ID A0A1D8PI20_CANAL Unreviewed; 562 AA.
AC A0A1D8PI20;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 28-JUN-2023, entry version 28.
DE SubName: Full=Ribosome biosynthesis protein {ECO:0000313|EMBL:AOW27732.1};
GN Name=NOC4 {ECO:0000313|CGD:CAL0000199787,
GN ECO:0000313|EMBL:AOW27732.1};
GN OrderedLocusNames=CAALFM_C207340WA {ECO:0000313|EMBL:AOW27732.1},
GN orf19.9458 {ECO:0000313|CGD:CAL0000199787};
OS Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=237561 {ECO:0000313|EMBL:AOW27732.1, ECO:0000313|Proteomes:UP000000559};
RN [1] {ECO:0000313|EMBL:AOW27732.1, ECO:0000313|Proteomes:UP000000559}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SC5314 / ATCC MYA-2876 {ECO:0000313|Proteomes:UP000000559};
RX PubMed=15123810; DOI=10.1073/pnas.0401648101;
RA Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B.,
RA Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W.,
RA Scherer S.;
RT "The diploid genome sequence of Candida albicans.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004).
RN [2] {ECO:0000313|EMBL:AOW27732.1, ECO:0000313|Proteomes:UP000000559}
RP GENOME REANNOTATION.
RC STRAIN=SC5314 / ATCC MYA-2876 {ECO:0000313|Proteomes:UP000000559};
RX PubMed=17419877; DOI=.1186/gb-2007-8-4-r52;
RA van het Hoog M., Rast T.J., Martchenko M., Grindle S., Dignard D.,
RA Hogues H., Cuomo C., Berriman M., Scherer S., Magee B.B., Whiteway M.,
RA Chibana H., Nantel A., Magee P.T.;
RT "Assembly of the Candida albicans genome into sixteen supercontigs aligned
RT on the eight chromosomes.";
RL Genome Biol. 8:RESEARCH52.1-RESEARCH52.12(2007).
RN [3] {ECO:0000313|EMBL:AOW27732.1, ECO:0000313|Proteomes:UP000000559}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SC5314 / ATCC MYA-2876 {ECO:0000313|Proteomes:UP000000559};
RX PubMed=24025428; DOI=.1186/gb-2013-14-9-r97;
RA Muzzey D., Schwartz K., Weissman J.S., Sherlock G.;
RT "Assembly of a phased diploid Candida albicans genome facilitates allele-
RT specific measurements and provides a simple model for repeat and indel
RT structure.";
RL Genome Biol. 14:RESEARCH97.1-RESEARCH97.14(2013).
CC -!- SIMILARITY: Belongs to the CBF/MAK21 family.
CC {ECO:0000256|ARBA:ARBA00007797}.
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DR EMBL; CP017624; AOW27732.1; -; Genomic_DNA.
DR RefSeq; XP_713159.2; XM_708066.2.
DR AlphaFoldDB; A0A1D8PI20; -.
DR SMR; A0A1D8PI20; -.
DR STRING; 237561.A0A1D8PI20; -.
DR EnsemblFungi; C2_07340W_A-T; C2_07340W_A-T-p1; C2_07340W_A.
DR GeneID; 3645224; -.
DR KEGG; cal:CAALFM_C207340WA; -.
DR CGD; CAL0000199787; NOC4.
DR VEuPathDB; FungiDB:C2_07340W_A; -.
DR eggNOG; KOG2154; Eukaryota.
DR InParanoid; A0A1D8PI20; -.
DR OMA; KHPTCMI; -.
DR OrthoDB; 7420at2759; -.
DR Proteomes; UP000000559; Chromosome 2.
DR GO; GO:0005829; C:cytosol; IEA:EnsemblFungi.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0030692; C:Noc4p-Nop14p complex; IBA:GO_Central.
DR GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR GO; GO:0032040; C:small-subunit processome; IBA:GO_Central.
DR GO; GO:0000480; P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:EnsemblFungi.
DR GO; GO:0000447; P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:EnsemblFungi.
DR GO; GO:0000472; P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:EnsemblFungi.
DR InterPro; IPR005612; CCAAT-binding_factor.
DR InterPro; IPR027193; Noc4.
DR PANTHER; PTHR12455; NUCLEOLAR COMPLEX PROTEIN 4; 1.
DR PANTHER; PTHR12455:SF0; NUCLEOLAR COMPLEX PROTEIN 4 HOMOLOG; 1.
DR Pfam; PF03914; CBF; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000559};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 416..436
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 347..494
FT /note="CCAAT-binding factor"
FT /evidence="ECO:0000259|Pfam:PF03914"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 562 AA; 65231 MW; 18ED1CC8DD716E3A CRC64;
MAPKRKSVKG GVEPKNKKVK TAIHQKEPNT LLSLEELTNL SKEIDESLKF NNLVPLLEQF
KLIKTKLIES IDPDVESTAR KLSLLLYRNF NKINDEIISN GNGAKSSASE DKKMIIKWLS
EKYTTFKDII YGFIEDKLAG STSLQLDLLD IILNFIRLES QRKSSTSQVV FFPTQSYKSL
TESILNSKNG EISFDGTTDN FIVLEFLDKF QKYWDLQFYF FNNLSEVLNE WKQEKSEKDL
QLIFANFLTV LRKGLLFNEK TLEEEPLWIA PNKEGKLPSS LYKHTLFKSQ FQKSVIAMLS
YPLLQEQYKS VLMILHKRII PYMSQPQSLM DFLTDCYDLT DDLIVPILAL NSLYELMKNY
NLEYPDFYSK LYSLLTPELL YTKYRSRFFR LCDLFLSSTH LSANLVASFI KKLARISLAA
SASGVVIIIP FIYNLLKRHP TCMIMLHKED TESGYQDPFN SEEKNPLHTE AIKSSLWELD
TLMTHYHPNV ATLAKIFGEP FRKPSYNMED FLDWSYNSLL QSEYDRKFKD KNSALEFEEF
DKVLDTSNSD SKSSLLEGWT LV
//
