ID A0A1D8PSZ1_CANAL Unreviewed; 1278 AA.
AC A0A1D8PSZ1;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=Protein bir1 {ECO:0008006|Google:ProtNLM};
GN Name=BIR1 {ECO:0000313|CGD:CAL0000178244};
GN OrderedLocusNames=CAALFM_CR05100WA {ECO:0000313|EMBL:AOW31239.1},
GN orf19.8257 {ECO:0000313|CGD:CAL0000178244};
OS Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=237561 {ECO:0000313|EMBL:AOW31239.1, ECO:0000313|Proteomes:UP000000559};
RN [1] {ECO:0000313|EMBL:AOW31239.1, ECO:0000313|Proteomes:UP000000559}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SC5314 / ATCC MYA-2876 {ECO:0000313|Proteomes:UP000000559};
RX PubMed=15123810; DOI=10.1073/pnas.0401648101;
RA Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B.,
RA Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W.,
RA Scherer S.;
RT "The diploid genome sequence of Candida albicans.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004).
RN [2] {ECO:0000313|EMBL:AOW31239.1, ECO:0000313|Proteomes:UP000000559}
RP GENOME REANNOTATION.
RC STRAIN=SC5314 / ATCC MYA-2876 {ECO:0000313|Proteomes:UP000000559};
RX PubMed=17419877; DOI=.1186/gb-2007-8-4-r52;
RA van het Hoog M., Rast T.J., Martchenko M., Grindle S., Dignard D.,
RA Hogues H., Cuomo C., Berriman M., Scherer S., Magee B.B., Whiteway M.,
RA Chibana H., Nantel A., Magee P.T.;
RT "Assembly of the Candida albicans genome into sixteen supercontigs aligned
RT on the eight chromosomes.";
RL Genome Biol. 8:RESEARCH52.1-RESEARCH52.12(2007).
RN [3] {ECO:0000313|EMBL:AOW31239.1, ECO:0000313|Proteomes:UP000000559}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SC5314 / ATCC MYA-2876 {ECO:0000313|Proteomes:UP000000559};
RX PubMed=24025428; DOI=.1186/gb-2013-14-9-r97;
RA Muzzey D., Schwartz K., Weissman J.S., Sherlock G.;
RT "Assembly of a phased diploid Candida albicans genome facilitates allele-
RT specific measurements and provides a simple model for repeat and indel
RT structure.";
RL Genome Biol. 14:RESEARCH97.1-RESEARCH97.14(2013).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP017630; AOW31239.1; -; Genomic_DNA.
DR RefSeq; XP_711989.2; XM_706896.2.
DR AlphaFoldDB; A0A1D8PSZ1; -.
DR STRING; 237561.A0A1D8PSZ1; -.
DR EnsemblFungi; CR_05100W_A-T; CR_05100W_A-T-p1; CR_05100W_A.
DR GeneID; 3646403; -.
DR KEGG; cal:CAALFM_CR05100WA; -.
DR CGD; CAL0000178244; BIR1.
DR VEuPathDB; FungiDB:CR_05100W_A; -.
DR eggNOG; KOG1101; Eukaryota.
DR InParanoid; A0A1D8PSZ1; -.
DR OrthoDB; 2882335at2759; -.
DR Proteomes; UP000000559; Chromosome R.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0006915; P:apoptotic process; IMP:CGD.
DR GO; GO:0051726; P:regulation of cell cycle; IBA:GO_Central.
DR GO; GO:0043067; P:regulation of programmed cell death; IEA:UniProt.
DR CDD; cd00022; BIR; 1.
DR InterPro; IPR001370; BIR_rpt.
DR PANTHER; PTHR10044:SF139; DEATH-ASSOCIATED INHIBITOR OF APOPTOSIS 2; 1.
DR PANTHER; PTHR10044; INHIBITOR OF APOPTOSIS; 1.
DR Pfam; PF00653; BIR; 2.
DR SMART; SM00238; BIR; 2.
DR SUPFAM; SSF57924; Inhibitor of apoptosis (IAP) repeat; 2.
DR PROSITE; PS50143; BIR_REPEAT_2; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000000559}.
FT REGION 448..672
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 685..735
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 776..802
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 858..885
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 899..933
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 952..1091
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1142..1176
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 449..474
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 497..517
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 526..544
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 559..576
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 586..602
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 603..620
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 627..657
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 685..699
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 707..735
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 787..802
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 863..882
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 906..933
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 952..994
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 995..1017
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1018..1085
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1142..1156
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1278 AA; 146077 MW; 1FA0112BA0C0F4E6 CRC64;
MANINHEMIY RDHRLKTFED PIKIGNKSLA WDEFSDVENF DRLIDSGFYY NPTPRSKTRI
TCAYCGNSEI IKSNKDVENI NTKHLRRNSS CPMSLIANID DIITSFNQNR DELKNFWTDH
EKFNDPFQSK TIEFRKQFYV NYPLDKIDSI PNSNSLSHAG FIYSPRSIED DRVRCMYCQC
ALDYWEEDDD PIQEHIRNES TYCYFLDLYN NEQDGDKDSL ELENPITKSI NDIDHEEGNI
DNKIDNNNDY NNNDNDDDEE IIELASFHAS ENDNDNKTKD DVISISDDST TSLPQEITNK
HKHDTSVNKM NDSFSTPVKD ISQDLSIIEQ DERPTYRRSK RIKRLYGEKD RNVDYWDKLP
DEDLLQEFIE VSQKSSQHNN SKRKSSIINK NLIENSLLYN ESTDDNGIDD IGDIKIHNDS
DIEEVIDNDE IPMDEIEIEM EDVYVEENKS NDLSQQKQQA KDTTANGKGE YQLQSDNVSD
KDKSTEPRSQ KQLSFANGDD NEDKDLDIEK GEQAKVDLSK DINGFSPVIQ EDSDSNSDSN
SNSDGTDNKN REDVNSNSEK EEFDLEDSDD ESEYHSDENS ESYADSSDES FKISGNFDDT
TQELENPKTK QRKSTSKTPA KETETSKQNN SKAKVKGKDI SKSEPKKPKR VVISKKEKST
TPLENLFDNT DDNLEYDEKH IEKIENEPST HLLEPKKLKK KNTISKKTKS KTSEQKQIET
KQLEPTKRKF EEPNTSPIRF LDSLKNLQRK RKKLFKPNIL DMSFETAEVL SSPNKFLSSK
NETGVNVKDD SSPEKTHKQN NVTIEEKVVD EKVKIDKEDT PTGTKINSLS KTKNLKNSNT
VIDLNDNDMV VDPDEELVPG ITKSSGLPNS NVPTTDANNS TKEESSILKD LDSFVSFEKS
PKPKIAEIQA TSTSNNSRIS FVVESESSDN DSYSNYIQDI KQIDDEISKV MLEDSESHSL
TKVDTNEKEE SIMNDSNYED SEKKSIKEQD PDGMDIDASD LLVEEEEEAE EELIIDSTEE
LQSNQKASPI RNSSEMTAGN DRSLEEITGP NDSPPKVKNT DTYYSPDNTK ELPSKSLTKA
SESDITKNQE ITKEFKETKV ESSAITKKHS LEIDEKHYPD VLGIGGLATS PLGMNSSLTE
IHRLNNNNNS SNENDNDNGG VEEEEEEEKK KLQPSLKWQS RSMSQFIEQT KFLESSANEL
KDLACSEYDL HDDVTGDLTK FIAEMPEEEE EMTIKQWIEH CAANCKDIVT QSCTEINDFI
LEEYDRAIKM IEEMPTED
//
