ID A0A1D8G8Z7_9ACTN Unreviewed; 936 AA.
AC A0A1D8G8Z7;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Calcium-transporting ATPase {ECO:0000313|EMBL:AOT61912.1};
DE EC=3.6.3.8 {ECO:0000313|EMBL:AOT61912.1};
GN Name=yloB {ECO:0000313|EMBL:AOT61912.1};
GN ORFNames=A4G23_04803 {ECO:0000313|EMBL:AOT61912.1};
OS Streptomyces rubrolavendulae.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=285473 {ECO:0000313|EMBL:AOT61912.1, ECO:0000313|Proteomes:UP000095349};
RN [1] {ECO:0000313|EMBL:AOT61912.1, ECO:0000313|Proteomes:UP000095349}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MJM4426 {ECO:0000313|EMBL:AOT61912.1,
RC ECO:0000313|Proteomes:UP000095349};
RA Kim J.-G.;
RT "Streptomyces rubrolavendulae MJM4426 Genome sequencing and assembly.";
RL Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216;
CC Evidence={ECO:0000256|ARBA:ARBA00001836};
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP017316; AOT61912.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1D8G8Z7; -.
DR STRING; 285473.A4G23_04803; -.
DR KEGG; srn:A4G23_04803; -.
DR PATRIC; fig|285473.5.peg.5062; -.
DR OrthoDB; 9814270at2; -.
DR Proteomes; UP000095349; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR Gene3D; 3.40.1110.10; Calcium-transporting ATPase, cytoplasmic domain N; 1.
DR Gene3D; 2.70.150.10; Calcium-transporting ATPase, cytoplasmic transduction domain A; 1.
DR Gene3D; 1.20.1110.10; Calcium-transporting ATPase, transmembrane domain; 1.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR InterPro; IPR006068; ATPase_P-typ_cation-transptr_C.
DR InterPro; IPR004014; ATPase_P-typ_cation-transptr_N.
DR InterPro; IPR023299; ATPase_P-typ_cyto_dom_N.
DR InterPro; IPR018303; ATPase_P-typ_P_site.
DR InterPro; IPR023298; ATPase_P-typ_TM_dom_sf.
DR InterPro; IPR008250; ATPase_P-typ_transduc_dom_A_sf.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR023214; HAD_sf.
DR InterPro; IPR001757; P_typ_ATPase.
DR InterPro; IPR044492; P_typ_ATPase_HD_dom.
DR NCBIfam; TIGR01494; ATPase_P-type; 3.
DR PANTHER; PTHR42861; CALCIUM-TRANSPORTING ATPASE; 1.
DR PANTHER; PTHR42861:SF29; SECRETORY PATHWAY CALCIUM ATPASE, ISOFORM G; 1.
DR Pfam; PF13246; Cation_ATPase; 1.
DR Pfam; PF00689; Cation_ATPase_C; 1.
DR Pfam; PF00690; Cation_ATPase_N; 1.
DR Pfam; PF00122; E1-E2_ATPase; 1.
DR Pfam; PF00702; Hydrolase; 1.
DR PRINTS; PR00119; CATATPASE.
DR PRINTS; PR00121; NAKATPASE.
DR SFLD; SFLDS00003; Haloacid_Dehalogenase; 1.
DR SFLD; SFLDF00027; p-type_atpase; 1.
DR SMART; SM00831; Cation_ATPase_N; 1.
DR SUPFAM; SSF81653; Calcium ATPase, transduction domain A; 1.
DR SUPFAM; SSF81665; Calcium ATPase, transmembrane domain M; 1.
DR SUPFAM; SSF56784; HAD-like; 1.
DR SUPFAM; SSF81660; Metal cation-transporting ATPase, ATP-binding domain N; 1.
DR PROSITE; PS00154; ATPASE_E1_E2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Hydrolase {ECO:0000313|EMBL:AOT61912.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000095349};
KW Translocase {ECO:0000256|ARBA:ARBA00022967};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 79..97
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 103..119
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 271..288
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 300..322
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 802..822
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 867..886
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 898..918
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 25..99
FT /note="Cation-transporting P-type ATPase N-terminal"
FT /evidence="ECO:0000259|SMART:SM00831"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 533..556
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 936 AA; 97149 MW; DB4B3D88E3607DF7 CRC64;
MPRPTPTASG PGAAPGRTSR EPVAHAYRRG AAEVADLLGV DPAAGLSAAE ARRRAADWGA
NELAEPARRP QWLRLLDQFR SWLIGILLGA AVLAGIIGDL RDAVVITVVL LVNALIGFLQ
ERRAERSLEA LRRMLVPTAR VRRDGEVRTV PARELVPGDV VLLEAGDRVP ADGRLVVAES
VEVAEAALTG ESQPVAKTTA PAGAGDEAPV PVAERTGTLF MNTALTRGRA EMVVTATGMG
TEVGAIAEAL RTGGEPPSPL RVQMDSLGRR LALVSGVAVA AYALVALARG EDLADLALRA
VALAVAAIPE GLPAVLALTL ALGVHRMARR GAIVKRLASV EALGSATVVC SDKTGTLTLN
EMTARALWAA GRLYEVTGEG YGTDGAVRPA GPGDRGDAPP EPPREAVLPF ALCNDAALSP
GGGAVGDPTE AALLVLAAKA GLDPAAPRAR TPRTGEIPFD PAEKYMATFH TDADGGVRVH
VKGAVDVLLD RCTHVLTEDG PVPLTDERRA EITAVARRMG GEGLRVLGAA TATTAAPAAT
TAAPDATASD GRDRPHALPA TGLTLTAVAG IADPPRPQAH DAVALARAAG VTVKMITGDH
ADTATAIARE LGIDGDVVTG AELDRMSERD LADRIEDIGV FARVAPEHKV TIVRALSAGG
HIVAMTGDGV NDAAALRAAH IGVAMGITGT DVAKEAADVV LTDDDFSTIV RAVREGRSLY
DNIVTFVRFQ LSTNIGAILT LLAAVLTGLP TPMTAIQLLW VNIIMDGPPA MALGIDPPRG
DVMSRPPRPP SERILNHRRL TVIVRAGLVM TVGTLTVFAL ARRYTDEATA ATMAFTTFVL
FQLCNALAAR SEDGPVLGRF QLRNRTLWIC LGAVLVLQVV AVQVPFAQGV FDTVALSAAQ
WAVCLAAAST VLLAEQAWRT GRARSAHRRA GGRAGS
//
