ID A0A1D8PSP4_CANAL Unreviewed; 923 AA.
AC A0A1D8PSP4;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE SubName: Full=Mismatch repair ATPase {ECO:0000313|EMBL:AOW31150.1};
GN OrderedLocusNames=CAALFM_CR04120CA {ECO:0000313|EMBL:AOW31150.1},
GN orf19.8126 {ECO:0000313|CGD:CAL0000200606};
OS Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=237561 {ECO:0000313|EMBL:AOW31150.1, ECO:0000313|Proteomes:UP000000559};
RN [1] {ECO:0000313|EMBL:AOW31150.1, ECO:0000313|Proteomes:UP000000559}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SC5314 / ATCC MYA-2876 {ECO:0000313|Proteomes:UP000000559};
RX PubMed=15123810; DOI=10.1073/pnas.0401648101;
RA Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B.,
RA Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W.,
RA Scherer S.;
RT "The diploid genome sequence of Candida albicans.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004).
RN [2] {ECO:0000313|EMBL:AOW31150.1, ECO:0000313|Proteomes:UP000000559}
RP GENOME REANNOTATION.
RC STRAIN=SC5314 / ATCC MYA-2876 {ECO:0000313|Proteomes:UP000000559};
RX PubMed=17419877; DOI=.1186/gb-2007-8-4-r52;
RA van het Hoog M., Rast T.J., Martchenko M., Grindle S., Dignard D.,
RA Hogues H., Cuomo C., Berriman M., Scherer S., Magee B.B., Whiteway M.,
RA Chibana H., Nantel A., Magee P.T.;
RT "Assembly of the Candida albicans genome into sixteen supercontigs aligned
RT on the eight chromosomes.";
RL Genome Biol. 8:RESEARCH52.1-RESEARCH52.12(2007).
RN [3] {ECO:0000313|EMBL:AOW31150.1, ECO:0000313|Proteomes:UP000000559}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SC5314 / ATCC MYA-2876 {ECO:0000313|Proteomes:UP000000559};
RX PubMed=24025428; DOI=.1186/gb-2013-14-9-r97;
RA Muzzey D., Schwartz K., Weissman J.S., Sherlock G.;
RT "Assembly of a phased diploid Candida albicans genome facilitates allele-
RT specific measurements and provides a simple model for repeat and indel
RT structure.";
RL Genome Biol. 14:RESEARCH97.1-RESEARCH97.14(2013).
CC -!- SIMILARITY: Belongs to the DNA mismatch repair MutS family.
CC {ECO:0000256|ARBA:ARBA00006271}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP017630; AOW31150.1; -; Genomic_DNA.
DR RefSeq; XP_717359.2; XM_712266.2.
DR AlphaFoldDB; A0A1D8PSP4; -.
DR SMR; A0A1D8PSP4; -.
DR STRING; 237561.A0A1D8PSP4; -.
DR EnsemblFungi; CR_04120C_A-T; CR_04120C_A-T-p1; CR_04120C_A.
DR GeneID; 3640972; -.
DR KEGG; cal:CAALFM_CR04120CA; -.
DR CGD; CAL0000200606; orf19.8126.
DR VEuPathDB; FungiDB:CR_04120C_A; -.
DR eggNOG; ENOG502QUUG; Eukaryota.
DR InParanoid; A0A1D8PSP4; -.
DR OrthoDB; 168255at2759; -.
DR Proteomes; UP000000559; Chromosome R.
DR GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0032139; F:dinucleotide insertion or deletion binding; IEA:EnsemblFungi.
DR GO; GO:0003690; F:double-stranded DNA binding; IBA:GO_Central.
DR GO; GO:0032137; F:guanine/thymine mispair binding; IEA:EnsemblFungi.
DR GO; GO:0006298; P:mismatch repair; IEA:EnsemblFungi.
DR GO; GO:0043504; P:mitochondrial DNA repair; IBA:GO_Central.
DR Gene3D; 1.10.1420.10; -; 1.
DR Gene3D; 3.40.1170.10; DNA repair protein MutS, domain I; 1.
DR Gene3D; 3.30.420.110; MutS, connector domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR007695; DNA_mismatch_repair_MutS-lik_N.
DR InterPro; IPR017261; DNA_mismatch_repair_MutS/MSH.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR InterPro; IPR016151; DNA_mismatch_repair_MutS_N.
DR InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR InterPro; IPR007860; DNA_mmatch_repair_MutS_con_dom.
DR InterPro; IPR036678; MutS_con_dom_sf.
DR InterPro; IPR045076; MutS_family.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11361:SF34; DNA MISMATCH REPAIR PROTEIN MSH1, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR Pfam; PF01624; MutS_I; 1.
DR Pfam; PF05188; MutS_II; 1.
DR Pfam; PF05192; MutS_III; 1.
DR Pfam; PF00488; MutS_V; 1.
DR PIRSF; PIRSF037677; DNA_mis_repair_Msh6; 1.
DR SMART; SM00534; MUTSac; 1.
DR SMART; SM00533; MUTSd; 1.
DR SUPFAM; SSF55271; DNA repair protein MutS, domain I; 1.
DR SUPFAM; SSF53150; DNA repair protein MutS, domain II; 1.
DR SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000000559}.
FT DOMAIN 807..823
FT /note="DNA mismatch repair proteins mutS family"
FT /evidence="ECO:0000259|PROSITE:PS00486"
SQ SEQUENCE 923 AA; 104360 MW; A22D65FAD48EB735 CRC64;
MILRRNNIIP LRHLTSGCRL FARKAATKKA PSPLLEEWDR GGRNQDTGLS PLLASMKRLI
DSNPGCVSLI QVGSFYELYF EQAEEYGPKL GLKIAKKKTS NHVVPFAGFP TTQLRKFTEM
LIHEQQVNVA IIDQCDQGSK TNQNLVHRKI SRIITPGTLI DESFLNFNEN NYLVAISFAP
SSLSLPPDPQ MKVGLSWTDI SVGESFVQLT TLGELSSDIA RINPSEILLP KEFQDHNLHL
GQWYSPLQEL KRYIIRYHST TNYNELKLQY HDSIQKVRRH LETFSPREQA ALNMIMSYMS
INLPDVDILM TLPTRYFNET CLQMDSRTRE ALELTERTIA GRTSSVGSLV SVIKRTCTSS
GTRLLTEWIK SPSLDTKDIE KRQSFVKMFL KNQHLKIVTR QHLQQLGDFI RNLQKLVVGR
GDPVNQLVYA ASTLDGLQKL RDFLVEEYEQ NPKKLSCLKN LLEKFDIPKH LAEKIYNTID
IEEQTIPGEG SEEIEEPTEV VEDTNSSYTN SFLEKYRSKQ EGNTDAENFY SVKRDFNDEL
KILHDELSEL EVEEHKLWSK LRNVLDDIDV KLNIGKKIVL GRYNNVILIT GKTSSISKAS
AKLDGDILYE KKMSLVYRST EWNDIQHLIL DKKEAILLVE RKIIEELKSE VTRRFPEFRE
LAGLADFLDV TSSLAIVAEE NNWTCPKLIK TPRLSVEGGR HVVVESSLKD SGNMFIPNDS
KMGTDGTLWV ISGPNMGGKS TYLRQNALIV ILAQIGSFVP AEKATIGLVD KIFTRIGATD
DLFNDLSTFM VEMVEVSNIL TNATPSSLAI VDEIGRGTSG KEGLAIAYAT LLSLLQVNKC
RTLFATHFGK ELEQLLVANN IDQKNIRYFR TRVLENGDNE KGFVIDHTLE PGISERSHAL
DVARMAGFPE NALKAAEKVL DNL
//
