ID A0A1D8AZ69_9BACT Unreviewed; 806 AA.
AC A0A1D8AZ69;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Macrolide export ATP-binding/permease protein MacB {ECO:0000313|EMBL:AOS46190.1};
DE EC=3.6.3.- {ECO:0000313|EMBL:AOS46190.1};
GN Name=macB_20 {ECO:0000313|EMBL:AOS46190.1};
GN ORFNames=Verru16b_03287 {ECO:0000313|EMBL:AOS46190.1};
OS Lacunisphaera limnophila.
OC Bacteria; Verrucomicrobiota; Opitutae; Opitutales; Opitutaceae;
OC Lacunisphaera.
OX NCBI_TaxID=1838286 {ECO:0000313|EMBL:AOS46190.1, ECO:0000313|Proteomes:UP000095228};
RN [1] {ECO:0000313|EMBL:AOS46190.1, ECO:0000313|Proteomes:UP000095228}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IG16b {ECO:0000313|EMBL:AOS46190.1,
RC ECO:0000313|Proteomes:UP000095228};
RA Rast P., Gloeckner I., Jogler M., Boedeker C., Jeske O., Wiegand S.,
RA Reinhardt R., Schumann P., Rohde M., Spring S., Gloeckner F.O., Jogler C.;
RT "Three novel species with peptidoglycan cell walls form the new genus
RT Lacunisphaera gen. nov. in the family Opitutaceae of the verrucomicrobial
RT subdivision 4.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the ABC-4 integral membrane protein family.
CC {ECO:0000256|ARBA:ARBA00038076}.
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DR EMBL; CP016094; AOS46190.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1D8AZ69; -.
DR STRING; 1838286.Verru16b_03287; -.
DR KEGG; obg:Verru16b_03287; -.
DR Proteomes; UP000095228; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR InterPro; IPR003838; ABC3_permease_dom.
DR InterPro; IPR017800; ADOP.
DR InterPro; IPR025857; MacB_PCD.
DR NCBIfam; TIGR03434; ADOP; 1.
DR PANTHER; PTHR30572:SF4; MACROLIDE EXPORT ATP-BINDING_PERMEASE PROTEIN MACB; 1.
DR PANTHER; PTHR30572; MEMBRANE COMPONENT OF TRANSPORTER-RELATED; 1.
DR Pfam; PF02687; FtsX; 2.
DR Pfam; PF12704; MacB_PCD; 2.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000313|EMBL:AOS46190.1};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Hydrolase {ECO:0000313|EMBL:AOS46190.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000313|EMBL:AOS46190.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000095228};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..45
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 270..292
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 326..348
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 368..390
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 418..438
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 683..708
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 738..757
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 769..791
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 19..232
FT /note="MacB-like periplasmic core"
FT /evidence="ECO:0000259|Pfam:PF12704"
FT DOMAIN 277..394
FT /note="ABC3 transporter permease protein"
FT /evidence="ECO:0000259|Pfam:PF02687"
FT DOMAIN 424..639
FT /note="MacB-like periplasmic core"
FT /evidence="ECO:0000259|Pfam:PF12704"
FT DOMAIN 686..799
FT /note="ABC3 transporter permease protein"
FT /evidence="ECO:0000259|Pfam:PF02687"
SQ SEQUENCE 806 AA; 86236 MW; FCC34CB9B8BB966B CRC64;
MISELKFAVR QLLKSPGFTA IALLTLTLGI GVNTAMFTVV NTLLFQPAPY PDSAQVVRVY
GTNAQGDAWP HSLPDLRDLG TQGQTFASVT PYQWWIFSLA EPGQPAEALN GVVAAANLFD
TLGLQPVLGR AFTAEEQQAG RDTVAVLSDA CWRRKFGADP GIIGRSLRIG GESVTIIGVM
PAQAEYPTFW GPIDVWRPLP LAEGWREDRS VSWLQAVARL KPGVSRTEAQ AESTVIAGRL
ALQYPGSNAG KGVRLVPLVG SEVAVVHRRL IWLTLGLAGF VLLIACANLG NLQLARSAGR
ARDFAIRAAL GASRPALMRR LLVENLLLGL AGGGLGLLAA QFLTSFLAPH LFAGKTANAV
FQTDGRVFAF ALGVAVLAGL LSGGIPAWLA SRTDVNLALK QQSRGATGDR GRQRGRQALI
VSQIAFSVVL LAGSAFFLRG LQRYLTQDPG WRVEGLVRGT MTLTELKYPT EASRRLFHQR
LMERVARLPG VEGAALTVSL PLRDYTTPMG FVPEGREEPR PGHEPFAFHN IVSADYFSLL
GIRLVEGRAF APAEPPAGSP HQIIISESIA RQFWPGESAI GRRIREVDPQ GRPHWEVIGV
VRDVGLAGNV DTPATHYQIY HNMAQNPWGY FTLVARSRNP ATLADPLRRA VAELDPDLPV
VELRTVQETV AGALHDLQVT NKLLAAFAGL GLCLAALGIY GVISGLVAMR IQEFGIRLAL
GAQPEHVLRI VLGNGVRLAG LGTALGLGLA ALLLPSLSAA FPGLPGLDVP AFLAVVALLL
AVTLVACWLP ARRATKVDPM VALRAE
//
