ID   A0A1D8G627_9ACTN        Unreviewed;       526 AA.
AC   A0A1D8G627;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Carboxylesterase A {ECO:0000313|EMBL:AOT60916.1};
DE            EC=3.1.1.- {ECO:0000313|EMBL:AOT60916.1};
GN   Name=caeA_2 {ECO:0000313|EMBL:AOT60916.1};
GN   ORFNames=A4G23_03791 {ECO:0000313|EMBL:AOT60916.1};
OS   Streptomyces rubrolavendulae.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=285473 {ECO:0000313|EMBL:AOT60916.1, ECO:0000313|Proteomes:UP000095349};
RN   [1] {ECO:0000313|EMBL:AOT60916.1, ECO:0000313|Proteomes:UP000095349}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MJM4426 {ECO:0000313|EMBL:AOT60916.1,
RC   ECO:0000313|Proteomes:UP000095349};
RA   Kim J.-G.;
RT   "Streptomyces rubrolavendulae MJM4426 Genome sequencing and assembly.";
RL   Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase S33 family.
CC       {ECO:0000256|ARBA:ARBA00010088}.
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DR   EMBL; CP017316; AOT60916.1; -; Genomic_DNA.
DR   RefSeq; WP_031129855.1; NZ_CP017316.1.
DR   AlphaFoldDB; A0A1D8G627; -.
DR   STRING; 285473.A4G23_03791; -.
DR   KEGG; srn:A4G23_03791; -.
DR   PATRIC; fig|285473.5.peg.3973; -.
DR   OrthoDB; 4498590at2; -.
DR   Proteomes; UP000095349; Chromosome.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR013595; Pept_S33_TAP-like_C.
DR   PANTHER; PTHR43248; 2-SUCCINYL-6-HYDROXY-2,4-CYCLOHEXADIENE-1-CARBOXYLATE SYNTHASE; 1.
DR   PANTHER; PTHR43248:SF29; AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF08386; Abhydrolase_4; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:AOT60916.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000095349};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           25..526
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5038477781"
FT   DOMAIN          420..524
FT                   /note="Peptidase S33 tripeptidyl aminopeptidase-like C-
FT                   terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08386"
FT   REGION          33..87
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   526 AA;  54667 MW;  5B0D6611119AFAAA CRC64;
     MTKRVRVRAV AAAATAALVA GVVAGCQGDG AAGSAGAGAA PSAGGAAPVR PGSSAGMPDL
     PAALTGQKPR WGACEAPEGG EDPGEGWRCA TVKVPLDYRE PDGETLAVAL IRKEAREKKG
     RIGSLLFNFG GPGASGVEML PGFAPGYEAL NARYDLVGFD PRGVGGSSAV VCRSDEEQAA
     AEKRIDLTPD TPAEEAAYLK DGADFGAGCA RRSGKLIPHV TTGNTARDMD VIRHVLGDDR
     LYYFGISYGT QLGAAYAHLF PKHTGRTVLD AVVDPTADSL GHARHQTTGF QRALNNYLAS
     TGEDAAEGTA RIARLLDRLD ERPLPTSGDR KLTEGLALTG IVLPLYSESS WPLLTEALRE
     AEGGRGDALL RLADMYNERD EDGRYGTDSH SQRAISCADT DQRPTAAEAK ALLPEFRRIS
     PVFGEFLAWD TAGWCANWPV KGEGGGQDVS APGAQPILVV GTTGDPATPY EGARKMADGL
     GKGVGVLVTN KGEGHGAYGT SGCVTRTVDD YLLRGKVPAD GTTCSS
//