ID A0A1D8GPD6_9CLOT Unreviewed; 453 AA.
AC A0A1D8GPD6;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Thioether cross-link-forming SCIFF peptide maturase {ECO:0000313|EMBL:AOT72820.1};
GN ORFNames=Gferi_26635 {ECO:0000313|EMBL:AOT72820.1};
OS Geosporobacter ferrireducens.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Geosporobacter.
OX NCBI_TaxID=1424294 {ECO:0000313|EMBL:AOT72820.1, ECO:0000313|Proteomes:UP000095743};
RN [1] {ECO:0000313|EMBL:AOT72820.1, ECO:0000313|Proteomes:UP000095743}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IRF9 {ECO:0000313|EMBL:AOT72820.1,
RC ECO:0000313|Proteomes:UP000095743};
RA Kim S.-J.;
RT "Genomic analysis reveals versatility of anaerobic energy metabolism of
RT Geosporobacter ferrireducens IRF9 of phylum Firmicutes.";
RL Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- SIMILARITY: Belongs to the radical SAM superfamily. Anaerobic
CC sulfatase-maturating enzyme family. {ECO:0000256|ARBA:ARBA00023601}.
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DR EMBL; CP017269; AOT72820.1; -; Genomic_DNA.
DR RefSeq; WP_069981129.1; NZ_VENK01000008.1.
DR AlphaFoldDB; A0A1D8GPD6; -.
DR STRING; 1424294.Gferi_26635; -.
DR KEGG; gfe:Gferi_26635; -.
DR OrthoDB; 9808591at2; -.
DR Proteomes; UP000095743; Chromosome.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR CDD; cd01335; Radical_SAM; 1.
DR CDD; cd21124; SPASM_CteB-like; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR023885; 4Fe4S-binding_SPASM_dom.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR000385; MoaA_NifB_PqqE_Fe-S-bd_CS.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR024025; SCIFF_rSAM_maturase.
DR InterPro; IPR047602; SPASM_CteB-like.
DR InterPro; IPR023867; Sulphatase_maturase_rSAM.
DR NCBIfam; TIGR04085; rSAM_more_4Fe4S; 1.
DR NCBIfam; TIGR03974; rSAM_six_Cys; 1.
DR PANTHER; PTHR43273; ANAEROBIC SULFATASE-MATURATING ENZYME HOMOLOG ASLB-RELATED; 1.
DR PANTHER; PTHR43273:SF8; RADICAL SAM PROTEIN-RELATED; 1.
DR Pfam; PF13353; Fer4_12; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR Pfam; PF13186; SPASM; 1.
DR SFLD; SFLDG01216; thioether_bond_formation_requi; 1.
DR SFLD; SFLDG01384; thioether_bond_formation_requi; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS01305; MOAA_NIFB_PQQE; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000095743};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 88..321
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 453 AA; 52521 MW; 195B464A0E474E5D CRC64;
MIHKFEMDGT RILIDVNSGA VHIIDEIVYN LLDFYQKEDK DTLLQIFKNQ YEQQEIIDAL
DEIKALETAG LLFTQDSYEA HPSFQNRRPV VKALCLHIAH DCNISCKYCF ASQGDFKGTR
SLMNETVGMK AIDFLIEHSG NRRNLEIDFF GGEPLMNLEV VKRIVDYGRS KEQSANKRFR
FTLTTNGILL NEENMAYINE HMENVVLSID GRKEVNDNMR KTLKGDGTYD IILPKLQKMA
EMRKNKNYYV RGTFTREHLD FAKDVLHLAE LGFQNTSVEP VVTEADKPYA IRHEDLPEIF
RQYEILAKEY VERKKNNRGF NFFHFMIDLN QGPCVIKRVS GCGAGSEYLA ITPEGDIYPC
HQFVGNEHFK MGNILDEQFN REVQTEFGNA HIYNKPQCRE CWAKFYCSGG CHANAYNFYQ
DVNRPYEIGC EMEKKRIECA LMIQAKLLSE EDN
//
