDB; 9804874at2; -.
DR   Proteomes; UP000094652; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005283; F:amino acid:sodium symporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR   InterPro; IPR001463; Na/Ala_symport.
DR   NCBIfam; TIGR00835; agcS; 1.
DR   PANTHER; PTHR30330; AGSS FAMILY TRANSPORTER, SODIUM-ALANINE; 1.
DR   PANTHER; PTHR30330:SF3; TRANSCRIPTIONAL REGULATOR, LRP FAMILY-RELATED; 1.
DR   Pfam; PF01235; Na_Ala_symp; 1.
DR   PRINTS; PR00175; NAALASMPORT.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|RuleBase:RU363064};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363064};
KW   Reference proteome {ECO:0000313|Proteomes:UP000094652};
KW   Symport {ECO:0000256|RuleBase:RU363064};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU363064};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU363064};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU363064}.
FT   TRANSMEM        25..42
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        78..101
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        107..125
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        158..181
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        193..212
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        224..243
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        263..281
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        312..335
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        371..391
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        411..431
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
SQ   SEQUENCE   475 AA;  50484 MW;  09F67DB8193150B3 CRC64;
     MLLSNLLLST AGVQSFLKTI DSIIWGPPLL ILLVGTGLYL TFRLKVLQIF RLPMALKFVF
     GKDDELKNED AKGDVSSFAA LCTALSATIG TGNIVGVATA IKAGGPGALL WMWLAAFFGM
     ATKYAEGVLA IKYREIDENG EMCGGPMYYI QNGLGLKWLA KLFALFGVGV AFFGIGTFGQ
     VNSIAAAASN FNIPLYATAI VTTTLVALVT LGGIKRISKV SETFVPFMAV AYIIGAALVL
     IFNHTAVPGA IRLVFESAFN TEAIGGGVLG ITVTMAIRNG IARGVFSNES GLGSAPIAAA
     AAKTNLPVKQ GLISMTGTFF DTIIVCTMTG LAIVITSGST GVFEVGATIE GAGLTSAAFE
     IGLPIAFLGK YIVNIGLIFF AFTTILGWNY YGEKCIQYLF GTKLIMPYRI IYIMLVAIGP
     FLPLELIFII ADIVNGCMAF PNLIGLIGLR KVIIQETEEF FEEMKEKDSM EEAVV
//