ID A0A1D7Y6A4_9ACTN Unreviewed; 625 AA.
AC A0A1D7Y6A4;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE RecName: Full=exo-alpha-sialidase {ECO:0000256|ARBA:ARBA00012733};
DE EC=3.2.1.18 {ECO:0000256|ARBA:ARBA00012733};
GN ORFNames=BFF78_08635 {ECO:0000313|EMBL:AOR31101.1};
OS Streptomyces fodineus.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1904616 {ECO:0000313|EMBL:AOR31101.1, ECO:0000313|Proteomes:UP000094960};
RN [1] {ECO:0000313|Proteomes:UP000094960}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TW1S1 {ECO:0000313|Proteomes:UP000094960};
RA Kim M.-K., Kim S.B.;
RT "Streptomyces puniciscabiei strain:TW1S1 Genome sequencing and assembly.";
RL Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 33 family.
CC {ECO:0000256|ARBA:ARBA00009348}.
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DR EMBL; CP017248; AOR31101.1; -; Genomic_DNA.
DR RefSeq; WP_069777749.1; NZ_CP017248.1.
DR AlphaFoldDB; A0A1D7Y6A4; -.
DR KEGG; spun:BFF78_08635; -.
DR Proteomes; UP000094960; Chromosome.
DR GO; GO:0004308; F:exo-alpha-sialidase activity; IEA:InterPro.
DR CDD; cd00110; LamG; 1.
DR CDD; cd15482; Sialidase_non-viral; 1.
DR Gene3D; 2.120.10.10; -; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR006558; LamG-like.
DR InterPro; IPR001791; Laminin_G.
DR InterPro; IPR011040; Sialidase.
DR InterPro; IPR026856; Sialidase_fam.
DR InterPro; IPR036278; Sialidase_sf.
DR PANTHER; PTHR10628; SIALIDASE; 1.
DR PANTHER; PTHR10628:SF25; SIALIDASE-1; 1.
DR Pfam; PF13088; BNR_2; 1.
DR Pfam; PF13385; Laminin_G_3; 1.
DR SMART; SM00282; LamG; 1.
DR SMART; SM00560; LamGL; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF50939; Sialidases; 1.
PE 3: Inferred from homology;
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..35
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 36..625
FT /note="exo-alpha-sialidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5009102609"
FT DOMAIN 461..600
FT /note="LamG-like jellyroll fold"
FT /evidence="ECO:0000259|SMART:SM00560"
FT DOMAIN 461..595
FT /note="Laminin G"
FT /evidence="ECO:0000259|SMART:SM00282"
FT REGION 273..294
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 625 AA; 67490 MW; CEF431B2D9D10E1F CRC64;
MPSGLRARLR SALATALSTA ALLLAPLATP QAAHAQPTSA SPKFEQQVLF KAAQDPGYAC
FRIPAIVKTA DGTLLAFAEG RVLNCGDAAD IDIVLKRSTD GGRTWGPLQV VNDGGGDTHG
NPAPIVDRAT GRVWLAETYN TGRTDSASCS IPCDRTPHLQ YSDDDGATWS APRDLSPEIL
PADWNSWYAT GPVHGIQLTK GRYAGRLVFG VNTETWDGGR VTANHAALIV SDDHGGHWRI
GATDTWPIAD DGTFRQKPSE LALAERGDGS LLVSGREQDG TDLGHRTQAV SRDGGSSFTA
TFHDLPDLYA PQVQGSLLRL GNRLLLACPA DPDRRRTMMI RSSYDGGRTW DSVDRGTVVT
TDWSGYSDLV RVDADTVGLI YEGGAVDARG EIRFARFTED WLAPRRGPDP VTADLAPHAR
PAAVLGGAEE TEGVFGGALR FDGSDDAVRL PYRSALPLGR KDFTASLWFR YTATTGEQPL
LWMGGVGTSQ PQVWVRGEPS NHRIQGLITV RDGAIAPQTA YVRTNTAYND GEWHHLVLRR
GEGRLSLFVD GMQSSVDDIP GSVSRNSPFG VHIGQRMDSR AFFTGAIDEV HVWDRALTDQ
ELSDPKALRS PKDTVLWLPL DHVSG
//
