ID A0A1D8P4T8_9FLAO Unreviewed; 494 AA.
AC A0A1D8P4T8;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE RecName: Full=Probable malate:quinone oxidoreductase {ECO:0000256|HAMAP-Rule:MF_00212};
DE EC=1.1.5.4 {ECO:0000256|HAMAP-Rule:MF_00212};
DE AltName: Full=MQO {ECO:0000256|HAMAP-Rule:MF_00212};
DE AltName: Full=Malate dehydrogenase [quinone] {ECO:0000256|HAMAP-Rule:MF_00212};
GN Name=mqo {ECO:0000256|HAMAP-Rule:MF_00212};
GN ORFNames=LPB138_02335 {ECO:0000313|EMBL:AOW19585.1};
OS Urechidicola croceus.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Urechidicola.
OX NCBI_TaxID=1850246 {ECO:0000313|EMBL:AOW19585.1, ECO:0000313|Proteomes:UP000176050};
RN [1] {ECO:0000313|EMBL:AOW19585.1, ECO:0000313|Proteomes:UP000176050}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LPB0138 {ECO:0000313|EMBL:AOW19585.1,
RC ECO:0000313|Proteomes:UP000176050};
RA Kim E., Yi H.;
RT "Lutibacter sp. LPB0138, isolated from marine gastropod.";
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=(S)-malate + a quinone = a quinol + oxaloacetate;
CC Xref=Rhea:RHEA:46012, ChEBI:CHEBI:15589, ChEBI:CHEBI:16452,
CC ChEBI:CHEBI:24646, ChEBI:CHEBI:132124; EC=1.1.5.4;
CC Evidence={ECO:0000256|ARBA:ARBA00001139, ECO:0000256|HAMAP-
CC Rule:MF_00212};
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974,
CC ECO:0000256|HAMAP-Rule:MF_00212};
CC -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle;
CC oxaloacetate from (S)-malate (quinone route): step 1/1.
CC {ECO:0000256|ARBA:ARBA00005012, ECO:0000256|HAMAP-Rule:MF_00212}.
CC -!- SIMILARITY: Belongs to the MQO family. {ECO:0000256|HAMAP-
CC Rule:MF_00212}.
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DR EMBL; CP017478; AOW19585.1; -; Genomic_DNA.
DR RefSeq; WP_070235701.1; NZ_CP017478.1.
DR AlphaFoldDB; A0A1D8P4T8; -.
DR STRING; 1850246.LPB138_02335; -.
DR KEGG; lul:LPB138_02335; -.
DR OrthoDB; 9763983at2; -.
DR UniPathway; UPA00223; UER01008.
DR Proteomes; UP000176050; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0052589; F:malate dehydrogenase (menaquinone) activity; IEA:UniProtKB-EC.
DR GO; GO:0008924; F:malate dehydrogenase (quinone) activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00212; MQO; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR006231; MQO.
DR NCBIfam; TIGR01320; mal_quin_oxido; 1.
DR PANTHER; PTHR43104; L-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43104:SF2; L-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR Pfam; PF06039; Mqo; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827, ECO:0000256|HAMAP-Rule:MF_00212};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630, ECO:0000256|HAMAP-
KW Rule:MF_00212}; Membrane {ECO:0000256|SAM:Phobius};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002, ECO:0000256|HAMAP-
KW Rule:MF_00212}; Reference proteome {ECO:0000313|Proteomes:UP000176050};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Tricarboxylic acid cycle {ECO:0000256|HAMAP-Rule:MF_00212}.
FT TRANSMEM 7..24
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 494 AA; 55252 MW; 10D39CFA2650A19C CRC64;
MQNKPNNITL VGAGIMSATL GVLLKKLMPN CKIDIYERLD KVGAESSDAW NNAGTGHAAY
CELNYTPELE DGTIDISKAL KIGSSFEVSK QFWAYLKAEN HLPQSEAFIN DIAHMSFVWG
EENIEFLKKR FEALTNCVLF EEMKYSEDLE EIEKWIPLMM HNRIDDEKIA VTRMEIGTDV
NFGAITRGMI NYLQSCDGVE VHLGYNIDDL TKNKDGTWEI EMTDLATNKE KVVISDFVFI
GAGGGSIPLL EKTDLEQGRG YAGFPVSGQW LKCTNPEVIQ QHEAKVYGKA STGSPPMSVP
HLDTRMMNGK KALLFGPYAG FSTKFLKNGS YFDLPLSLEV HNIWPLLSAG IHNIDLTKYL
IKQVVQSDEE RFAFLQKYFP DAKMEDWTLE HAGQRVQIIK KDEDEGGVLK FGTEIVTDDD
GSLAALLGAS PGASTSVSIM LDVLDKCFPE AIASKEWQET LTTMIPSYGK SLVEHPELCR
TIRERTTREL KLDD
//
