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Database: UniProt
Entry: A0A1D8PJH8_CANAL
LinkDB: A0A1D8PJH8_CANAL
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ID   A0A1D8PJH8_CANAL        Unreviewed;       309 AA.
AC   A0A1D8PJH8;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   10-APR-2019, entry version 13.
DE   SubName: Full=Prephenate dehydratase {ECO:0000313|EMBL:AOW28281.1};
GN   Name=PHA2 {ECO:0000313|CGD:CAL0000185001,
GN   ECO:0000313|EMBL:AOW28281.1};
GN   OrderedLocusNames=orf19.234 {ECO:0000313|CGD:CAL0000185001};
GN   ORFNames=CAALFM_C302460CA {ECO:0000313|EMBL:AOW28281.1};
OS   Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
OC   Saccharomycetes; Saccharomycetales; Debaryomycetaceae;
OC   Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=237561 {ECO:0000313|EMBL:AOW28281.1, ECO:0000313|Proteomes:UP000000559};
RN   [1] {ECO:0000313|EMBL:AOW28281.1, ECO:0000313|Proteomes:UP000000559}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SC5314 / ATCC MYA-2876 {ECO:0000313|Proteomes:UP000000559};
RX   PubMed=15123810; DOI=10.1073/pnas.0401648101;
RA   Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S.,
RA   Magee B.B., Newport G., Thorstenson Y.R., Agabian N., Magee P.T.,
RA   Davis R.W., Scherer S.;
RT   "The diploid genome sequence of Candida albicans.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004).
RN   [2] {ECO:0000313|EMBL:AOW28281.1, ECO:0000313|Proteomes:UP000000559}
RP   GENOME REANNOTATION.
RC   STRAIN=SC5314 / ATCC MYA-2876 {ECO:0000313|Proteomes:UP000000559};
RX   PubMed=17419877; DOI=10.1186/gb-2007-8-4-r52;
RA   van het Hoog M., Rast T.J., Martchenko M., Grindle S., Dignard D.,
RA   Hogues H., Cuomo C., Berriman M., Scherer S., Magee B.B., Whiteway M.,
RA   Chibana H., Nantel A., Magee P.T.;
RT   "Assembly of the Candida albicans genome into sixteen supercontigs
RT   aligned on the eight chromosomes.";
RL   Genome Biol. 8:RESEARCH52.1-RESEARCH52.12(2007).
RN   [3] {ECO:0000313|EMBL:AOW28281.1, ECO:0000313|Proteomes:UP000000559}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SC5314 / ATCC MYA-2876 {ECO:0000313|Proteomes:UP000000559};
RX   PubMed=24025428; DOI=10.1186/gb-2013-14-9-r97;
RA   Muzzey D., Schwartz K., Weissman J.S., Sherlock G.;
RT   "Assembly of a phased diploid Candida albicans genome facilitates
RT   allele-specific measurements and provides a simple model for repeat
RT   and indel structure.";
RL   Genome Biol. 14:RESEARCH97.1-RESEARCH97.14(2013).
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DR   EMBL; CP017625; AOW28281.1; -; Genomic_DNA.
DR   RefSeq; XP_019330844.1; XM_019475299.1.
DR   STRING; 5476.C4YQ16; -.
DR   GeneID; 3638346; -.
DR   KEGG; cal:CAALFM_C302460CA; -.
DR   CGD; CAL0000185001; PHA2.
DR   EuPathDB; FungiDB:C3_02460C_A; -.
DR   KO; K04518; -.
DR   OrthoDB; 1090069at2759; -.
DR   Proteomes; UP000000559; Chromosome 3.
DR   GO; GO:0004106; F:chorismate mutase activity; IEA:InterPro.
DR   GO; GO:0004664; F:prephenate dehydratase activity; IBA:GO_Central.
DR   GO; GO:0009094; P:L-phenylalanine biosynthetic process; IBA:GO_Central.
DR   InterPro; IPR002912; ACT_dom.
DR   InterPro; IPR008242; Chor_mutase/pphenate_deHydtase.
DR   InterPro; IPR001086; Preph_deHydtase.
DR   InterPro; IPR018528; Preph_deHydtase_CS.
DR   Pfam; PF01842; ACT; 1.
DR   Pfam; PF00800; PDT; 1.
DR   PIRSF; PIRSF001500; Chor_mut_pdt_Ppr; 1.
DR   PROSITE; PS51671; ACT; 1.
DR   PROSITE; PS00857; PREPHENATE_DEHYDR_1; 1.
DR   PROSITE; PS51171; PREPHENATE_DEHYDR_3; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000000559};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000559}.
FT   DOMAIN        4    194       Prephenate dehydratase.
FT                                {ECO:0000259|PROSITE:PS51171}.
FT   DOMAIN      223    300       ACT. {ECO:0000259|PROSITE:PS51671}.
SQ   SEQUENCE   309 AA;  34763 MW;  64D616BAC41D71F3 CRC64;
     MTIKVAFLGP EGTYTHQALI QQFGTENVSI YPQQSIGDCF HILNEKKVDY AVVPFENSTN
     GQVVFTYDLL RDWYFQTSTP PKFRIIAEQF VSIHHNLLTN ASKIEDIKTI YSHPQVWTQV
     NKFLQSLPQQ ITKIDVGSTS KAAEIVSQDT ITTSGSSSAA ISSYMSSELY KLPILKEGIE
     DNQSNTTRFL ILGYDSPISP PPAAASNNDD DNSKRNTTIV SSIMFTLNHD DPGALCDVLV
     KFKEYGITLT SINSRPANLK PWQYVFFVEM IGDIHQEGLV EKIKESCLEL VILGVFQRSW
     RYNNNSNDQ
//
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