ID A0A1D8BZ43_9PSEU Unreviewed; 494 AA.
AC A0A1D8BZ43;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE RecName: Full=Probable malate:quinone oxidoreductase {ECO:0000256|HAMAP-Rule:MF_00212};
DE EC=1.1.5.4 {ECO:0000256|HAMAP-Rule:MF_00212};
DE AltName: Full=MQO {ECO:0000256|HAMAP-Rule:MF_00212};
DE AltName: Full=Malate dehydrogenase [quinone] {ECO:0000256|HAMAP-Rule:MF_00212};
GN Name=mqo {ECO:0000256|HAMAP-Rule:MF_00212};
GN ORFNames=BKA25_002222 {ECO:0000313|EMBL:MBB5907906.1};
OS Actinoalloteichus hymeniacidonis.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Actinoalloteichus.
OX NCBI_TaxID=340345 {ECO:0000313|EMBL:MBB5907906.1, ECO:0000313|Proteomes:UP000551592};
RN [1] {ECO:0000313|EMBL:MBB5907906.1, ECO:0000313|Proteomes:UP000551592}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 45092 {ECO:0000313|EMBL:MBB5907906.1,
RC ECO:0000313|Proteomes:UP000551592};
RA Klenk H.-P.;
RT "Sequencing the genomes of 1000 actinobacteria strains.";
RL Submitted (AUG-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=(S)-malate + a quinone = a quinol + oxaloacetate;
CC Xref=Rhea:RHEA:46012, ChEBI:CHEBI:15589, ChEBI:CHEBI:16452,
CC ChEBI:CHEBI:24646, ChEBI:CHEBI:132124; EC=1.1.5.4;
CC Evidence={ECO:0000256|ARBA:ARBA00001139, ECO:0000256|HAMAP-
CC Rule:MF_00212};
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974,
CC ECO:0000256|HAMAP-Rule:MF_00212};
CC -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle;
CC oxaloacetate from (S)-malate (quinone route): step 1/1.
CC {ECO:0000256|ARBA:ARBA00005012, ECO:0000256|HAMAP-Rule:MF_00212}.
CC -!- SIMILARITY: Belongs to the MQO family. {ECO:0000256|HAMAP-
CC Rule:MF_00212}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:MBB5907906.1}.
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DR EMBL; JACHIS010000001; MBB5907906.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1D8BZ43; -.
DR STRING; 340345.TL08_16160; -.
DR UniPathway; UPA00223; UER01008.
DR Proteomes; UP000551592; Unassembled WGS sequence.
DR GO; GO:0052589; F:malate dehydrogenase (menaquinone) activity; IEA:UniProtKB-EC.
DR GO; GO:0008924; F:malate dehydrogenase (quinone) activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniRule.
DR Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR HAMAP; MF_00212; MQO; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR006231; MQO.
DR NCBIfam; TIGR01320; mal_quin_oxido; 1.
DR PANTHER; PTHR43104; L-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43104:SF2; L-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR Pfam; PF06039; Mqo; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827, ECO:0000256|HAMAP-Rule:MF_00212};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630, ECO:0000256|HAMAP-
KW Rule:MF_00212};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002, ECO:0000256|HAMAP-
KW Rule:MF_00212}; Tricarboxylic acid cycle {ECO:0000256|HAMAP-Rule:MF_00212}.
SQ SEQUENCE 494 AA; 53250 MW; 8D221187777BDBF4 CRC64;
MVDTEIHDIV LVGAGIVSAT LGTLIATLQP DWRITVLERL GEPGNESSHA WNNAGTGHAG
LCEFNYTPRG SDGTVDATGA VRIGEQYLTS LCFWAELVAQ GQLGDPGDFI RSTPHLGLGR
GTDGVAYLRA RHAALREHPL FADLEISADR SRLEAWLPLV LRGRDEREPI AVTRSRQGTD
VDFGVLTRRL LAALQRRGVA VRTHHEVRSL RRGQGRWEIG VRDRRADRVE TLRSRFVFVG
AGGATLPLLQ GAGVPEVRGL GAFPISGRFL RASRPALVAE HPAKLYGHAA PGAPSISVPH
LDRRVVAGRE HLLFGPFAAF SPRFLKRGRH TDLVRSIRPD NLPTLLATAR DNPSLLAYLV
RQLTQSSAAR LAALREFVPT AQEADWKLIT AGQRVQTLRT VAGRGTMVGF GAEQLITEDA
TLAALLGASP GASASASAMV AVLAGCFPDR MPAWESRLRT LAPNASELLA TGQAIDRLAH
ARRTLGLDPL ISRS
//
