ID A0A1D8PSR6_CANAL Unreviewed; 373 AA.
AC A0A1D8PSR6;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=Fe2OG dioxygenase domain-containing protein {ECO:0000259|PROSITE:PS51471};
GN OrderedLocusNames=CAALFM_CR04500CA {ECO:0000313|EMBL:AOW31186.1},
GN orf19.8174 {ECO:0000313|CGD:CAL0000187380};
OS Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=237561 {ECO:0000313|EMBL:AOW31186.1, ECO:0000313|Proteomes:UP000000559};
RN [1] {ECO:0000313|EMBL:AOW31186.1, ECO:0000313|Proteomes:UP000000559}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SC5314 / ATCC MYA-2876 {ECO:0000313|Proteomes:UP000000559};
RX PubMed=15123810; DOI=10.1073/pnas.0401648101;
RA Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B.,
RA Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W.,
RA Scherer S.;
RT "The diploid genome sequence of Candida albicans.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004).
RN [2] {ECO:0000313|EMBL:AOW31186.1, ECO:0000313|Proteomes:UP000000559}
RP GENOME REANNOTATION.
RC STRAIN=SC5314 / ATCC MYA-2876 {ECO:0000313|Proteomes:UP000000559};
RX PubMed=17419877; DOI=.1186/gb-2007-8-4-r52;
RA van het Hoog M., Rast T.J., Martchenko M., Grindle S., Dignard D.,
RA Hogues H., Cuomo C., Berriman M., Scherer S., Magee B.B., Whiteway M.,
RA Chibana H., Nantel A., Magee P.T.;
RT "Assembly of the Candida albicans genome into sixteen supercontigs aligned
RT on the eight chromosomes.";
RL Genome Biol. 8:RESEARCH52.1-RESEARCH52.12(2007).
RN [3] {ECO:0000313|EMBL:AOW31186.1, ECO:0000313|Proteomes:UP000000559}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SC5314 / ATCC MYA-2876 {ECO:0000313|Proteomes:UP000000559};
RX PubMed=24025428; DOI=.1186/gb-2013-14-9-r97;
RA Muzzey D., Schwartz K., Weissman J.S., Sherlock G.;
RT "Assembly of a phased diploid Candida albicans genome facilitates allele-
RT specific measurements and provides a simple model for repeat and indel
RT structure.";
RL Genome Biol. 14:RESEARCH97.1-RESEARCH97.14(2013).
CC -!- SIMILARITY: Belongs to the iron/ascorbate-dependent oxidoreductase
CC family. {ECO:0000256|RuleBase:RU003682}.
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DR EMBL; CP017630; AOW31186.1; -; Genomic_DNA.
DR RefSeq; XP_717404.2; XM_712311.2.
DR AlphaFoldDB; A0A1D8PSR6; -.
DR SMR; A0A1D8PSR6; -.
DR STRING; 237561.A0A1D8PSR6; -.
DR EnsemblFungi; CR_04500C_A-T; CR_04500C_A-T-p1; CR_04500C_A.
DR GeneID; 3641014; -.
DR KEGG; cal:CAALFM_CR04500CA; -.
DR CGD; CAL0000187380; orf19.8174.
DR VEuPathDB; FungiDB:CR_04500C_A; -.
DR eggNOG; KOG0143; Eukaryota.
DR InParanoid; A0A1D8PSR6; -.
DR OMA; MSLELCA; -.
DR OrthoDB; 1380829at2759; -.
DR Proteomes; UP000000559; Chromosome R.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:1901362; P:organic cyclic compound biosynthetic process; IEA:UniProt.
DR GO; GO:0044283; P:small molecule biosynthetic process; IEA:UniProt.
DR InterPro; IPR026992; DIOX_N.
DR InterPro; IPR044861; IPNS-like_FE2OG_OXY.
DR InterPro; IPR027443; IPNS-like_sf.
DR InterPro; IPR005123; Oxoglu/Fe-dep_dioxygenase.
DR PANTHER; PTHR47990; 2-OXOGLUTARATE (2OG) AND FE(II)-DEPENDENT OXYGENASE SUPERFAMILY PROTEIN-RELATED; 1.
DR PANTHER; PTHR47990:SF62; IRON_ASCORBATE OXIDOREDUCTASE DDB_G0283291-RELATED; 1.
DR Pfam; PF03171; 2OG-FeII_Oxy; 1.
DR Pfam; PF14226; DIOX_N; 1.
DR SUPFAM; SSF51197; Clavaminate synthase-like; 1.
DR PROSITE; PS51471; FE2OG_OXY; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|RuleBase:RU003682};
KW Metal-binding {ECO:0000256|RuleBase:RU003682};
KW Oxidoreductase {ECO:0000256|RuleBase:RU003682};
KW Reference proteome {ECO:0000313|Proteomes:UP000000559}.
FT DOMAIN 175..293
FT /note="Fe2OG dioxygenase"
FT /evidence="ECO:0000259|PROSITE:PS51471"
SQ SEQUENCE 373 AA; 42229 MW; 9B7D2DE2D065DAAC CRC64;
MSFQEIPIID LQEAFDPATR SKFLEEVRDA IINVGFLLLK NYESLGPTEE DLQSIKQQAI
EFFALPAKEK LQCEMLNSPH FLGYTRLANE ITASHTDWRE QIDLATELPA PKEGEPLYKN
IEGPNLWPNP EVIPKFRPTI ERFIEKMTAL SNVFKDLVAE SIGVDPKALN RYFKENQQCK
MKLIAYPDVS ELDGTKSAAL DDTPETNQGV GPHRDSDLIT YIYQATEHQN SLQVQNFQGH
WITVPNIPGH LVVNNGQTLQ AITGGVAKAT IHRVLVPEKG TGTRISIPFF QTIDLDSSKG
VVDNLPQEVI DLKNERDKKI KDWGVDTGFQ FEPDVSKEPI GHAVFRNRIK SHQDVAKKWY
PDVLKSVLQE YTH
//
